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Recombinant activated coagulation factor VII (rFVIIa) was developed for the treatment of patients with hemophilia who have developed inhibitors against the factor they are missing. Hemophilia is a serious bleeding disorder and patients with hemophilia develop repeated spontaneous CNS, joint and muscle bleeding. Any trauma, even mild events, may cause life-threatening bleeding, and without treatmen
A novel surface protein of the bacterial species Moraxella catarrhalis that displays a high affinity for IgD (MID) was solubilized in Empigen and isolated by ion exchange chromatography and gel filtration. The apparent molecular mass of monomeric MID was estimated to approximately 200 kDa by SDS-PAGE. The mid gene was cloned and expressed in Escherichia coli. The complete mid nucleotide gene seque
Popular Abstract in Swedish Områden som är kontinuerligt utsatta för vinderosion löper stor risk för att erhålla en försämrad jordkvalitet eftersom vinderosion innebär en utsållning av fina fraktioner och humus från jordmånen. För att vinderosion ska inträffa krävs en kombination av vissa väder- och markförhållanden. Flera av dessa är direkt relaterade till klimatet, t ex vindhastighet och jordfukWind erosion is a serious threat to soil resources as it causes depletion of the fine fractions that may result in a less fertile soil. Wind erosion encompasses several processes of which many are related to climate variables. To date, there is little work performed on how wind erosion relates to climate and climate change. In this thesis, atmospheric circulation and wind erosion were analysed to
The original approach to the creation of high-temperature single-electron tunneling systems has been developed based on the use of nanocluster molecules. The morphology and electron tunneling characteristics through single nanocluster molecules organized as highly-ordered monolayer Langmuir-Blodgett films on atomically-flat graphite substrate have been studied experimentally using scanning tunneli
Popular Abstract in SwedishDenna arkeologiska studie syftar till att förstå de neolitiska samhällenas framväxt, organisation och förändring kring de västskånska ådalgångarna vid Saxån-Välabäcken och Lödde å-Kävlingeån. Arkeologiska undersökningar och fornminnesinventeringen har visat att området hyser omfattande lämningar av neolitiska bebyggelsekomplex — i form av bosättningar, gravfält, megalitgThis dissertation deals with Early and Middle Neolithic societies in a valley landscape in western Scania, in the southern part of Sweden. Several archaeological excavations conducted by the National Heritage Board have revealed a great number of Neolithic remains in this region. The sites constitute a substantial continuous sequence from the earliest to the latest phase of the Funnel Beaker Cultu
Den här avhandlingen har som syfte att bidra till att täcka kunskapsluckor om hur tilläggssvårigheter vid attention deficit hyperactivity disorder (ADHD) hos barn förändras och om dessa har ett samband med hur ADHD-problematiken utvecklas under 3 års tid. ADHD är en utvecklingsrelaterad kognitiv funktionsnedsättning som debuterar hos barn och unga, 12 år eller yngre, genom höga nivåer av ouppmärksClarification on how cognitive, executive and emotional functioning contribute to symptom reduction or improved function in childhood attention deficit hyperactivity disorder (ADHD) is needed to find additional treatment methods. The clinical utility of continuous performance test (CPT) (Conners’ CPT-II, QbTest) to complement rating scales in diagnostic assessments and treatment evaluations (QbTes
A search for new phenomena is presented in final states with two leptons and one or no b-tagged jets. The event selection requires the two leptons to have opposite charge, the same flavor (electrons or muons), and a large invariant mass. The analysis is based on the full run-2 proton-proton collision dataset recorded at a center-of-mass energy of s=13 TeV by the ATLAS experiment at the LHC, corres
This chapter provides a reassessment of the waste ‘crises’ in the so-called Land of Fires in Italy and highlights the contribution of local social mobilizations in advancing environmental justice and sustainability concerns. It is based on the long term collaboration between a social scientist and two activists, and it draws from a dialogue of academic and activist knowledge in the tradition of En
INTRODUCTION: In the wait for disease-modifying treatment for Parkinson’s disease (PD), efforts towards improved symptom control and reduced negative effects of PD can result in meaningful change patients. The general efficacy of levodopa-carbidopa intestinal gel (LCIG) in advanced PD has been established, but its effects on dyskinesia need more investigation. The PD Home Diary has been used in cl
The glucose concentration in diluted whole blood has been measured, using a miniaturized thermal biosensor based on the enzyme thermistor principle. The biosensor is a small flow-injection system. A sample volume of 20μ1 is injected into a flow of 50μl/min. The heat produced when the sample passes the enzyme column is measured with a thermistor connected to a Wheatstone bridge. The enzyme column c
The glucose concentration in diluted whole blood has been measured, using a miniaturized thermal biosensor based on the enzyme thermistor principle. The biosensor is a small flow injection system. A sample volume of 20μl is injected into a flow of 50μ1/min. The heat produced when the sample passes the enzyme column is measured with a thermistor connected to a Wheatstone bridge. The enzyme column c
The first few centuries of the second millennium saw drastic changes in Coastal California and the American Southwest. In both areas, systems of internal trade intensified, and social systems sped down a path of increasing complexity. Following Peter Peregrine and Stephen Lekson (2006, 2012), we do not believe that these neighboring developments were purely coincidental. Rather, we see California
X-ray diffractometers primarily designed for surface X-ray diffraction are often used to measure the diffraction from powders, textured materials and fiber-texture samples in 2θ scans. Unlike in high-energy powder diffraction, only a fraction of the powder rings is typically measured, and the data consist of many detector images across the 2θ range. Such diffractometers typically scan in direction
Clonal deconvolution of mutational landscapes is crucial to understand the evolutionary dynamics of cancer. Two limiting factors for clonal deconvolution that have remained unresolved are variation in purity and chromosomal copy number across different samples of the same tumor. We developed a semi-supervised algorithm that tracks variant calls through multi-sample spatiotemporal tumor data. While
The fate of excited charge carriers in metal halide perovskite semiconductors is influenced by energetic disorder and defects. Here, photoluminescence (PL) blinking is used to probe metastable nonradiative (NR) centers and the nanoscale energy landscape. Temporal activation of an NR center creates a local region with increased NR recombination. Activation and deactivation of this local PL quenchin
BACKGROUND: Central venous catheter (CVC) misplacement occurs frequently after right subclavian vein catheterization. It can be avoided by using ultrasound to confirm correct guidewire tip position in the lower superior vena cava prior to CVC insertion. However, retraction of the guidewire during the CVC insertion may dislocate the guidewire tip from its desired and confirmed position, thereby res
The paper analyzes the need for structural change in the Haitian economy, an economy where the majority make their living in agriculture – a sector characterized by a severe erosion problem. It is argued that tourism does not offer any solution, other than possibly in the long run. The only alternative is export-based industrialization, since Haiti is a small and poor country. Its comparative adva
