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A non-affine micro-sphere formulation for electroactive polymers
Identification of Application Specific Instructions Based on Sub-Graph Isomorphism Constraints
Everyday student resistances in the Kurdish region of Iraq
Comparison of the image rejection between the passive and the Gilbert mixer
This paper presents a comparison of the image rejection between Gilbert mixer and the passive mixer. A simple model for mixers is set up, and the image rejection performance of passive and Gilbert mixer is analyzed based on it. Simulations and calculations were done to compare the image rejection of the two mixers. The results show that the Gilbert mixer, comparing with the passive one, shows a st
Towards an Information Systems Design Research Framework: A Critical Realist Perspective
Design of an Antibody Library Biased for Haptens
Accessibility, usability and universal design – positioning and definition of concepts describing person – environment relationships
The story of bioCEED or how to grow a SoTL culture from scratch
Modelling multi-scale deformation of amorphous glassy polymers with experimentally motivated evolution of the microstructure
Novel experimental data, obtained recently using advanced multi-scale experiments, have been used to develop a micro-mechanically motivated constitutive model for amorphous glassy polymers. Taking advantage of the experiments, the model makes use of a microstructural deformation gradient to incorporate the experimentally obtained deformation of the microstructure, as well as its evolving orientati
Genetics of Immune Disease
Mesenchymal Stem Cells
Measuring Antibody Orientation at the Bacterial Surface
Many bacteria have the ability to interact with antibodies as a means to circumvent the immune response. This includes binding to the Fc portion of antibodies, effectively reversing the antibody orientation and thus decreasing the Fc-mediated immune signaling. Since antibody orientation at the bacterial surface has been shown to be important in human disease, it is valuable to be able to assess ho
Lateral Protein-Protein Interactions at Hydrophobic and Charged Surfaces as a Function of pH and Salt Concentration
Surface adsorption of Thermomyces lanuginosus lipase (TLL) - a widely used industrial biocatalyst - is studied experimentally and theoretically at different pH and salt concentrations. The maximum achievable surface coverage on a hydrophobic surface occurs around the protein isoelectric point and adsorption is reduced when either increasing or decreasing pH, indicating that electrostatic protein-p
On PAMPs and DAMPs
Evidence for PKA-independent priming of insulin secretory granules: insight from mathematical modeling
Report of an international survey of molecular genetic testing laboratories
Objective: To collect data on the practices of molecular genetic testing (MGT) laboratories for the development of national and international policies for quality assurance (QA). Methods: A web-based survey of MGT laboratory directors (n = 827; response rate 63%) in 18 countries on 3 continents. QA and reporting indices were developed and calculated for each responding laboratory. Results: Laborat
Identification of a strongly activating human anti-CD40 antibody that suppresses HIV-1 infection
We characterized the functional properties of a novel set of human anti-CD40 monoclonal antibodies originating from a human phage display library and identified an antibody that strongly activates cells via the CD40 receptor for potential use in HIV therapy. The anti-CD40 antibodies were converted from a single chain antibody fragment format (scFv) to an IgG format and produced in HEK293 cells, an
The experiences of older people living with cancer
Nursing care for older people with cancer requires an understanding of their history and current needs from both an individual and generalized view. The aim of this study was to investigate the experience of older people living with cancer and the way it affects their daily life. During the study, 41 individuals 75 years of age and older (mean age, 83 years) who had a cancer diagnosed within the p
