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Harnessing local knowledge for scientific knowledge production : challenges and pitfalls within evidence-based sustainability studies

The calls for evidence-based public policy making have increased dramatically in the last decades, and so has the interest in evidence-based sustainability studies. But questions remain about what “evidence” actually means in different contexts and if the concept travels well between different domains of application. Some of the most relevant questions asked by sustainability studies are not, and

ICU-nurses' perceptions of responsibilities and organisation in relation to organ donation- a phenomenographic study.

ObjectivesAccording to the Istanbul declaration, health services should create better routines for identifying potential donors. A previous study involving 702 intensive and critical care (ICU) nurses revealed that only 48% trusted clinical diagnosis of brain death without a confirmatory cerebral angiography. The aim was to study ICU nurses’ perceptions of their experiences of professional respons

TFAP2B-Dietary protein and glycemic index interactions and weight maintenance after weight loss in the diogenes trial

Background:TFAP2B rs987237 is associated with obesity and has shown interaction with the dietary fat-to-carbohydrate ratio, which has an effect on weight loss. We investigated interactions between rs987237 and protein-to-carbohydrate ratio or glycemic index (GI) in relation to weight maintenance after weight loss. Methods: This study included 742 obese individuals from 8 European countries who par

Care and consequences of traumatic brain injury in Neolithic Sweden : A case study of ante mortem skull trauma and brain injury addressed through the bioarchaeology of care

A number of papers have provided insight into frequencies of violence-related trauma, especially skull trauma, in Northern European skeletal assemblages dating to the Neolithic and Bronze Age. Although the cases are often well described, they lack further discussion about the consequences of skull trauma for the injured individual and the implications for the surrounding society, especially consid

Light-dependent magnetoreception in zebra finches : - from behaviour to receptor

Fåglarnas förmåga att flyga över extremt långa sträckor utan att hamna vilse harförvånat människor i århundraden. Det är känt att djur kan använda solens ellerstjärnornas läge, landmärken och jordens magnetfält som informationskälla förorientering, det vill säga de kan använda källan för att få kompassinformation.Eftersom magnetfältet är närvarande överallt på planeten kan magnetiskkompassinformatIt is well known that animals can use a wide variety of information sources to help them orient and navigate asthey move over short or long distances. Birds can rely on information from the sun, the skylight polarizationpattern, the stars, landmarks and the Earth’s magnetic field for orientation and navigation. However, despite thebehavioural evidence supporting the use of the magnetic field as an

Measurement of the top-quark mass in tt¯ + 1-jet events collected with the ATLAS detector in pp collisions at √s = 8 TeV

A determination of the top-quark mass is presented using 20.2 fb−1 of 8 TeV proton-proton collision data produced by the Large Hadron Collider and collected by the ATLAS experiment. The normalised differential cross section of top-quark pair production in association with an energetic jet is measured in the lepton+jets final state and unfolded to parton and particle levels. The unfolded distributi

Process designs for novel pervaporation-based hybrid-processes to recover organic compounds from waste water

IntroductionAn overview of the different hybrid-processes combining pervaporation with a conventional separation as a tool to recover organic compounds from waste water will be given. Analysing potential applications shows that pervaporation alone will rarely be economical due to the purity required nowadays in waste water treatment. The limitation on flux owing to the activity being the driving f

Robot-assisted approach to cervical cancer (RACC) : An international multi-center, open-label randomized controlled trial

Background Radical hysterectomy with pelvic lymphadenectomy represents the standard treatment for early-stage cervical cancer. Results from a recent randomized controlled trial demonstrate that minimally invasive surgery is inferior to laparotomy with regards to disease-free and overall survival. Primary Objective To investigate the oncologic safety of robot-assisted surgery for early-stage cervic

