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BACKGROUND: Patients with new-onset atrial fibrillation in relation to infection are frequent in emergency departments (ED) and may require antithrombotic therapy due to increased risk of stroke. Our objective was to describe the one-year risk of stroke in ED patients with infection, new-onset atrial fibrillation and no antithrombotic therapy.METHODS: Population-based cohort study at four EDs in D

A 2H n.m.r. relaxation study of sodium dodecyl sulphate (SDS) in the micellar phase is presented. The surfactant is specifically deuterated in the α-, γ- and ω-positions. Relaxation data are obtained at two temperatures and at three field strengths, and show a dependence on the field strength. The data are analysed with the 'two-step' model of relaxation, and the fast correlation times as well as

Background: Bisphosphonates have previously been shown to increase the density of impacted graft bone. In the present study we hypothesise that bisphosphonates also reduce early stem subsidence. We examined the effect of locally applied bisphosphonate to allografts on prosthetic micromotion and bone density in femoral stem revision with impaction grafting. Methods: 37 patients were randomised to e

Within the hematopoietic system, the Notch pathway is critical for promoting thymic T cell development and suppressing the B and myeloid lineage fates; however, its impact on NK lymphopoiesis is less understood. To study the role of Notch during NK cell development in vivo, we investigated different NK cell compartments and function in Rbp-Jkfl/flVav-Cretg/+ mice, in which Rbp-Jk, the major transc

Glucagon is the principal glucose-elevating hormone that forms the first-line defence against hypoglycaemia. Along with insulin, glucagon also plays a key role in maintaining systemic glucose homeostasis. The cells that secrete glucagon, pancreatic α-cells, are electrically excitable cells and use electrical activity to couple its hormone secretion to changes in ambient glucose levels. Exactly how

The Sagittarius dwarf spheroidal (Sgr dSph) galaxy is currently being accreted and disrupted by the tidal field of the Milky Way. Recent observations have shown that the central region of the dwarf hosts at least three different stellar populations, ranging from old and metal-poor over intermediate metal-rich to young metal-rich. While the intermediate-age metal-rich population has been identified

The sixth volume in the Interdisciplinary European Studies assesses the changes that are taking place in the EU’s policies, institutions, and political structures. On the eve of a new chapter of European integration in the dark shadow of the war in Ukraine, it is high time to assess the changes that have taken place in recent time and consider whether current developments are taking the EU on the

This chapter provides a succinct overview of the rapidly developing field of scholarship on far-right manifestations across Europe from a gendered perspective. Its starting point is to acknowledge that gender plays a crucial role in grasping the ideological underpinnings and the modus operandi of the various entities, which are generally associated with the larger field of socio-political manifest

The paper deals with numerical investigations of load-bearing capacity and fracture behaviour of Cross Laminated Timber at in-plane shear loading. Focus is on shear failure mechanism III, i.e. failure in the crossing areas between flatwise bonded laminations, and on evaluating test methods for that failure mode. In current design provisions, this failure mode is characterised by the rolling shear

Symmetry-breaking charge separation in molecular materials has attracted increasing attention for optoelectronics based on single-material active layers. To this end, Fe(III) complexes with particularly electron-donating N-heterocyclic carbene ligands offer interesting properties with a 2LMCT excited state capable of oxidizing or reducing the complex in its ground state. In this Communication, we

Prognostic tools are an essential component of the clinical management of patients with renal cell carcinoma (RCC). Although tumour stage and grade can provide important information, they fail to consider patient- and tumour-specific biology. In this study, we set out to find a novel molecular marker of RCC by using hepatocyte nuclear factor 4A (HNF4A), a transcription factor implicated in RCC pro