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Star scientists as drivers of the development of regions

This chapter investigates the location pattern (at the NUTS 2 level) of European-based star scientists (identified by the number of citations they generated in journals in the ISI database) as well as the degree and intensity of knowledge sharing activities performed by the scientific elite in their regions of choice. Using a unique dataset of 197 star scientists, we demonstrate that Europe’s worl

Development of adaptive kinetics for application in combustion systems

In this paper, an automatic method for reducing chemical mechanisms during run time based on the quasi-steady-state assumption (ASSA) is presented. The method uses a lifetime analysis of the chemical species which can be set to steady state according to a ranking procedure. Steady-state species concentrations are computed by algebraic rather than differential equations, thus yielding a significant

Temporal and spatial variation of hematozoans in Scandinavian willow warblers

We examined temporal and geographical distribution of Haemoproteus sp. and Plasmodium sp. parasites in Swedish willow warblers, Phylloscopus trochilus. Parasite lineages were detected with molecular methods in 556 birds from 41 sites distributed at distances up to 1,500 km. Two mitochondrial lineages of Haemoproteus sp. were detected, WW1 in 56 birds and WW2 in 75 birds, that differed by 5.2% sequ

Comparison between comparative tuberculin and gamma-interferon tests for the diagnosis of bovine tuberculosis in Ethiopia

A study to determine and compare the sensitivities and specificities of the comparative cervical tuberculin (CCT) and gamma-interferon (IFN-gamma) tests for the diagnosis of bovine tuberculosis was conducted on 30 zebu oxen. The results of the tests were compared with the presence of acid-fast bacilli found by bacteriological culturing and histopathological examinations. The sensitivity and specif

Isolation of obligate anaerobic rumen bacteria capable of degrading the neurotoxin beta-ODAP (beta-N-oxalyl-L-alpha,beta-diaminopropionic acid) as evaluated by a liquid chromatography/biosensor analysis system

Six pure strains of obligate anaerobes capable of degrading the toxin beta-N-oxalyl-L-alpha, beta-diaminopropionic acid (beta-ODAP) contained in grass pea (Lathyrus sativus) have been isolated from cow rumen. The new isolates were identified as Megasphaera elsdenii (five different genotypes) and Clostridium bifermentans using 16S rDNA analysis. The beta-ODAP degrading efficiency of the isolates wa

Binding Characteristics Determine the Neutralizing Potential of Antibody Fragments Specific for Antigenic Domain 2 on Glycoprotein B of Human Cytomegalovirus

Site I of antigenic domain 2 (AD-2) on human cytomegalovirus glycoprotein B (gB) is poorly immunogenic in both man and mouse and knowledge about antibody repertoires reactive with this epitope is thus limited. Here we have characterized a phage display-derived repertoire of antibody fragments specific for this epitope in terms of antigen recognition, fine-specificity, and virus-neutralizing capaci

Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines

The nuclear receptor peroxisome proliferator-activated receptor delta [PPARdelta/beta (NR1C2)] has been implicated in colorectal carcinogenesis by various molecular genetic observations. These observations have recently been supported by studies of activation of PPARdelta by pharmacological agents. Here we present the first report of the stimulation of breast and prostate cancer cell growth using

Fatty-acid-displaced transcriptional repressor, a conserved regulator of cytochrome P450 102 transcription in Bacillus species

Bacillus subtilis strain 168 encodes two flavocytochromes P450, Cyp102A2 and Cyp102A3. The cyp102A3 gene is preceded by, and organized in an operon with, a gene for a transcriptional regulator, encoded by fatR. The paralogous gene, cyp102A2, is most likely transcribed as a mono-cistronic message. We show that fatR encodes a protein that binds to an operator sequence that is present upstream of its

Galectin-8 specificity to cells: from broad outside to fine inside

Glycobiology is the world of sugars: how they are made, what they look like, and what they do. Despite the importance of glycan structures in life, knowledge has been hampered due to their inherent complexity. Lectins are nature's way to decipher the intricate code held by glycans, which makes them important players in both normal and pathological physiology. A key to the understanding of lectins

Interactions between Sulfide Minerals and Alkylxanthate Ions .1. A Vibrational Spectroscopic Study of the Interactions between Sphalerite and Synthetic Zinc(Ii) and Cadmium(Ii) Sulfides, and Ethylxanthate Ions in Aqueous and Acetone Solutions

The crystal structures of zinc(II) and cadmium(II) sulphides are not affected by the stoichiometry of metal and sulphide ions at the precipitation of the two compounds. The composition and structure of the ultimate surface layers, and thereby the chemical properties of the particles, are on the other hand sensitive to the stoichiometry at the preparation. Chemisorbed ethylxanthate complexes are fo

Vitamin A helps gut T cells find their way in the dark.

Once activated, some T cells home to distinct sites in the body, such as the intestine and inflamed skin. Research in mice shows that dendritic cells in the gut produce a derivative of vitamin A, retinoic acid, that gives T cells directions.