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The Right to Reproductive Choice in Lombok, Indonesia - A minor field study on national implementation of international human rights law

This is a thesis on women's right to reproductive choice and the implementation of this right on the Indonesian island of Lombok. As this is a graduate thesis on the Master Program in Human Rights Law, the point of departure is the regulation of the right to reproductive choice in international human rights law. To establish the content and scope of the right to reproductive choice, the materi

Does Microcredit Reduce Poverty?

Despite efforts to end it, poverty still persists in the world today. Lately, microcredit has received much attention as a possible remedy. Even though there are many studies investigating the effects of microcredit there is a lack of research on the impact of microcredit on national poverty. Therefore the purpose of this study is to investigate that particular aspect by analyzing the impact so fa

Applying Knowledge Based Engineering at Volvo Parts

The focus of company’s aftermarket is no longer only the “machine shop” where aftermarket finds solutions to offer spare parts to the customers. Instead aftermarket is focused on technological improvements that continue to change and improve on the way aftermarket operates. The way aftermarket operates has shifted from reading documents to be more integrated with computers and the next step is, fo

Pharmaceutical Manufacturer Strategies to Parallel Importation in the EU: A Strategic Update in Light of European Court of Justice Rulings

Problem: Parallel trade occurs when a product is released on one market, and an importer purchases the product in question on a lower priced market, and subsequently imports the product to a higher priced market, and sells it there. Parallel trade of pharmaceuticals in the European Union is prevalent since the legal, business and political environment makes the trade relatively easy and legal. Thi

Neurocognitive outcomes in long-term survivors of Wilms tumor : a report from the St. Jude Lifetime Cohort

Purpose: To examine prevalence and predictors of neurocognitive outcomes, social attainment, emotional distress, and health-related quality of life (HRQOL) in long-term survivors of pediatric Wilms tumor (WT). Methods: One hundred fifty-eight WT survivors (59% female; mean [SD] age 33 [9.1] years; time since diagnosis 29 [9.1] years) and 354 community controls (55.6% female; 35 [10.2] years) compl

Nils Wohlin och frågan om arvssedvänjor

Nils Wohlin and the question of inheritance patternsIt has long been assumed that inheritance patterns varied strongly betweendifferent regions. In the early 20th century statistician Nils Wohlin made afamous account of Swedish inheritance patterns, claiming significant differences between Swedish provinces, especially between eastern and western Sweden. Newer studies of inheritance patterns have

Measuring next of kin’s experience of participation in the care of older people in nursing homes

Background Lack of conceptual clarity and measurement methods have led to underdeveloped efforts to measure experience of participation in care by next of kin to older people in nursing homes. Objective We sought to assess the measurement properties of items aimed at operationalizing participation in care by next of kin, applied in nursing homes. Methods A total of 37 items operationalizing partic

Low Adherence to Statin Treatment during the First Year after an Acute Myocardial Infarction is associated with Increased Second Year Mortality Risk- An Inverse Probability of Treatment Weighted Study on 54,872 Patients

AIMS: Experiencing an acute myocardial infarction (AMI) is a life-threatening event and use of statins can reduce the probability of recurrence and improve long term survival. However, the effectiveness of statins in the real-world setting may be lower than the reported efficacy in randomized clinical trials. Therefore, we aimed to investigate whether low statin treatment adherence during the year

The efficacy of the modified Atkins diet in North Sea Progressive Myoclonus Epilepsy : An observational prospective open-label study

Background: North Sea Progressive Myoclonus Epilepsy is a rare and severe disorder caused by mutations in the GOSR2 gene. It is clinically characterized by progressive myoclonus, seizures, early-onset ataxia and areflexia. As in other progressive myoclonus epilepsies, the efficacy of antiepileptic drugs is disappointingly limited in North Sea Progressive Myoclonus Epilepsy. The ketogenic diet and

Computer-assisted reading intervention for children with sensorineural hearing loss using hearing aids : Effects on auditory event-related potentials and mismatch negativity

Objectives: The primary aim was to investigate whether computer-assisted reading intervention somehow can affect event-related potentials (ERP) and mismatch negativity (MMN) in hearing impaired (HI) children with hearing aids (HAs) and normal hearing (NH) children. Methods: The study included 15 HI children with sensorineural hearing loss (SNHL) using bilateral HAs and 14 NH children as a referenc

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations

Immunophenotypic characterization and molecular analysis have long been used to delineate heterogeneity and define distinct cell populations. FACS is inherently a single-cell assay, however prior to molecular analysis, the target cells are often prospectively isolated in bulk, thereby losing single-cell resolution. Single-cell gene expression analysis provides a means to understand molecular diffe

