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Testing Highly Complex System of Systems: An Industrial Case Study

Context: Systems of systems (SoS) are highly complex and are integrated on multiple levels (unit, component, system, system of systems). Many of the characteristics of SoS (such as operational and managerial independence, integration of system into system of systems, SoS comprised of complex systems) make their development and testing challenging. Contribution: This paper provides an understanding

Nutrient balance and salinity stress in arbuscular mycorrhizal fungi

Earth’s primary production depends to a considerable extent on the mycorrhizal symbiosis, since mycorrhizal fungi supply their host plant with important mineral nutrients. I examined the influence of different nutrient regimes on the fungal partner in the arbuscular mycorrhizal symbiosis. I especially focused on salinity problems, as they occur in southern Tunisia, where I performed several field

Processes of long-term coastal evolution and their mathematical modelling : Application to the Mozambican coast

Different processes in response to the action of natural driven forces and the human interference on coastal systems act together, contributing to shape the coast. Coastal evolution models have been developed as useful tools to better understand the contribution of different processes on observed coastal changes, and also to anticipate future evolution in response to different actions and interven

'Struggling to be a defender of health' -a qualitative study on the pharmacists' perceptions of their role in antibiotic consumption and antibiotic resistance in Romania

BACKGROUND: Antibiotic resistance is a serious global public health problem directly correlated to high antibiotic consumption. Romania is one of the European countries with the highest rates of antibiotic consumption, non-prescription antibiotics use and resistance of several pathogens to antibiotics. Pharmacists are an important stakeholder in respect to antibiotic management and context specifi

The color of child survival in Colombia, 1955-2005

Objective(s): Colombia has the third largest black population in the Americas after Brazil and the USA. In 2005 mortality rate under 5 in Colombia was 21.5 per 1000, with a reduction of 82 per cent between 2005 and 1960. That rate is not in line with rates for Cuba (6.8), Chile (9.1) or Costa Rica (10.4). Here we aim to provide evidence that a further reduction of child mortality relates to the un

From technological to symbolic innovation? Open source, Maker Movement and global demand for 3D printers

Abstract: The recent turbulent evolution of the 3D printing industry is strictly related with two important phenomena: the widespread adoption of Open Source (OS) business models by new companies on the one hand, and the increasing importance of communities of users, such as the so-called Maker Movement, on the other. This study is the first to analyze the factors that drive the adoption of differ

Evolutionary History of the Marchantia polymorpha Complex

The potential role of introgression in evolution has gained increased interest in recent years. Although some fascinating examples have been reported, more information is needed to generalize the importance of hybridization and introgression for adaptive divergence. As limited data exist on haploid dominant species, we analyzed genomes of three subspecies of the liverwort Marchantia polymorpha. We

The risk of carbon leakage in global climate agreements

Although climate change and international trade are interdependent, policy-makers often address the two topics separately. This may inhibit progress at the intersection of climate change and trade and could present a serious constraint for global climate action. One key risk is carbon leakage through emission outsourcing, i.e. reductions in emissions in countries with rigorous climate policies bei

Politikens drivfjäder : Frihetstidens partiberättelser och den moralpolitiska logiken

Denna avhandling studerar den moraliska konfliktlinje som genomsyrade den frihetstida politiken åren kring 1740 och som strukturerade politiken enligt en särskilt moralpolitisk logik. Logiken hade sin grund i dels samhällsordningens absoluta och normativt oföränderliga karaktär, dels ett antal djupa förmoderna erfarenheter av och förväntningar på människan som oförmögen att hantera sin fördärvade This thesis examines the moral conflict permeating the politics of Sweden’s Age of Liberty around 1740 – a conflict that also structured the politics of the time in relation to a particular political logic based on moral. This logic was based on the absolute and normatively immutable nature of the social order, but also on a number of deep pre-modern experiences and expectations of man as unable t

Sustainable and Safe Use of Non-conventional Waters -Reclaimed Water and Desalinated Water

