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Introduction Fever is an integral part of the inflammatory response and has therefore likely a physiological role in fighting infections. Nevertheless, whether fever in itself is beneficial or harmful in adults is unknown. This protocol for a systematic review aims at identifying the beneficial and harmful effects of fever control interventions in adults. Methods and analysis This protocol for a s

Transfusion-related acute lung injury (TRALI) is a life-threatening complication of acute respiratory distress occurring within 6 hours of blood transfusion. TRALI is one of the leading causes of transfusion-related fatalities and specific therapies are unavailable. Neutrophils are recognized as the major pathogenic cells, whereas T regulatory cells and dendritic cells appear to be important for p

OBJECTIVES: Cancer survival rates vary widely between European countries, with differences in timeliness of diagnosis thought to be one key reason. There is little evidence on the way in which different healthcare systems influence primary care practitioners' (PCPs) referral decisions in patients who could have cancer.This study aimed to explore PCPs' diagnostic actions (whether or not they perfor

This paper introduces a PhD project, exploring the process of transformation and appropriation of public spaces by immigrants, and how it results in new functions in post-industrial, transnational Malmö, Sweden. Such spaces have attained significant importance against the backdrop of increasing ethnic and economic segregation. The project is methodologically based on ethnographic research, documen

BACKGROUND AND OBJECTIVES: Degarelix is a gonadotropin-releasing hormone antagonist registered for the treatment of advanced hormone-dependent prostate cancer. Treatment causing androgen deprivation is associated with QT prolongation and this study investigated whether degarelix at supratherapeutic concentrations has an intrinsic effect per se on cardiac repolarisation and the QT interval.METHODS:

Cystic fibrosis (CF) is an inflammatory lung disease. Platelets have an emerging role in inflammation, however previous studies of platelet activation in CF have generated conflicting results. In this study, we determined platelet function in CF patients and correlated platelet activation to establish clinical and laboratory parameters. Twenty-two patients, aged 20.7 to 54.4 (mean 34.0, SD 9.45) y

Background and objectives: The Mi(a+) GP(B-A-B) hybrid phenotypes occur with a prevalence of 2%–23% across Southeast Asia. While the s antigen is alleged to be altered, no evidence for specific variants is known. Screening using a monoclonal IgM anti-s mistyped six S‒s+ RBC units as S‒s‒. Further, alloanti-s was identified in an S+s+ patient. Our objective was to investigate the s antigen further.

Zn 5Sb 4ln 2-δ (δ = 0.15(3)) was synthesized in the form of millimeter-sized crystals from reaction mixtures containing excess zinc. The ternary intermetallie compound is temperature polymorphic, and at room temperature it crystallizes with a new structure type in the orthorhombic space group Pbcn, where a = 7.1619(2), b= 17.1562(4), c=8.6887(4) Å, V = 1067.6(1) Å 3, and Z = 4. The structure featu

Background: There is a strong and consistent association between IgE sensitization and allergy, wheeze, eczema and food hypersensitivity. These conditions are also found in non-sensitized humans, and sensitization is found among individuals without allergy-related diseases. The aim of this study was to analyse the sensitization profile in a representative sample of the population, and to relate pa

Three injection strategies are compared in a light-duty (LD) diesel engine at a medium load point. One strategy, representative of a Euro 6 LD injection strategy, has a double-pilot/main/single-post sequence. There is a modest temporal spacing after the first pilot and second pilot. Additional strategies add a third pilot and greatly reduce the spacing after the pilots. These pilots are referred t

In year 2017 the WWN+ project "Silent Timber Build" is finishing. The project focused on studying timber structures with regard to their sound insulation characteristics, both airborne sound insulation and impact sound insulation. The aim is to develop calculation models (and / or to provide input to standardized models) for various timber structures available in Europe but also to facilitate futu

The impact of sample crushing on the detected porosity of hardened cement pastes by low temperature calorimetry (LTC) was studied using powder and cylinder samples. Two types of cements, CEM I and CEM III were used to prepare the pastes. A model porous material, MCM-41, was also used in order to investigate some aspects of the measurement and the evaluation approach. The powder and cylinder sample

Background: Despite virtually identical DNA sequences between the sexes, sexual dimorphism is a widespread phenomenon in nature. To a large extent the systematic differences between the sexes must therefore arise from processes involving gene regulation. In accordance, sexual dimorphism in gene expression is common and extensive. Genes with sexually dimorphic regulation are known to evolve rapidly

Objectives - In patients with large middle cerebral artery (MCA) infarcts, maximum brain swelling leading to cerebral herniation and death usually occurs 25 days after onset of stroke. The study aimed at exploring the pattern of compounds related to cerebral energy metabolism in infarcted brain tissue. Methods - Forty-four patients with malignant MCA infarcts were included after decision to perfor

The influence of adding poly(acrylic acids) of two different chain lengths (PAA(25) and PAA(6000)) on the phase behaviour of the amphiphilic triblock copolymer Pluronic (R) P104 (P104 = (EO)(27)(PO)(61)(EO)(27), where EO = ethylene oxide, PO = propylene oxide) in H2O was investigated. The resulting phase equilibria and structures were investigated by visual inspection, using crossed polarizers, an

We review approaches to predicting carbon and nitrogen allocation in forest models in terms of their underlying assumptions and their resulting strengths and limitations. Empirical and allometric methods are easily developed and computationally efficient, but lack the power of evolution-based approaches to explain and predict multifaceted effects of environmental variability and climate change. In

Background: SoPIP2;1 constitutes one of the major integral proteins in spinach leaf plasma membranes and belongs to the aquaporin family. SoPIP2;1 is a highly permeable and selective water channel that has been successfully overexpressed and purified with high yields. In order to optimize reconstitution of the purified protein into biomimetic systems, we have here for the first time characterized

Popular Abstract in Swedish Ljus växelverkar med materia på ett mycket specifikt sätt och är anledningen till att saker har färger, himlen är blå, vår spegelbild reflekteras i en spegel och att solljus kan delas upp i en regnbåge genom vattendroppar. Läran om hur ljus växelverkar med material - spektroskopi - används inom astronomi, kemi, fysik och medicin. Absorptionsspektroskopi studerar just huAbsorption spectroscopy constitutes a chemical analysis tool which can be applied to various samples and application fields. This thesis focuses on gas absorption spectroscopy with the means of diode lasers - tunable diode laser absorption spectroscopy, TDLAS. In particular, the absorption of gases inside porous scattering solids and liquids, referred to as GASMAS - gas in scattering media absorpt