No title
This master’s thesis focused on the crystallisation of E. coli ribonucleotide reductase repressor (NrdR) in the scope of fragment-based drug design. Antibiotic resistance is a growing problem and NrdR is thought to be a potential drug target for a new group of antibiotics. NrdR proteins are only found in bacteria and regulate the transcription of ribonucleotide reductase genes by binding to two Nr
