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Effect of headgroup on DNA - Cationic surfactant interactions

The interaction behavior of DNA with different types of hydroxylated cationic surfactants has been studied. Attention was directed to how the introduction of hydroxyl substituents at the headgroup of the cationic surfactants affects the compaction of DNA. The DNA-cationic surfactant interaction was investigated at different charge ratios by several methods like UV melting, ethidium bromide exclusi

IL-10-deficient B10.Q mice develop more severe collagen-induced arthritis, but are protected from arthritis induced with anti-type II collagen antibodies

IL-10 is a pleiotropic cytokine with stimulatory and inhibitory properties, and is thought to have a protective role in rheumatoid arthritis and collagen-induced arthritis (CIA). In this study, we investigated how IL-10 deficiency affects CIA and anti-collagen type II (CII) Ab-transferred arthritis in C57BL/10.Q (B10.Q) mice. The B10.Q.IL-10(-/-) mice had an 8-cM 129/Ola fragment around the IL-10

Characterization of Lyme borreliosis isolates from patients with erythema migrans and neuroborreliosis in southern Sweden

Southern Sweden is an area of Lyme borreliosis (LB) endemicity, with an incidence of 9 cases per 100,000 inhabitants. The most frequent clinical manifestations are erythema migrans (77%) and neuroborreliosis (16%). There was no record of human Borrelia strains being isolated front patients in this region before the prospective study reported here. Borrelia spirochetes were isolated from skin and c

A calorimetric study of phospholipid hydration. Simultaneous monitoring of enthalpy and free energy

We present a novel method for monitoring isothermal lipid hydration using a sorption microcalorimeter. A measuring cell of the double-twin calorimeter consists of two vessels connected by a stainless steel tube. The upper vessel contains pure water, and the bottom vessel is loaded with the lipid sample. This calorimeter allows for simultaneous measurement of the partial molar enthalpy and the chem

Blue intensity and density from Northern Fennoscandian tree rings, exploring the potential to improve summer temperature reconstructions with earlywood information

Here we explore two new tree-ring parameters, derivedfrom measurements of wood density and blue intensity(BI). The new proxies show an increase in the interannualsummer temperature signal compared to establishedproxies, and present the potential to improve long-term performance.At high latitudes, where tree growth is mainlylimited by low temperatures, radiodensitometric measurementsof wood density

A Descriptive Study of Bacterial Load of Full-Thickness Surgical Wounds in Dermatologic Surgery.

BACKGROUND Surgical site infections (SSIs) after dermatologic surgery cause pain, prolong healing, result in unaesthetic complications, and lead to excessive use of antibiotics. The pathogenesis of wound infections is complex and is dependent on bacterial load and diversity, among several factors. OBJECTIVE To investigate bacterial dynamics at dermatosurgical sites at different time intervals and

Achieving Urban Resilience: Understanding and Tackling Disasters from a Local Perspective

The damage caused by a dramatic worldwide increase in so-called natural disasters is staggering, with the poor in developing countries being most at risk. This paper analyses: (a) the key variables and their causal relations that underlie the complex system of risk and disaster occurrence in slums; (b) the impacts of disasters on slums; (c) the strategies used by local people to cope with risk and

The importance of major histocompatibility complex class II genes for the development of autoimmune inflammation

Popular Abstract in Swedish Genetisk påverkan i ledgångsreumatism Ett väl fungerande immunsystem är en förutsättning för kroppens kamp mot diverse sjukdomar orsakade av t ex virus och bakterier. En grundläggande egenskap hos immunsystemet är dess förmåga att skilja på vad som är kroppens egna celler och molekyler och vad som är främmande. Ibland fungerar inte denna diskriminering som den ska och In this thesis the role of major histocompatibility complex (Mhc) class II molecules in development of autoimmune disease such as rheumatoid arthritis (RA), was studied. By combining an experimental model for RA, collagen type II induced arthritis (CIA), with molecular biology methods the importance of polymorphism in Mhc class II genes for disease development was investigated. The Mhc region con

Phototoxicity

Phototoxicity occurs when a substance is toxic only under the action of light, and can, depending on the mechanism of toxic action, be divided into type I and type II phototoxicity. Other types are sometimes recongnized, and sometimes toxicity occurs through more than one mechanism. Plants often use phototoxins for their defense. They may be harmful to man, but also exploited for medical treatment

Patch antennas based on a pair of DPS and SNG metamaterial

In this talk we show some potential applications of a pair of conventional double positive (DPS) and single negative (SNG) metamaterial blocks for specific patch antennas. We propose two designs. One is a 900- and 1800-MHz dual-band rectangular patch antenna filled with a pair of juxtaposed DPS and mu-negative (MNG) metamaterial blocks. With proper constitutive parameters and filling ratio of the

Feedback Scheduling of Control Tasks

The paper presents a feedback scheduling mechanism in the context of co-design of the scheduler and the control tasks. We are particularly interested in controllers where the execution time may change abruptly between different modes, such as in hybrid controllers. The proposed solution attempts to keep the CPU utilization at a high level, avoid overload, and distribute the computing resources eve

Creaky fillers and speaker attitude: data from Swedish

Spontaneous data from Swedish are presented which suggest that ‘creaky voice’ associated with the filler EH ‘UH’ is related to the realization of the speaker attitude ‘uncertainty’ in the sense of ‘indecisiveness’ as regards the optimal way to linguistically code referents and predicates. It is suggested that creaky fillers express a certain degree of speaker indecisiveness as regards the most rel

Community and food web assembly on virgin habitat islands - The nunatak saga

Popular Abstract in Icelandic Landnám á jökulskerjum Plöntur hafa lengi verið taldar nauðsynlegar til að dýr geti numið land en þessi sýn er að breytast því rannsóknir hafa sýnt að smádýr nema oft land á undan plöntum. Landnám bæði plantna og dýra getur hafist um leið og nýtt land myndast en til að landnám takist þurfa nokkrir þættir að fara saman. Þau verða að komast á staðinn og þegar þangað erThe classical view of primary community assembly is that colonisation by plants is essential before invertebrates can establish. It has been recognised, however, that invertebrates can establish before plants, and that they may be important in the first steps of community assembly. Plant succession is well studied but assembly of invertebrates and how their dispersal abilities affect the community

First steps towards a computational theory of autism

A computational model with three interacting components for context sensitive re-inforcement learning, context processing and automation can autonomously learn a focus attention and a shift attention task. The performance of the model is similar to that of normal children, and when a single parameter is changed, the performance on the two tasks approaches that of autistic children.