Spatial analysis of HIV-TB co-clustering in Uganda

BACKGROUND: Tuberculosis (TB) is the leading cause of death for individuals infected with Human immunodeficiency virus (HIV). Conversely, HIV is the most important risk factor in the progression of TB from the latent to the active status. In order to manage this double epidemic situation, an integrated approach that includes HIV management in TB patients was proposed by the World Health Organizati

Crystal chemistry and defect structure of ekmanite : New data from transmission electron microscopy and Mossbauer spectroscopy

Ekmanite is a member of the 2:1 type modulated layer silicates such as ganophyllite and bannisterite. Its chemical composition can be represented by K(M20)[Si32O76](OH)16 (M = Fe2+, Mg2+, Mn2+) where three of eight Si-tetrahedra are inverted across the interlayer sharing an apical oxygen with similarly inverted tetrahedra from the adjacent layers. The arrangement of the regular, D, and inverted, R

Radiomics-Derived Brain Age Predicts Functional Outcome after Acute Ischemic Stroke

Background and ObjectivesWhile chronological age is one of the most influential determinants of poststroke outcomes, little is known of the impact of neuroimaging-derived biological "brain age."We hypothesized that radiomics analyses of T2-FLAIR images texture would provide brain age estimates and that advanced brain age of patients with stroke will be associated with cardiovascular risk factors a

Cloacal microbiota are biogeographically structured in larks from desert, tropical and temperate areas

BACKGROUND: In contrast with macroorganisms, that show well-documented biogeographical patterns in distribution associated with local adaptation of physiology, behavior and life history, strong biogeographical patterns have not been found for microorganisms, raising questions about what determines their biogeography. Thus far, large-scale biogeographical studies have focused on free-living microbe

Teaching as evolutionary precursor to language

The central thesis of this article is that the evolution of teaching is one of the main factors that lead to increasingly complex communicative systems in the hominin species. Following earlier analyses of the evolution of teaching, the following steps are identified: (i) evaluative feedback, (ii) drawing attention, (iii) demonstration and pantomime, (iv) communicating concepts, (v) explaining rel

Circulating vitamin D and breast cancer risk: an international pooling project of 17 cohorts

Laboratory and animal research support a protective role for vitamin D in breast carcinogenesis, but epidemiologic studies have been inconclusive. To examine comprehensively the relationship of circulating 25-hydroxyvitamin D [25(OH)D] to subsequent breast cancer incidence, we harmonized and pooled participant-level data from 10 U.S. and 7 European prospective cohorts. Included were 10,484 invasiv

Computational Studies of Metalloenzymes

Enzymes are involved in most reactions in nature. They are important both for the understanding of biological life and for reactions of industrial interest, e.g. in the production of artificial fertilizers, the production of biomass or biofuels. Enzymes with one or several metal ions are called metalloenzymes. In this thesis we study three different metalloenzymes, nitrogenase, lytic polysaccharid

Effectiveness of women-led community interventions in improving tuberculosis preventive treatment in children : results from a comparative, before-after study in Ethiopia

OBJECTIVES: Our objective was to evaluate the impact of a service delivery model led by membership-based associations called Iddirs formed by women on tuberculosis preventive treatment (TPT) initiation and completion rates among children.DESIGN: Comparative, before-and-after study design.SETTING: Three intervention and two control districts in Ethiopia.PARTICIPANTS: Children who had a history of c

Bypassing the animal : Plant-based meat and the communicative constitution of a moral market

The food industry occupies a large portion of the plate in the study of moral markets. Moral markets for food include fair trade goods, organic products, family farmers initiatives, as well as plant-based meat alternatives, the focus of this paper. Driven by a growing concern for animal welfare, sustainability and the responsible use of resources, various companies launched products that successfu

Use of data mining and artificial intelligence to derive public health evidence from large datasets

This thesis explores the use of data mining and AI-tailored frameworks for extracting public health evidence from large health datasets. The research presented in this thesis demonstrates the potential of these tools for automating and simplifying the data mining process, and for providing valuable insights into various public health issues.In Paper I, we used data mining and natural language proc