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A divalent antibody format is required for neutralization of human cytomegalovirus via antigenic domain 2 on glycoprotein B

Glycoprotein B (gB) of human cytomegalovirus (HCMV) is the dominating protein in the envelope of this virus and gives rise to virus-neutralizing antibodies in most infected individuals. We have previously isolated a neutralizing human antibody specific for antigenic domain 2 (AD-2) on gB, a poorly immunogenic epitope, which nevertheless is capable of eliciting potent neutralizing antibodies. In or

AOSIS förhandlingsmakt på FN:s klimatmöten

Besluten som tas på FN:s årliga klimatmöten (COP) påverkar hela världen. De som påverkas mest, det vill säga drabbas först och hårdast av klimatförändringarna är världens små ö-stater. Dessa små ö-stater har gått ihop i en koalition som heter Alliance of Small Island States (AOSIS) som representerar dem i FN:s klimatförhandlingar. Det vi är intresserade av är att se vilken makt AOSIS har att påver

The Phonology of Mongolian

This book provides (a) the first comprehensive description of the phonology and phonetics of Standard Mongolian, known as the Halh (Khalkha) dialect and spoken in Ulaanbaatar, the capital of the Republic of Mongolia; and (b) the first account in any language of the historical phonology of the Mongolian group of languages. The synchronic phonology is based on data collected by the authors and on th

Visible and radar observations of the Perseid meteor stream 1953-83

This paper describes a long term, high-resolution study of the activityof the Perseid meteor stream based on visual and radar observations atthe Onsala Space Observatory in Sweden. The data consists of 147 visualhourly rates and 1368 radar hourly rates. In a previous paper (Lindblad2000) a high-resolution study of the visual zenithal hourly rates ofbright Perseid meteors versus solar longitude was

Laplace model for multi-axial responses in fatigue analysis of a cultivator frame

This paper reviews means for fatigue damage rates estimation using Laplace distributed multiaxial loads. The model is suitable for description of stresses containing transients of random amplitudes and locations. Explicit formulas for computing the expected value of rainflow damage index as a function of excess kurtosis are given for correlated loads. A Laplace model is used to describe variabilit

Självbiografier och dagböcker

En översikt över dagboksskrivandets och det självbiografiska skrivandets roll,typer och funktio under svenskt 1700-tal. Särskilt intresse ägnas den kristna traditionens betydelse för introspektion och subjektsuppfattning.

Rational unified process (RUP) and its relationship with the end-user in the software system development process

The user-centered design or usability design or human computer interaction there are very close or similar concept, and a very wide subject of study. The Rational Unified Process is very complex by itself. There are many criticisms again The Rational Unified process because it is alleged lack of tools and helps in the user-centered development. Relating these areas by finding out the relationships