S100A9 in inflammatory disease: a potential target for amelioration

The quinoline-3-carboxamides (Q compounds) are a family of small molecules with immunomodulatory functions that have shown efficacy in various murine models of inflammatory diseases. One such compound has demonstrated antitumor effects in murine models. Q compounds bind to S100A9, thereby preventing its ligation to TLR4 and RAGE. S100A9 is a small molecule which has shown to have a role in the est

A 200 ka glaciation history from NW Svalbard

Late Quaternary sedimentary units at Kongsfjordhallet, NW Svalbard, represent five cycles of glaciations and subsequent deglaciations during high relative sea levels. The high sea-level events are interpreted as glacioisostatically induced and imply preceding regional glaciations, which we constrain in time by luminescence and radiocarbon ages to just prior to ~195 ka, ~130 ka, ~85 ka, ~60 ka and

Spatiotemporal analysis of nonlinear trends in precipitation over Germany during 1951–2013 from multiple observation-based gridded products

Spatial and temporal patterns of trends in annual and seasonal precipitation over Germany during 1951–2013 were analysed using the ensemble empirical mode decomposition (EEMD) method. Three widely used and recognized high-resolution observation-based gridded precipitation products, the Climatic Research Unit (CRU) time-series data, Global Precipitation Climatology Centre (GPCC) Full Data Reanalysi

Associations between misfolded alpha-synuclein aggregates and Alzheimer's disease pathology in vivo

INTRODUCTION: We examined the relations of misfolded alpha synuclein (α-synuclein) with Alzheimer's disease (AD) biomarkers in two large independent cohorts. METHODS: We included Biomarkers for Identifying Neurodegenerative Disorders Early and Reliably Two (BioFINDER-2) and Alzheimer's Disease Neuroimaging Initiative (ADNI) participants (n = 2315, cognitively unimpaired, mild cognitive impairment,

Interventions for Young Women’s STEM Interest : Targeting the Predictors Self-efficacy, Belongingness, and Career Goals

Naturvetenskap, teknik, ingenjörsvetenskap och matematik, på engelska ofta grupperade under akronymen STEM, är traditionellt mansdominerade områden. Särskilt inom ingenjörsvetenskap och teknologi är kvinnor fortfarande kraftigt underrepresenterade. Bristen på kvinnor inom STEM innebär utmaningar i att möta arbetsmarknadens behov, för produktkvalitet på grund av brist på olika perspektiv i designprScience, technology, engineering and mathematics, often grouped under the acronym STEM, are traditionally male dominated fields. Especially in engineering and technology, women continue to be heavily underrepresented. The lack of women in STEM poses challenges for meeting the labor market demands, for product quality due to a lack of diverse perspectives in the design process, and for gender equal

Illuminating the Invisible: Green Fluorescent Protein as a Beacon for Antibiotic-Induced Phage Activity in Escherichia coli.

Background/Objectives: Antibiotic resistance presents an urgent public health threat. By developing a streamlined and effective method for studying bacteriophage induction, this research marks a step further in understanding how antibiotic-resistant genes might spread across different environments. This knowledge is essential for creating strategies to reduce the spread of antimicrobial resistanc

* Bone Regeneration Mediated by a Bioactive and Biodegradable Extracellular Matrix-Like Hydrogel Based on Elastin-Like Recombinamers

The morbidity of bone fractures and defects is steadily increasing due to changes in the age pyramid. As such, novel biomaterials that are able to promote the healing and regeneration of injured bones are needed to overcome the limitations of auto-, allo-, and xenografts, while providing a ready-to-use product that may help to minimize surgical invasiveness and duration. In this regard, recombinan

No-one is safe until everyone is safe – patent waiver, compulsory licensing and COVID-19

Recentmonths have seen intensified global calls for an intellectual propertywaiver of COVID-19 related vaccines, treatments and related products.Where one side of the debate elevates Intellectual Property Rights as on obstacle to affordable and expeditious global access to vaccines and treatments, the other side of the debate points to the existing TRIPS flexibilities such as compulsory licensing,

Exploring experiences and coping strategies of the surveillance of indeterminate pulmonary nodules: a qualitative content analysis among participants in the SCAPIS trial.

Objective To elucidate experiences and coping strategies among adults in the surveillance of indeterminate pulmonary nodules detected with CT in the population-based Swedish CardioPulmonary bioImage Study (SCAPIS).Design A qualitative study of conventional content analysis.Settings The study was conducted at a university hospital in a southern region of Sweden. The SCAPIS setting is similar to the