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Sternal opening width is associated with increased risk for capillary leak syndrome and death in neonates and infants after cardiac surgery with delayed sternal closure

Capillary leak syndrome is a serious postoperative complication in neonates and infants after open-heart surgery for CHD. The aim of this study was to investigate the relationship between sternal opening width and the occurrence of capillary leak syndrome in patients undergoing cardiac surgery with delayed sternal closure.We retrospectively analysed the clinical data of neonates and infants (aged

Det intellektuella kapitalet - Hur hanterar företag dessa viktiga tillgångar?

Då det intellektuella kapitalet utgör en viktig del av ett företags totala tillgångar, har vi valt att undersöka hur hanteringen och styrningen av detta kapital ser ut i verkligheten. Dessutom ville vi se om våra undersökningsföretag skulle kunna förbättra sin hantering av IK genom att tillämpa de modeller som finns på området. De modeller vi valt att titta närmare på är Skandia Navigator, The Int

Key Role of flt3 Ligand in Regulation of the Common Lymphoid Progenitor but Not in Maintenance of the Hematopoietic Stem Cell Pool.

The first lineage commitment step of hematopoietic stem cells (HSC) results in separation into distinct lymphoid and myeloid differentiation pathways, reflected in the generation of common lymphoid and myeloid progenitors (CLP and CMP, respectively). In this report we present the first evidence for a nonredundant regulator of this process, in that adult mice deficient in expression of the flt3 lig

Red giant depletion in globular cluster cores

We investigate the observed depletion of red giants in the cores ofpost-core-collapse globular clusters. In particular, the evolutionaryscenario we consider is a binary consisting of two low-mass stars whichundergoes two common-envelope phases. The first common-envelope phaseoccurs when the primary is a red giant resulting in a helium white dwarfand main-sequence star in a detached binary. The sec

Effects of complement regulators bound to Escherichia coli K1 and Group B Streptococcus on the interaction with host cells

Escherichia coli K1 and Group B Streptococcus (GBS) are the most common bacteria that cause meningitis during the neonatal period. Complement, the first line of defence in the host, acts on these bacteria to opsonize with various components of complement for subsequent presentation to phagocytes. To counteract these opsonization effects, E. coli and GBS bind to the complement regulators C4 binding

Mouse models for rheumatoid arthritis

Rheumatoid arthritis (RA) affects millions of people world wide causing considerable human suffering and large socioeconomic costs. Increased knowledge of pathological pathways involved in RA will enable development of modern drugs, with reduced side effects. The mouse models offer an attractive approach to dissect the genetic and molecular mechanisms of RA.

Single-step purification of human C4b-binding protein (C4BP) by affinity chromatography on a peptide derived from a streptococcal surface protein.

Many Gram-positive bacteria express surface proteins that bind human plasma proteins. These bacterial proteins, and derivatives of them, are of interest for analysis of bacterial pathogenesis and as immunochemical tools. Well-characterized examples include the IgG-binding reagents staphylococcal protein A and streptococcal protein G, and the recently described streptococcal IgA-binding peptide Sap

Ab initio MP2 and DFT study of the thermal Syn elimination reaction in ethyl formate

The thermal elimination reaction that appears in some polycarbonates has been studied by density functional theory (DFT) and ab initio methods of different levels. This work has been focused in the elimination process of ethyl formate, as a good model of this kind of reaction. Different minima and the transition state have been found to characterize the thermal elimination reaction, and the activa

Rayleigh adjustment of narrow barriers in protoplanetary discs

Sharp density features in protoplanetary discs, for instance at the edge of a magnetically dead zone, have recently been proposed as effective barriers to slow down or even stop the problematically fast migration of planetary cores into their central star. Density features on a radial scale approaching the disc vertical scaleheight might not exist, however, since they could be Rayleigh (or more ge