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Vascular mechanical properties and endothelial function with special reference to pregnancy and hormonal influences

Popular Abstract in Swedish Hjärt-kärlsjukdomar är en ledande orsak av sjuklighet och dödlighet. Med hjälp av dagens moderna ultraljudsteknik är det möjligt att påvisa även begynnande, mycket diskreta kärlförändringar. En tidig upptäckt av dessa kan bli av betydelse för individens framtida hälsa. I ett antal studier har vi med hjälp av ultraljud undersökt kärlens styvhet och förmåga att vidgas (enCardiovascular disease (CVD) is one of the leading causes of mortality and morbidity. Early recognition of vascular changes, both structural and functional, may help to identify individuals at risk for CVD. Using modern ultrasound techniques – the echo-tracking technique for assessment of stiffness in large arteries and flow-mediated dilatation of the brachial artery as an indicator of endothelial

A vertebral fracture in childhood is not a risk factor for disc degeneration but for Schmorl's nodes: a mean 40-year observational study.

STUDY DESIGN: Observational cohort study. OBJECTIVE: To evaluate by MRI whether a vertebral fracture during childhood is a risk factor for degeneration of adjacent discs. SUMMARY OF BACKGROUND DATA: Several studies infer that trauma is a major cause of disc degeneration. Only 1 study has by magnetic resonance imaging (MRI) evaluated disc degeneration in children with a former thoracic or lumbar ve

Cigarette smoke extract promotes human vascular smooth muscle cell proliferation and survival through ERK1/2- and NF-κB-dependent pathways.

Tobacco use is one of the major risk factors of cardiovascular disease. The underlying molecular mechanisms that link cigarette smoke to cardiovascular disease remain unclear. The present study was designed to examine the effects of dimethyl sulfoxide (DMSO)-soluble smoke particles (DSPs) on human aortic smooth muscle cell (HASMC) cultures, and to explore the mitogen-activated protein kinase (MAPK

What Drives Exports? Empirical Evidence at the Firm Level

The aim of this thesis is to the understand how firms engage in exporting, particularly in consideration of three aspects—product type, past trade experience, and investments in innovation activities. It consists of one introductory chapter and three independent papers relating to determinants of firms’ exporting. Chapter 2 investigates the distance effect on the exporting of homogeneous and diff

Interacting particles and droplets at low Reynolds numbers

The overall purpose with this work is to study the flow past particles and droplets using numerical simulations. Especially the interaction among particles and droplets have been a main objective as the results are to be used in order to improve already existing spray models. In order to represent the particulate and droplet phase, the Volume of Fluid (VOF) and the Volume of Solid (VOS) methods ar

Hepatocellular Carcinoma Risk Factors and Disease Burden in a European Cohort: A Nested Case-Control Study.

Background: To date, no attempt has been made to systematically determine the apportionment of the hepatocellular carcinoma burden in Europe or North America among established risk factors.MethodsUsing data collected from 1992 to 2006, which included 4 409 809 person-years in the European Prospective Investigation into Cancer and nutrition (EPIC), we identified 125 case patients with hepatocellula

Statliga myndigheters försäljning av fast egendom

Staten äger ett stort antal fastigheter som förvaltas av dels statliga förvaltningsmyndigheter och av dels statligt ägda bolag. Den här rapporten syftar till att utreda innebörden av de regler som de statliga förvaltningsmyndigheterna har att förhålla sig till vid avyttring av fast egendom men den syftar även till att redogöra för den praxis som har utvecklats inom myndigheterna vad gäller försäljThe government holds a large property portfolio, which is managed by governmental administrative authorities and governmental companies. This report aims to investigate the meaning of the rules that the governmental administrative authorities have to follow when they are selling properties, and it also aims to describe the practice that has been developed within the authorities. The report is ba

ePhone och informationsföreläggande

Rättsläget kring implementeringen av IPRED-direktivet har varit osäkert och omtvistat. Förhållandet mellan upphovsrätt och integritet är invecklat och skyddet för de ekonomiska rättigheterna har varit i behov av förbättring samtidigt som att säkrandet av tryggheten för personlig information i ett växande informationssamhälle blivit allt större. Genom domen i ePhone-målet har det fastslagits att dThe legal position regarding the implementation of the IPRED directive has been uncertain and controversial. The relationship between copyright and privacy is complex and protection of the economic rights has been in need of improvement, while the same thing can be argue for safeguarding of the security of personal information in the growing information society. The ruling in the Ephone case has

Do the Customers Matter in Mergers and Acquisitions?

