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OBJECTIVE: To explore physicians' thoughts and considerations of participation in medical decision making by hospitalised elderly patients.DESIGN: A qualitative study using focus group interviews with physicians interpreted with grounded theory and completed with a questionnaire.SETTING AND PARTICIPANTS: The setting was three different hospitals in two counties in Sweden. Five focus groups were co
Rare inherited bleeding disorders (IBD) are a common cause of bleeding tendency. To ensure a correct diagnosis, specialized laboratory analyses are necessary. This study reports the results of an upfront diagnostic strategy using targeted whole exome sequencing. In total, 156 patients with a significant bleeding assessment tool score participated in the study, of which a third had thrombocytopenia
Polycomb Repressor Complexes (PRCs) are important regulators of embryogenesis. In embryonic stem (ES) cells many genes that regulate subsequent stages in development are enriched at their promoters for PRC1, PRC2 and Ser 5-phosphorylated RNA Polymerase II (RNAP), and contain domains of 'bivalent' chromatin (enriched for H3K4me3; histone H3 di-or trimethylated at Lys 4 and H3K27me3; histone H3 trim
A search for heavy pseudoscalar (A) and scalar (H) Higgs bosons decaying into a top quark pair (tt) has been performed with 20.3 fb-1 of proton-proton collision data collected by the ATLAS experiment at the Large Hadron Collider at a center-of-mass energy s=8 TeV. Interference effects between the signal process and standard model tt production, which are expected to distort the signal shape from a
The respiratory gas exchange and ventilation during an incremental cycle exercise test were analysed in a group of 19 healthy, moderately fit men. Different computer algorithms were used to estimate the VO2 values where: (i) the rate of VCO2 increase just exceeds the rate of VO2 increase (DX, derivative crossing), (ii) VCO2/VO2 = 1·00 (PX, point of crossing) and (iii) ventilation (VE) increases di
Data are presented on the number of fibers and the proportion of different fiber types within fascicles of whole vastus lateralis muscles from 5 male children, 5 to 15 years of age, and compared with results from 25 male adults, middle aged and old individuals. The results verify a difference in the proportion of fibers with different properties within a fascicle. The proportion of type 2 (fast tw
During the 1990s three new techniques to reduce spasticity and dystonia in children with cerebral palsy (CP) were introduced in southern Sweden: selective dorsal rhizotomy, continuous intrathecal baclofen infusion and botulinum toxin treatment. In 1994 a CID register and a health care programme, aimed to prevent hip dislocation and severe contractures, were initiated in the area. The total populat
A sequence in the Upper Silurian Oved-Ramsasa Group in Scania, Sweden has been investigated sedimentologically and geochemically. This sequence represents a regressive marine succession. The sedimentary structures and the rapid vertical changes in lithologies and the lateral variability of beds indicate a tide-dominated sedimentation in a shallow epeiric sea, where even small oscillations in sea w
HAMLET (human alpha-lactalbumin made lethal to tumor cells) is a tumoricidal complex consisting of partially unfolded protein and fatty acid, and was first identified in casein fractions of human breast milk. The complex can be produced from its pure components through a modified chromatographic procedure where pre-applied oleic acid binds with partially-unfolded alpha-lactalbumin on the stationar
The genetic basis of complete C4 deficiency in a patient with SLE was investigated. Previous studies have demonstrated that this patient has two different major histocompatibility complex (MHC) haplotypes that each contain a major deletion and a non-expressed C4 gene. In the present study, non-expression of the C4 genes was explained by the finding of two distinct C4 gene mutations. A previously d
The ICAO approach to risk management is essentially a technical model based on an engineering process viewpoint and is more applicable in concept to stable systems, such as chemical and nuclear industries. If airlines are to manage risk in a proactive manner they need to apply risk detection tools that provide real time and continuous systems oversight. This paper describes briefly the systems ap
Our hypothesis was that carbohydrate, fat, and protein contents of meals affect satiety, glucose homeostasis, and hormone secretion. The objectives of this crossover trial were to examine satiety, glycemic-insulinemic response, and plasma peptide levels in response to 2 different recommended diabetes diets with equivalent energy content. One traditional reference breakfast and one test breakfast,
The museum world is in a time of great change, many of the changes focus on the accessibility of museums. In Sweden these changes are becoming more apparent as the new museum law that has been passed advocates for equal museum experience for all visitors whether they have any for of impairment or not. To encourage this change a few older law and regulations that Swedish museums are also subject to
När Lissabonfördraget trädde i kraft den 1 december 2009 medförde det viktiga förändringar inom EU:s utrikespolitik. Målet var att öka EU:s samstämmighet i dess externa relationer i syfte att stärka EU:s roll som global aktör. Det nya fördraget inrättade en hög representant för den gemensamma utrikes-och säkerhetspolitiken (HR) samt en assisterande utrikestjänst (EEAS). De nya funktionerna är histThe entry into force of the Lisbon Treaty in December 2009 brought several important changes in the field of EU Foreign Policy. The goal was to enhance coherence in EU external relations to strengthen the role of the EU as a global actor. The creations of the High Representative (HR) of the Union on Foreign Affairs and Security Policy and the assisting European External Action Service (EEAS) are t
Spatial and temporal variations in malaria transmission are naturally associated with prevailing climatic and environmental factors, for example rainfall, humidity, temperature and human activities. These factors influence malaria transmission mainly in non-deterministic ways, making them less appropriate for accurate geographical mapping of malaria risk. One distinctive phenomenon, ‘photosyntheti
