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On the ripening of vesicle dispersions

We analyze the ripening process where, in a dispersion of vesicles, amphiphile monomers diffuse between vesicles of different sizes, leading to a change in the size distribution. Since, typically, vesicles are not under tension, the driving force for the process comes from the curvature energy. With the conventional expansion of the curvature energy density, g,, to harmonic order we find that the

Structure-function effects in primary immunodeficiencies

Several immunodeficiency-related genes have been identified and a large number of mutations in these genes. Currently, a genetic defect has been determined in more than 2000 patients. Only recently has it become possible to address structure-function effects of these mutations in the corresponding proteins. The consequences of mutations in structure are discussed for Btk in X-linked agammaglobulin

Interarticulator programming: effects of closure duration on lip and tongue coordination in Japanese.

This paper examines the coordination of lip and tongue movements in sequences of vowel-bilabial consonant-vowel where the duration of the oral closure for the consonant is varied for linguistic purposes. Native speakers of Japanese served as subjects. The linguistic material consisted of Japanese word pairs that only differed in the duration of the labial consonant, which was either long or short.

Accelerated Monte Carlo models to simulate fluorescence spectra from layered tissues

Two efficient Monte Carlo models are described, facilitating predictions of complete time-resolved fluorescence spectra from a light-scattering and light-absorbing medium. These are compared with a third, conventional fluorescence Monte Carlo model in terms of accuracy, signal-to-noise statistics, and simulation time. The improved computation efficiency is achieved by means of a convolution techni

Immunogenicity properties of authentic and heterologously synthesized structural protein VP2 of infectious pancreatic necrosis virus.

The sole coat protein VP2 of infectious pancreatic necrosis virus (IPNV) was isolated and purified from intact virions, propagated in CHSE-214 cells. Likewise was the full-length VP2 protein isolated and purified upon cloning and expression of the corresponding complete gene in E. coli. The two purified proteins of different synthetic origins carrying identical primary structures were utilized in

Onshore climate change during the late triassic marine inundation of the Central European Basin

Sedimentological, pedological and palynological evidence reveal radically increasing onshore humidity during the Rhaetian marine invasion of central Europe along the north-eastern margin of the Central European Basin (southern Sweden). Pre-Rhaetian aridity favoured the formation of Carnian redbeds with calcrete, which were succeeded by Norian hematite-cemented conglomerates, arkoses, arkosic wacke

Jurassic smectite and kaolinite trends of the East European Platform: implications for palaeobathymetry and palaeoclimate

Clay minerals cannot only give information on sedimentary depositional environment but also the climate regime under which sediment was weathered. The successions of non-marine to marine Middle and Late Jurassic strata of the East European Platform show upwards increasing contents of smectite and decreasing contents of kaolinite. There is also an increasing smectite vs. kaolinite ratio laterally,

RECENT ADVANCES AND TRENDS IN MEDICAL X-RAY AND MOLECULAR IMAGING

This paper is intended to give an overview of clinically used imaging methods with special reference to digital techniques and 3D techniques for X-ray and nuclear medicine/molecular imaging such as CT, SPECT and PET. The paper will focus on recent advances and trends.

Patterns of Prominence in L2 : Observations from Learners of Swedish with L1S of Diverse Prominence Properties

Swedish has – like other Germanic languages – flexible stress placement, which underlies morphological rules and is also based on the individual word’s origin. The achievement of the correct usage when learning Swedish is challenging. As second language learners of Swedish in the classrooms present speakers of a variety of first languages (L1s), the opportunity has been taken to have a closer look

Galectin binding proteins in serum and bronchoalveolar lavage -in healthy and pathological conditions

Galectins are carbohydrate binding proteins, implicated in conditions of both inflammation and cancer. Connections between chronic inflammation and cancer are proposed by the increased remodelling and proliferation that occurs, leading to enhanced survival and proliferation of malignant cells. Since galectins have been implicated in mechanisms of both chronic inflammation and cancer, we have inves

Time Scales of Conformational Gating in a Lipid-Binding Protein

Lipid-binding proteins Sequester amphiphilic molecules in a large internal : cavity occupied by similar to 30 water molecules, some of which are displaced by the ligand. The role; of these internal water molecules in lipid binding and release is not understood. We use magnetic relaxation dispersion (MRD) to directly monitor internal-water dynamics in apo and palmitate-bound rat intestinal fatty ac

Vowel-to-vowel coarticulation in Japanese: The effect of consonant duration (L)

This paper examines vowel-to-vowel lingual coarticulation in sequences of vowel-bilabial consonant-vowel, where the duration of the oral closure for the consonant is either long or short. Native speakers of Japanese served as subjects. The linguistic material consisted of Japanese word pairs that only differed in the duration of the labial consonant, which was either long or short. Recordings were

Does the Dynamic Stokes Shift Report on Slow Protein Hydration Dynamics?

The time-dependent fluorescence frequency shift of protein-attached probes has a much slower decay than that for the free probe. The decay times, ranging from 10 ps to several nanoseconds, have been attributed to hydration water motions several orders of magnitude slower than those in the hydration shell of small solutes. This interpretation deviates strongly from the prevailing picture of protein