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Hyperimmunoglobulinaemia D and periodic fever syndrome (HIDS; MIM 260920) is an autosomal recessive disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Diagnostic hallmark of HIDS is a constitutively elevated level of serum immunoglobulin D (IgD), although patients have been reported with normal IgD levels. To de
Semanticrolelabelinghasbecomeakeymodule for many language processing applications such as question answering, information extraction, sentiment analysis, and machine translation. To build an unrestricted semantic role labeler, the first step is to develop a comprehensive proposition bank. However, creating such a bank is a costly enterprise, which has only been achieved for a handful of languages.
Background: To investigate the effect of baseline clinical characteristics and glucocorticoid treatment on temporal artery biopsy (TAB) findings in patients with giant cell arteritis (GCA). Methods: Individuals who developed GCA after inclusion in two population-based health surveys were identified through linkage to the local and the national patient registers. In addition, other patients diagnos
Charge transfer interactions between C60 and the metal surfaces of Ag(111), Cu(111), Au(111) and Pt(111) have been studied using synchrotron-based photoemission, resonant photoemission and X-ray absorption spectroscopies. By placing the X-ray absorption and valence band spectra on a common binding energy scale, the energetic overlap of the unoccupied molecular orbitals with the density of states o
Pharmaceutical packaging is linked to important demographic changes. Aging ofpopulations is one of the demographic changes which has called for more attention, especially in well-developed countries. The increase in life expectancy represents a positive consequence of years of research, development of medications, and improvement in life habits. In spite of that, the growth in the number of people
In relation to traditional modes of research within academic context, there is a recent interest in research methods where artistic practices set a larger part of the managerial guidelines, i. e. where the artist or artwork is not the subject of investigation, but rather the operative agent for the carrying through of a project and for the dissemination of results. These methods are by necessity
Background: Dietary risks today constitute the largest proportion of disability-adjusted life years (DALYs) globally and in Sweden. An increasing number of people today consume highly processed foods high in saturated fat, refined sugar and salt and low in dietary fiber, vitamins and minerals. It is important that dietary trends over time are monitored to predict changes in disease risk. Methods:
Amylin, also named islet amyloid polypeptide (IAPP), is a protein that is processed and released from pancreatic beta-cells in parallel with insulin. Islet amyloid polypeptide is currently studied with regard to a role for insulin resistance in non-insulin-dependent diabetes. To elucidate a possible function of IAPP for impaired glucose tolerance in primary hyperparathyroidism (pHPT), we studied p
Glycoproteins in cerebrospinal fluid (CSF) are altered in Alzheimer's Disease (AD) patients compared to control individuals. We have utilized albumin depletion prior to 2D gel electrophoresis to enhance glycoprotein concentration for image analysis as well as structural glycoprotein determination without glycan release using mass spectrometry (MS). The benefits of a direct glycoprotein analysis ap
GENERAL AIM: To investigate prognostic markers identifying smokers with increased risk of smoking-related diseases in the population. BACKGROUND: Gene variance in the BDNF- respectively CHRNA-gene has been implicated in different smoking behaviours and the risk alleles have also demonstrated an additional risk increase of smoking-related diseases. The Human Epididymis Protein 4 (HE4) is a cancer b
AbstractAim: Although imaging of In vitro labeled leukocytes is commonly used for diagnosing inflammation and infection, data concerning the use of this technique to monitor neutrophil trafficking are scarce. Here we investigated thepotential of 111In-in vitro labeled leukocytes (InWBC) to monitor neutrophil trafficking in an animal model of pulmonary inflammation.Methods: F344 rats were divided i
Purpose: To investigate associated systemic diseases, other conditions, visual outcome, ocular complications and treatment in Swedish patients younger than 50 years with central retinal vein occlusion (CRVO) and reviewing the literature. Methods: Twenty-two patients with CRVO, younger than 50 years, were examined with full-field electroretinography (ERG) within 3 months after a thrombotic event, o
Helianthemum oelandicum var. canescens (Hartm.) Fr. is an endemic taxon with a restricted distribution (less than 10 km2) in the southernmost part of the Baltic island of Öland, SE, Sweden. The taxon varies with respect to stellate hairs. Most plants can be classified into two morphs, the stellated morph (with a dense carpet of stellate hairs on the abaxial surface of the leaves) and the bristled
The severe and unanticipated economic downturn in Indonesia mirrored the regional economic fallout following the 1997 financial crisis. Although it is likely that the crisis in neighboring countries had an adverse impact on Indonesia, the issue has so far received little attention. This paper examines whether contagion from the economic crisis in Thailand triggered the crisis in Indonesia. Evidenc
In the present study, the authors reevaluated the temporal course and properties of neurotrophic activities present in the fluid accumulating in the silicone-chamber model for nerve regeneration. The fluid collected from silicone chambers was tested in four different dissociated neuronal cell cultures. Furthermore, the activity of the chamber fluid was examined, using a cell blot technique. There
The Sösdala find with its exquisite horse equipment is spectacular and testifies to the prominent role of the horse in Iron Age society. Although the remains of the horses themselves are absent, information about the animal's physical characteristics can be found in related finds from elsewhere in Scandinavia. It is possible to infer that the horses do not seem to have expressed much phenotypic va
