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Pulsar binaries are important targets for ground-based and future space-borne gravitational-wave (GW) detectors. In order for improving detector design and assessing detector performances, it is a prerequisite to understand the astrophysics of GW sources such as the population size or merger rates. Here, we summarize recent results for Galactic merger rates of two known types of pulsar binaries: (
This chapter describes a personal aerosol sampler with size fractionation and time resolution that gives samples for elemental analysis. An impaction stage collects coarse particles and a filtration stage collects finer ones. Sampling in consecutive time intervals is performed on different impaction and filtration surfaces. These sampling surfaces corresponding, for example, to 15-min intervals, m
There is a need for analytical methods capable of monitoring blood antibiotic levels in real time. Here we present a method for quantifying antibiotic levels in whole blood that does not require any sample pretreatment. The tests employ the enzyme penicillinase to assay for penicillin G, penicillin V and ampicillin using a flow-injected biosensor, the Enzyme Thermistor. Optimal flow rates, sample
Hos 11,8-9 is characterized by its strong anthropomorphic language and by its (illusory?) disassociation from it. A reference to Israel’s God as “not human” motivates the unexpected change of mind and compassion for God’s Israel. This article is based on a tradition-historical oriented typological reading of the expression “I am God and not human.” It suggests a new interpretation of this expressi
Laser-induced Rayleigh scattering is commonly employed for two-dimensional temperature measurements and offers benefits such as high accuracy, easily interpreted data and low experimental complexity. Yet the approach suffers from an interference often referred to as stray light, an umbrella term used for all spurious light being detected. As Rayleigh scattering is an elastic scattering phenomenon,
In Elder-Vass’s response to my (2014) it is maintained: (1) that a social object is not identical with but is merely composed of its suitably interrelated parts; (2) that a social object is necessarily indistinguishable in terms of its causal capacities from its interrelated parts; and (3) that ontological individualism lacks an adequate ontological justification (Elder-Vass forthcoming). In this
Introduction. Anti-neutrophil cytoplasmic antibodies specific for bactericidal/permeability-increasing protein (BPI-ANCA) are frequent in CF patients and mainly develop in response to infection with Pseudomonas aeruginosa. It is not known to what extent BPI-ANCA correlates to prognosis. Objectives. To evaluate the prognostic value of IgA-BPI-ANCA, measured at the beginning of the study, for transp
Cell surface proteins that bind to the Fc part of immunoglobulin (Ig) A and/or IgG are expressed by many strains of the group A Streptococcus, an important human pathogen. Two extensively characterized proteins in this group of molecules are protein Arp that preferentially binds IgA and protein H that binds IgG. In addition, recent work has shown that many group A streptococcal strains express a n
Cosmological long-duration gamma-ray bursts (LGRBs) are thought to originate from the core collapse to black holes (BHs) of stripped massive stars. Those with sufficient rotation form a centrifugally supported torus whose collapse powers the GRB. We investigate the role of tidal locking within a tight binary as a source of the necessary angular momentum. We find that the binary orbit must be no wi
Purified, recombinant M12 protein from Streptococcus pyogenes CS24 has recently been demonstrated to bind human immunoglobulin G3 (IgG3). The binding site for IgG has been localized to an internal peptide encoded by a PvuII fragment of the gene emm12. We have investigated the ability of an isolated recombinant M12 protein consisting of the peptide encoded by the PvuII fragment to bind various mono
Positional cloning of the underlying genes for the rare syndrome autoimmune polyendocrinopathy candidadiasis extrodermal dystrophy (APECED) opened a new venue of research on the role of central tolerance in autoimmunity. The associated autoimmune regulator gene (AIRE), was found to be expressed in medullary thymus epithelial cells (mTEC) in both man and mice, and to control promiscuous expression
Early B cell factor (EBF)-1 is a transcription factor known to be of critical importance for early B lymphocyte development. EBF-1 has been shown to directly interact with and regulate expression of a set of genes involved in the functional formation of the preB cell receptor, but the dramatic phenotype observed in the EBF-1-deficient mice suggests that several additional genes are activated by th
The gene for protein D, a membrane-associated protein with specific affinity for human immunoglobulin D, was cloned from a nontypeable strain of Haemophilus influenzae. The gene was expressed in Escherichia coli from an endogenous promoter, and the gene product has an apparent molecular weight equal to that of H. influenzae protein D (42,000). The complete nucleotide sequence of the gene for prote
A technique of fluorescence multiplexing is described for analysis of the plasma membrane proteome of colorectal cancer cells from surgically resected specimens, enabling detection and immunophenotyping when the cancer cells are in the minority. A single-cell suspension was prepared from a colorectal tumour, and the mixed population of cells was captured on a CD antibody microarray. The cancer cel
BACKGROUND: Asthma guidelines recommend that long-acting inhaled beta-agonists should be used as maintenance therapy for patients with asthma inadequately controlled on an inhaled corticosteroid. We studied the safety and efficacy of the long-acting beta-agonist formoterol compared with terbutaline, each taken as needed, in patients with moderate to severe asthma. METHODS: Patients were taking an
