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Cross-Germanic Promotion to Subject in Ditransitive Passives – a Feature-Driven Account

Languages differ with respect to which element they select as the subject in passive of ditransitive verbs: either the active indirect object (the goal argument) or the active direct object (the theme argument). In standard American English, e.g., only the goal argument may be promoted, as shown by the difference between (1b) and (1c). (1) a. John gave Mary a red bike yesterday. b. Mary was give

DNA-dependent protein kinase in human cells

DNA-dependent protein kinase (DNA-PK) is a holoenzyme consisting of a regulatory subunit, the heterodimeric Ku70/86, and a catalytic subunit known as DNA-dependent protein kinase catalytic subunit (DNA-PKcs). DNA-PK takes part in a number of cellular functions including growth control, immunoglobulin gene rearrangement and DNA repair. The Ku86 subunit of DNA-PK has been reported to exist in human

Regulation of normal and cancer cells as a base for cell cycle-targeted therapy

Popular Abstract in Swedish De flesta cancerpatienter dör på grund av spridning av tumörceller till olika organ. Invasiv och metastaserande cancer svarar ofta inte på behandling och blir då i många fall dödlig. Leukemi är en elakartad sjukdom av blodceller, som påverkar blod-producerande organ. Den höga förekomsten av leukemi förekommer i äldre befolkningen och hos barn. Leukemi återfall och resiThe majority of current treatments used for treatment of prostate cancer (PCa) and leukemia are often limited to a narrow subsets of treated patients. As such, there still remains a significant scope for gaining deeper understanding of molecular mechanisms underlying cancer metastasis for improvement of targeted treatment. Elevated expression of a cell cycle regulator cyclin A1 initiated leukemia

Importance of vegetation dynamics for future terrestrial carbon cycling

Terrestrial ecosystems currently sequester about one third of anthropogenic CO 2 emissions each year, an important ecosystem service that dampens climate change. The future fate of this net uptake of CO 2 by land based ecosystems is highly uncertain. Most ecosystem models used to predict the future terrestrial carbon cycle share a common architecture, whereby carbon that enters the system as net p

The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes.

Aims: We tested whether autoantibodies to all three ZnT8RWQ variants, GAD65, insulinoma-associated protein 2 (IA-2), insulin and autoantibodies to islet cell cytoplasm (ICA) in combination with human leukocyte antigen (HLA) would improve the diagnostic sensitivity of childhood type 1 diabetes by detecting the children who otherwise would have been autoantibody-negative. Methods: A total of 686 pat

Rethinking Son Preference : Gender, Population Dynamics and Social Change in the People’s Republic of China

This dissertation explores how son preference is constructed and renegotiated in light of social change in the People’s Republic of China (PRC). Based on secondary sources and interviews with women and men in rural Anhui Province as well as key informants, it addresses son preference from conceptual, methodological, empirical and ideological perspectives. The analysis centres around son preference

Complement in Disease - Extracellular Proteins as Complement Regulators

Complement activation occurs during inflammatory joint diseases such as rheumatoid arthritis (RA) and is thought to contribute to the chronic inflammation observed within the joints. Previous studies have shown that certain cartilage components of the small leucine-rich repeat protein (SLRP)-family regulate complement activity, thereby possibly contributing to disease progression. The aim of this

Adult Neural Stem Cells-Influence of Stroke, Inflammation and Aging

Neural stem cells (NSCs) in the embryo generate neurons, astrocytes and oligodendrocytes, the principal cells of the central nervous system (CNS), which contribute to the full diversity of the brain. Some NSCs persist in the adult brain and ensures neurogenesis throughout adult life in the subventricular zone (SVZ) and the subgranular zone (SGZ). NSCs in the SGZ generates neurons in the granule ce

Group supervision in nursing care. A longitudinal study of psychiatric nurses´ experiences and conceptions

Popular Abstract in Swedish Inom hälso- och sjukvården betonas att vården ska ges utifrån ett patientorienterat sätt. Om sjuksköterskor skall kunna ge patienten god omvårdnad, måste de själva ha en god arbetssituation. Det blir allt vanligare att sjuksköterskor i arbetet utsätts för en mängd negativa psykiska påfrestningar, såsom hot och våld, som kan leda till stress. Stress kan också relateras tThe purpose of group supervision in nursing care is to understand nurses’ experiences from real care settings and to structure these in a professional and personal context. An interventional and longitudinal method of research was chosen in this study of group supervision in nursing care. The overall aim of the present study was to examine and investigate how psychiatric nurses’ professional compe

Att gotta sig i det gamla : en undersökning av autenticitet vid två svenska museer

The concept of authenticity is hard to define and may vary in time, place, and between different cultures and societies. We have aimed to explore the emotional experience of authenticity, the fascination for the real things from the past. In this thesis we have approached the subject in a museum context, specifically in historical exhibitions. The emphasis is on how museum staff argues the use of

Att anpassa affärsmodellen

ABSTRACT Already in 1960, the Harvard professor Theodore Levitt concluded that without the capabilities to adapt, companies risk missing imminent trends and changes in the market and could suddenly be outrun by competitors. The subject of business model adaption has since been heavily discussed and is, if possible, of even greater importance today. With this thesis, the authors aspires to cast lig

Som en jojo i konkurs - Kapitalförstörelse i likvidations- och konkursinstitutet genom jojo-effekten

