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Popular Abstract in Swedish Immunsystemet skyddar oss mot de patogener (t ex bakterier eller virus) som vi dagligen utsätts för. Det består av flera olika samtidigt verkande system. De enklare består av vår hud och de olika slemhinnor som finns till exempel i halsen och i tarmsystemet. Vidare finns det olika typer av celler och blodproteiner som kan skydda oss mot många infektioner. Det mest utvecThis thesis focuses on molecular changes occuring during terminal B cell differentiation as well as on somatic hypermutation and the generation and maintenance of B cell memory. During T cell dependent immune responses the average affinity for the eliciting antigen increases with time. This affinity maturation is generated by somatic hypermutation and selection for B cells carrying a high-affinty

Background and purpose — Backside wear of the polyethylene insert in total knee arthroplasty (TKA) can produce clinically significant levels of polyethylene debris, which can lead to loosening of the tibial component. Loosening due to polyethylene debris could theoretically be reduced in tibial components of monoblock polyethylene design, as there is no backside wear. We investigated the effect of

In this work, 22 sets of cutting data and tool life for longitudinal turning of steel are analyzed using the Colding equation. When modeling tool life with a limited number of tool performance data points, the model error may be low for these points. Evaluating the model for test points not used when computing the model coefficients may give larger errors for these points. This work proves that th

This paper describes an ascending evacuation model based on physical work capacity, when exhaustion may play a key role during evacuation. The experiment was carried out on a stair machine (StairMaster, SM5, USA) which involved 13 male and 12 female subjects. Individual climbing speeds at 50 and 70 % of their maximal aerobic capacity (% VO2max) level (L1 and L2) were selected for 3 minutes, and 90

This study attempts to apply computational methods to the Twitter Election Integrity Datasets in order to derive a basic descriptive overview of this disinformation data, and to suggest some possible routes for developing these methods to address future research questions. The results indicate substantial variations in tweet frequency over time and geographical regions, as well as differences in r

Within cognitive science, “blindness” to choice is commonly treated as typical of human cognition, implying unreliable agents who essentially lack any awareness of their own choices (e.g. Johansson et al., 2005, 2008; Hall et al., 2010, 2013). Within cognitive semiotics, however, choice awareness is seen as a continuous phenomenon, which is susceptible to the influence of a variety of factors. Man