Popular Abstract in Swedish Vatten är inte bara en oumbärlig resurs varav allt liv är beroende. Det är också en grundläggande ekonomisk resurs för samhällsutvecklingen. Av allt vatten på jorden är bara 0,34% tillgängligt för människan. Övriga vattenresurser föreligger som saltvatten, is eller djupt liggande grundvatten. Vattenkrisen på jorden är stor och över 780 miljoner människor saknar rimlig tFresh water scarcity, pollution and an uneven distribution have caused an increasingly serious global water crisis. One of the most widely adopted response strategies is the exploitation and use of non-conventional water sources. Water reuse and desalination were in focus in the study which was aimed to develop the strategies to promote the sustainable and safe use of reclaimed water and desalinat

Notable plesiomorphies and notable specializations : Head structure of the primitive "tongue moth" Acanthopteroctetes unifascia (lepidoptera: Acanthopteroctetidae)

The Acanthopteroctetidae are one of the first-originated family-group lineages within "tongue moths" (Lepidoptera-Glossata). The purpose of this study is to provide a comprehensive account (based on whole mount preparations, serial sections, and Scanning electron microscopy) of the cephalic structure of an adult exemplar of the family, to supplement the sparse available information. Notable plesio

Low-level exposure to lead, blood pressure, and hypertension in a population-based cohort

Background: Environmental lead exposure is a possible causative factor for increased blood pressure and hypertension, but large studies at low-level exposure are scarce, and results inconsistent. Objective: We aimed to examine the effects of environmental exposure to lead in a large population-based sample. Methods: We assessed associations between blood lead and systolic/diastolic blood pressure

Supplying rural Kazakhstan with safe water and sanitation

Access to safe drinking water and sanitation is essential for both individual and population health as well as for quality of life and dignity. The UN Sustainable Development Goals (SDGs) require nations to ensure adequate water supply and sanitation for all. For Kazakhstan, this means that rural areas will need a much stronger attention as they have been rather neglected in efforts to comply with

Ideology, politics and war violence as sources of forced migrations

The symbolic order of discourse of ideology actually enables the existence and reproduction of violence. Mass crimes on civilians may become normalized and widely accepted if perpetrators of violence who exert violence and those who implicitly and explicitly support it believe that exertion of violence on others is justified by belief in some symbolic higher order. Many current examples of justifi

Polymorphisms in ATP-binding cassette transporters associated with maternal methylmercury disposition and infant neurodevelopment in mother-infant pairs in the Seychelles Child Development Study

Background: ATP-binding cassette (ABC) transporters have been associated with methylmercury (MeHg) toxicity in experimental animal models. Aims: To evaluate the association of single nucleotide polymorphisms (SNPs) in maternal ABC transporter genes with 1) maternal hair MeHg concentrations during pregnancy and 2) child neurodevelopmental outcomes. Materials and methods: Nutrition Cohort 2 (NC2) is

Short-term fluctuations in air pollution and asthma in Scania, Sweden. Is the association modified by long-term concentrations?

Background and aims: Asthma is one of the most common respiratory diseases in the world. Research has shown that temporal increases in air pollution concentrations can aggravate asthma symptoms. The aim of this study was to assess whether individuals living in areas with higher air pollution concentrations responded differently to short-term temporal exposure to air pollution than those living in

Embedding fragment ab initio model potentials in CASSCF/CASPT2 calculations of doped solids: Implementation and applications

In this article, we present a fragment model potential approach for the description of the crystalline environment as an extension of the use of embedding ab initio model potentials (AIMPs). The biggest limitation of the embedding AIMP method is the spherical nature of its model potentials. This poses problems as soon as the method is applied to crystals containing strongly covalently bonded struc

Should boxing be banned?

Should boxing be banned? Do the ever-so-obvious risks outweigh everyone's freedom to choose whether to expose oneself to these risks by taking up the sport? On an official level, the RCN in the UK has taken its stand--it does not! So has also the British Medical Association (BMA)--it does! With few exceptions, the responding nurses from Europe, America, and Australia in this month's column seem to

Ghrelin affects gastrectomy-induced decrease in UCP1 and beta(3)-AR mRNA expression in mice.

this study we investigated the effects of gastrectomy (Gx) and of the gastric hormone, ghrelin, on the expression of proteins in brown adipose tissue (BAT) that are thought to be involved in thermogenesis. Heat production in BAT is known to depend upon activation and increased expression of β3-adrenergic receptors (β3-AR) and the consequent up-regulation of uncoupling protein 1 (UCP1). Mice were s