Purpose: The purpose of this study is to examine the relationship between post merger financial performance and customer reactions on M&As, as well as how the issues of strategic relationships, integration, marketing, and human resources influence these customer reactions. Method: One of the main reasons why M&A research lacks so much of customer reactions is that the methodological main

Undersökningsplikten. Säljarens, köparens och mäklarens roll vid köp av fast egendom

En fastighetsaffär är för de allra flesta en stor affär, kanske den allra största man gör i sitt liv, och konsekvenserna kan därför också bli stora, både för köpare och säljare. En av frågeställningarna vid ett köp är ansvarsfördelningen mellan köpare och säljare och det finns många rättsfall genom åren där köparens undersökningsplikt vid köp av fast egendom prövas i svenska domstolar. Enligt JordA property transaction is for most people an important deal, and the impact can therefore also be great, both for buyers and sellers. One of the issues of a purchase is the division of responsibilities for errors between the buyer and the seller, and there are many court cases over the years where the buyer's duty to investigate the purchase of property is tried in Swedish courts. According to

Effective methods for prediction and visualization of contaminated soil volumes in 3D with GIS

Geografiska Informationssystem (GIS) har visat sig vara bra hjälpmedel i projekt för förorenad mark. Idag utvecklas 3D-modellering inom många områden mer och mer. Att kombinera 3D-modellering under markytan med fördelarna med att använda GIS för rumslig data är däremot begränsad. I den här studien har möjligheterna till interpolering av förorenade jordvolymer i 3D undersökts. Studien är fokuserad Geographical Information Systems (GISs) have shown to be of great help in the work at contaminated sites. Today there is an increase in the development of 3D modeling in many fields. However, to combine the advantage working with spatial data in a GIS and 3D modeling for subsurface soil data is limited. In this study, the possibilities of interpolating volumes of soil contamination in 3D were inve

Dödligt skjutvapenvåld: en rättssociologisk studie om betydelsen av gärningspersonernas sociala kontext vid förståelsen av det dödliga skjutvapenvåldet

As a result of the increasing gang criminality, the lethal firearm violence has enhanced since the 1990’s in Sweden which is a development that has in several ways resulted in a social problem. For example are the perpetrator and thereby gang members getting younger, the connection between gang and lethal firearm violence has eventuated in a lower number of solved cases, which is partly due to the

Shaping the role of water : an investigation of participation and stringency in third-party ecolabels for coffee

The global food system, population growth, increased wealth, shifting diets and an overall larger demand for processed food, meat and dairy, has led to increased pressure on land, water and energy. The environmental implications of this have taken part in the establishment of international institutions which aims to regulate agriculture production methods, and thereby reduce these adverse impacts.

BEPS avseende internprissättning och förhållandet till EU-rätten

Den internationella organisationen OECD har tagit fram en omfattande åtgärdsplan, BEPS-projektet, som har till syfte att förhindra att nationella skattebaser eroderas på grund av att internationellt verksamma bolag allokerar beskattningsbara vinster till länder med låga skattesatser. Gränsöverskridande koncerninterna transaktioner är en dominerande metod för att åstadkomma önskad vinstallokering. The international organization OECD has developed a comprehensive action plan, the BEPS project, which aims to prevent national tax bases to erode due to that multinational companies allocate taxable profits in countries with low tax rates. Cross-border intra-group transactions is a predominant method to achieve the desired profit allocation. Transfer pricing rules are therefore a central part of

"There is no life without Jihad"- en kvalitativ studie av IS budskapsstrategier

Idag utgör det självutnämnda kalifatet IS ett av världens mest fruktade och kanske allra kändaste fenomen. Stora militära insatser har initierats med USA i spetsen men samtidigt talar många röster idag dock för att man även bör bemöta IS på andra plan än det militära. IS idéer har fått stor spridning vilket kan härledas till det faktum att gruppen utgör en utvecklad kommunikationsapparat med en stToday the self-proclaimed caliphate IS is one of the most feared and well known phenomenon of its time. Major military operations against the group have been initiated with the United States in the forefront but at the same time expression of opinions argue that IS has to be addressed in other ways than just military. The ideas of IS have been widely spread, this proliferation can be attributed to

New Product Development: Idea Evaluation and the Differences between Ideas having High and Low Levels of Innovation. An Investigation in the Swedish Food Industry

Thesis Purpose: This study has a twofold purpose. First, the authors want to contribute to research on idea evaluation in the fuzzy front end by specifically shedding light on the food industry as this sector differs from other industries (Galizzi & Venturini, 1996; Tidd & Bessant, 2014; Triguero, Córcoles & Cuerva, 2013). Second, different evaluation criteria will be outlined for high

Barn i skyddat boende: personalens perspektiv på barnens situation och föräldraumgänge i fall där barn bevittnat våld i hemmet

Children who witness violence against a parent falls victim to a form of mental abuse. The children often react in fear, anxiety and sadness. Children who witness violence are as much in need of help and support as those children who are themselves victims of violence. A person who is subjected to violence by their partners in Sweden have an opportunity to seek protection. With the help of social

Rullflaskemetoden

Abstract Today large amounts of macadam are being delivered for the production of asphalt. One of the requirements of the material that´s being used is the adhesion. The adhesion is essential for the performance of the coating. It minimizes the risk of stone chips and makes the construction of the pavement stronger etc. Several studies have been made using the Roller bottle method. The results sho