Filtyp
The hub and main characteristic of Islamic banking is the prohibition of interest (riba), and this is the most significant difference between an Islamic bank and a conventional bank. The proscription has evolved from the stance that making money from money is unacceptable. Riba is often referred to as interest and usury, but it has often been disputed whether the expression involves both terms. Ne
In the last couple of years the lack of housing and homelessness has increased in Malmö. At the same time there has been a discussion about the importance of housing as a part of the aftercare related to social work. Malmö has a goal stating that people that have stayed in hospital, treatment or served a prison sentence shall be offered a drug-free housing with a personalized support. We were inte
Sammanfattning Den kanske största miljöpolitiska utmaningen inom Europa är för närvarande frågan om hur det är möjligt att på ett effektivt och ändamålsenligt sätt uppnå miljömålen i syfte att skapa en hållbar utveckling i samhället. Trenden har gått från att tillgripa lagstiftningsåtgärder till att via marknadsbaserade styrmedel försöka involvera olika marknadsaktörer att på egen hand bli delaktSummary Potentially one of the greatest environmental policy challenges in the European Union is the question of how to efficiently and effectively achieve environmental goals through which society can correct for and obtain a level of sustainable development. The trend has gone from one of command and control legislation towards using more market-based instruments that seek to involve the differ
Growth hormone (GH) has insulin-antagonistic effects, and GH secretion is augmented during fasting and hypoglycemia. In the present study, 10 patients aged 21 to 28 years with childhood-onset GH deficiency (GHD) were studied during a 24-hour fast and a hypoglycemic glucose clamp before and after 9 months of GH replacement. During the 24-hour fast, blood glucose, serum insulin, and serum free fatty
BACKGROUND: Cancer has consequences not only for the sick person but also for those who have a close relationship with that person. Greater knowledge about how family members manage the situation in the period immediately following the diagnosis means greater opportunity to provide the best possible support for the family. The purpose of this study was to explore management strategies that family
The "type" DeKalb mounds of northeastern Illinois, USA (42.0 degrees N, -88.7 degrees W), are formed of basal sand and gravel overlain by rhythmically bedded fines, and weathered sand and gravel. Generally from 2 to 7 m thick, the fines include abundant fossils of ostracodes and uncommon leaves and stems of tundra plants. Rare chironomid head capsules, pillclam shells, and aquatic plant macrofossi
Background: Many patients with aggressive B-cell lymphomas and high clinical risk score still die of lymphoma after conventional R-CHOP chemoimmunotherapy. We hypothesized that intensified chemoimmunotherapy including systemic central nervous system (CNS) prophylaxis improves outcome and reduces the incidence of CNS-related events. Patients and methods: Inclusion criteria were age 18-65 years, pri
Modern industrial robots are traditionally programmed to follow desired trajectories, with the only feedback coming from the internal position/angle sensors in the joints. The robots are in general very accurate in tracking the desired motion, and they have become indispensable in many applications, such as spot welding and painting in the automotive industry. In more complex tasks, such as physic
Although estrogen receptor-alpha (ERalpha) is a marker used to identify breast cancer patients most likely to benefit from endocrine therapy, approximately 50% of ERalpha-positive breast carcinomas are resistant to tamoxifen. Preclinical studies have shown that phosphorylation of ERalpha at serine-118 (ERalphaS118-P) is required for tamoxifen-mediated inhibition of ERalpha-induced gene expression.
Natural enemies exert selection pressure on their prey. Predators and parasitoids drive their prey into the evolution of novel traits to cope with this stress. When eggs and juveniles are the target of enemies, defense strategies may rely on adults. However, it is not easy to predict whether adults should actively protect unrelated offspring. Females of the golden egg bug (Phyllomorpha laciniata)
The introduction of L-DOPA pharmacotherapy revolutionized the treatment of Parkinson’s disease close to fifty years ago. Before the discovery of dopamine as a neurotransmitter and its involvement in the disease, these patients had very little aid from medication and were bound to a life without movement. The dopamine neurons in the midbrain are a key player in the circuitry that is responsible for
Glacifluvial deposits along an ice-marginal zone,in Smaland, southern Sweden, have been dated using post-IR blue OSL. To test for incomplete bleaching, we adopted two strategies: analysis of modern analogues and small-aliquot dose distributions. Samples of modern fluvial sediments show no significant incomplete bleaching; they yield equivalent doses of only 0.5-2 Gy (similar to 0.25-4% of our glac
As oil-prices and environmental concerns are increasing, it is of interest to better use the well-head gas. This light fraction co-produced with petroleum is generally flared and in this paper a method for upgrading and returning the co-product to the petroleum stream is suggested. The method is based on a conversion of the gas to synthesis gas and upgrading this synthesis gas into liquid hydrocar
Protein adsorption is a complex process that it controlled by several different mechanisms, for example: (i) electrostatic interactions between the protein and the surface, and (ii) between adsorbed proteins; (iii) dispersion interactions; (iv) hydration effects; and (v) structural rearrangements of the protein to balance conformational chain entropy with energetics. The aim of this study was to d
Background and aims: Lipids are needed for optimal glucose-stimulated insulin secretion (GSIS), and long-chain acyl-CoA (LC-CoA) has been suggested as one candidate molecule active as a lipidic coupling factor. LC-CoAs may be available to the beta-cell via uptake of circulating free fatty acids or from hydrolysis of intracellularly stored triglycerides. Inhibition of lipolysis in rat islets using
This study systematically analyzes platelet-derived growth factor (PDGF) receptor expression in six types of common tumors as well as examines associations between PDGF beta-receptor status and clinicopathological characteristics in breast cancer. PDGF receptor expression was determined by immunohistochemistry on tumor tissue microarrays. Breast tumor data were combined with prognostic factors and
It has long been recognised that dispersal abilities and environmental factors are important in shaping invertebrate communities, but their relative importance for primary soil community assembly has not yet been disentangled. By studying soil communities along chronosequences on four recently emerged nunataks (ice-free land in glacial areas) in Iceland, we replicated environmental conditions spat
Early initiation of everolimus with calcineurin inhibitor therapy has been shown to reduce the progression of cardiac allograft vasculopathy (CAV) in de novo heart transplant recipients. The effect of de novo everolimus therapy and early total elimination of calcineurin inhibitor therapy has, however, not been investigated and is relevant given the morbidity and lack of efficacy of current protoco
The prototypical antimicrobial peptide, melittin, is well-known for its ability to induce pores in zwitterionic model lipid membranes. However, the mechanism by which melittin accomplishes this is not fully understood. We have conducted all-atom and coarse-grained molecular dynamics simulations which suggest that melittin employs a highly cooperative mechanism for the induction of both small and l
Aims: To evaluate outcome in the first generation of children with end-stage heart disease to whom heart transplantation was available. Methods: Retrospective review of all 135 Swedish children <18 years old listed for heart transplantation 1989-2009, followed to December 31, 2009, including 74 (55%) with cardiomyopathy and 61 (45%) with congenital heart disease; 34 (25%) were infants (<1 year). C