Uppsatsen behandlar fenomenet som uppstår när tillgångarna i ett bolag som ska avvecklas inte är tillräckligt stora för att täcka likvidationskostnaderna men samtidigt för stora för att en konkurs ska kunna avslutas utan överskott, då kommer nämligen bolaget att gå i konkurs om och om igen tills tillgångarna tagit slut, en s k jojo-konkurs. Syftet med uppsatsen är att utreda förhållandet mellan liThe essay deals with the occurrence that when a company is to be terminated and the assets do not cover the liquidation costs and at the same time are too big for a bankruptcy to be completed without excess, then the company will go bankrupt again and again until the assets are exhausted. This is what I call a yo-yo bankruptcy. The purpose of this essay is to investigate the relationship between t

Synnerligen ömmande omständigheter inom migrationsrätten

Den här uppsatsen har som syfte att klarlägga vad bestämmelsen om synnerligen ömmande omständigheter inom den svenska migrationsrätten innebär och hur tillämpningen av den ser ut i praktiken samt hur denna praktiska tillämpning påverkas av förarbeten och praxis. Syftet har även varit att försöka klargöra om det finns en skillnad i tillämpningen mellan barn och vuxna. Bestämmelsen om synnerligen ömThis dissertation aims to clarify the regulation concerning particularly distressing circumstances in Swedish migration law and how the enforcement of this regulation works in practice and in which way propositions and superior court decisions has an effect on the practical application. The purpose has also been to clarify what distinction there are between children and adults within the Swedish m

Framtagning av BIM-objekt för byggsystemleverantörer, undertaksystem från Ecophon

Background BIM, Building Information Modelling, is a relatively new approach to work with building design and information management within the building industry. As higher demands are placed on product information and information management, manufacturers of building materials have to meet the need for BIM objects and 3D modeling. Ecophon is a supplier of sound absorbing ceilings and wall absorbe

Simulating current regional pattern and composition of Chilean native forests using a dynamic ecosystem model

Popular Summary Native forests are one of the most important natural resources in Chile and cover 13.6 million ha in Chile (18% of the country area). These forests provide a wide range of ecosystem services but have been negatively affected by drastic land-use changes. Taking into account that future climate and land-use changes will affect these ecosystems, it is important to have efficient tools

The Packaging's Role in Prevention of Product Waste - The supply Chain of Bread

Purpose - Food lost or wasted constitutes a substantial environmental, economic and social problem; today roughly one-third of edible parts of food that is produced for human consumption globally gets lost or wasted. Thus, a reduction of waste would contribute to a sustainable use of resources. It has been highlighted that packaging development has the potential to play an important role in this p

Litostratigrafiska studier av en platåformad sand- och grusavlagring i Skuremåla, Blekinge

I Skuremåla, Blekinge har litostratigrafiska studier utförts av en platåformad grus- och sandavlagring. Skuremåla-avlagringen har tidigare beskrivits som ett delta med en överyta på 55 m ö h. Syftet med arbetet är att tolka vad för sorts ”delta” Skuremåla-avlagringen utgör samt depositionsmiljön för sedimenten i fråga. I denna studie har området undersökts genom jordartskartering samt genom skruvbA lithostragraphic study has been performed of a plateau-shaped sand and gravel deposit at Skuremåla in Blekinge, SE Sweden. The Skuremåla deposit has earlier been described as a delta with an upper surface 55 m a.s.l. The purpose of this study is to re-evaluate this interpretation, i.e. is the Skuremåla deposits a delta or possibly another type of formation. Furthermore, the investigation aims at

Försäkringsbolagets lojalitetsplikt

I denna framställning behandlas fyra huvudsakliga frågeställningar beträffande den avtalsrättsliga lojalitetsplikten som försäkringsbolag har att beakta i företagsförsäkringsavtal. Beträffande den fösta frågeställningen, vad lojalitetsplikten i dessa avtal grundas på, kan följande konstateras. Plikten innebär att parterna med omsorg har att iaktta och tillvarata motpartens intressen i avtalsförhThis presentation deals with four main issues concerning the contractual duty of loyalty which insurance companies have to consider in business insurance agreements. Regarding the first question at issue - what the duty of loyalty in these agreements is based on - the following can be stated. The duty implies that the parties with care observe and exploit the counterparty’s interests in the cont

Familjeägda aktiebolag - skydd av ägarpositioner

Uppsatsen behandlar frågan om skydd av ägarpositioner i anslutning till familjeägda aktiebolag. Anledningen till uppsatsens tema är att familjeägda aktiebolag har en särprägel som avviker från det efter ABL konstruerade aktiebolaget. Detta uttrycks, till exempel genom att ägarna i det familjeägda bolaget vanligtvis har ett särskilt behov av att skydda ägarkretsens sammansättning under en längre peThis paper is on protection of ownership positions in relation to family-owned businesses. The reason for the papers theme is that family-owned businesses have a distinctive character that deviates from the construction in the Companies Act. For example, owners of a family-owned business usually have a particular need to protect the ownership structure for a longer period of time. To put the famil

Fri kontra reglerad hyressättning – En studie av Stockholms hyresbostadsmarknad

Several Swedish municipalities, in particular Stockholm inner city, suffer from excessive housing shortage – demand exceeds supply by far. The result of this is for example a market with a long housing queue, illegal trade with lease agreements and rental houses being transformed into building societies. These problems are due to the fact that the rental housing market in Sweden is controlled and