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Asthma is a highly prevalent condition across Europe and numerous guidelines have been developed to optimise management. However, asthma can be neither cured nor prevented, treatment choices are limited and many patients have poorly controlled or uncontrolled asthma. The Brussels Declaration on Asthma, sponsored by The Asthma, Allergy and Inflammation Research Charity, was developed to call attent
A single intradermal injection of the mineral oil pristane in susceptible DA.1F rats induces erosive arthritis closely mimicking rheumatoid arthritis (RA). Pristane-induced arthritis (PIA) is driven by autoreactive T cells but no autoantigen has been identified to date. We therefore analyzed B and T cell responses to autoantigens potentially involved in the pathogenesis of RA, including IgG, citru
Weakly coupled relaxors based on compositions (1-x) BaTiO 3 -xBiMeO 3 , where Me is a metal ion, have attracted attention as potential candidates for high-temperature high-energy density capacitors. However, the necessary Bi content is typically high with x = 0.3-0.4. In order to reduce problems associated with compatibility for base metal electrodes and due to additional problems due to Bi vol
Introduction: For fast and effective antibiotic therapy of serious infections like sepsis, it is crucial with rapid information about antibiotic susceptibility, especially in a time when the number of infections caused by multi resistant bacteria has escalated in the world. Methods: Here, we have used a semi-quantitative MALDI-TOF-MS based method for antibiotic resistance detection, MBT-ASTRA™, wh
This thesis addresses how verbal comprehension is affected by seeing the speaker and in particular when the speaker is an animated virtual speaker. Two people visually co-present – one talking and the other listening, trying to comprehend what is said – is a central and critical scenario whether one is interested in human cognition, communication or learning. Papers I & II are focused on the e
The introduction of a mollecular method to identify the Entoviruses based on the amplification sequecing and phylogenetic analysis of protein VPI was described. It was proved that this method reduces significantly the time required for the identification of the isolated Entoviruses and that it is very useful in the characterization of isolates which are difficult to typify by the routine immunoloi
Does a teachable agent influence the uptake or neglect of ‘critical constructive feedback’ and learning within a digital environment? 285 middle-school students engaged with a history learning game in a 2x2 study design. One dimension was inclusion of a teachable agent. Orthogonal was whether critical constructive feedback was presented automatically or only when students chose. Analyses showed th
Context.-The diagnostic distinction of pulmonary neuroendocrine (NE) tumors from non-small cell lung carcinomas (NSCLCs) is clinically relevant for prognostication and treatment. Diagnosis is based on morphology and immunohistochemical staining. Objective.-To determine the diagnostic value of insulinoma-associated protein 1 (INSM1), in comparison with established NE markers, in pulmonary tumors. D
In 2010, Spence and Van Gelder presented a family of CNF formulas based on combinatorial block designs. They showed empirically that this construction yielded small instances that were orders of magnitude harder for state-of-the-art SAT solvers than other benchmarks of comparable size, but left open the problem of proving theoretical lower bounds. We establish that these formulas are exponentially
Stapylococcus aureus is a common infectious agent in e.g. sepsis, associated with both high mortality rates and severe long-term effects. The cytolytic protein α-hemolysin has repeatedly been shown to enhance the virulence of S. aureus. Combined with an unhindered spread of multi drug-resistant strains, this has triggered research into novel anti virulence (i.e. anti α-hemolysin) drugs. Their func
To date, few studies have investigated the simultaneous effects of macro-scale parameters (MSPs) such as land use, population density, geology, and erosion layers on micro-scale water quality variables (MSWQVs). This research focused on an evaluation of the relationship between MSPs and MSWQVs in the Siminehrood River Basin, Iran. In addition, we investigated the importance of water particle trave
The issue of Critical Raw Materials (CRMs) and potential interruptions to their supply andavailability due to concerns such as shortages, trade restrictions or geopolitical considerations are topicsthat are relatively unknown to the general public. Education and the dissemination of this informationamongst the general public has been promoted as a key factor in addressing this and enabling thetran
Popular Abstract in Swedish I sökandet efter den rådande fostrings- och disciplineringsdiskursen i svensk skola åren 1947-1956 har Michel Foucaults diskursanalys utgjort en central utgångspunkt i denna avhandling. Jag har inledningsvis redogjort för modernitetens genombrott i Sverige och kort belyst befolkning och utbildning vid mitten av 1900-talet. Skolan som disciplineringsinstitution har beskThe purpose of this monograph is to discern what constituted the dominant fostering and discipline discourse in Swedish compulsory schools during the period 1947-1956. For this purpose Michel Foucault's discourse analysis has played a central role in this thesis. As a starting point, an account of the emergence of modernity in Sweden is given, as well as a brief presentation of the Swedish populat
This study considers the spread, character and development of the Swedish Enlightenment from the early Age of Liberty to the late Karl lohan period. This is done in six case studies three of them biographical and three of them of a more general character partly concerned with the history of concepts; all six case studies touch on the writers' world in the period. Chapter 1, "Dawn", discusses, aft
In 2003 Lund University Commissioned Education was given the task, after publictender, to create and administrate a programme on “Child Rights, Classroom andSchool Management” following the provisions and principles contained in the UNConvention on the Rights of the Child (CRC), Sida’s development policy on Education and other internationally ratified instruments in the areas of child rights and e
Societal functions constitute of public and private organisations and companies that provide commodities and services that are vi-tal for the functioning of the modern society. The public are highly dependent on these vital societal services and commodities, such as power supply, health care and education. In this paper we present an application of a method for collecting and structuring data and
We have experimented with a bio-inspired selforganizingtexture and hardness perception system whichautomatically learns to associate the representations of the twosubmodalities with each other. To this end we have developeda microphone based texture sensor and a hardness sensor that measures the compression of the material at a constant pressure. The system is based on a novel variant of the Self-
