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Coagulation Properties of Swedish Red Dairy Milk: Effect of Poor-coagulating Milk, Pasteurization and Fat

Rennet coagulation ability of milk is of utmost importance in cheese manufacturing industry since it is directly related to cheese quality and yield, then translated into economic benefit. This study examined the rennet coagulation ability and composition of milk from individual Swedish Red (SR) cows, the second most common dairy breed in Sweden. Additionally, the study explored how the presence o

Prospective Randomized Clinical Trial Comparing Paclitaxel-Coated Balloon Versus Conventional Balloon Angioplasty in Treating Below the Knee Arterial Lesions in Chronic Limb Threatening Ischemia: The CRURAL DEB Study

Objective: Drug-coated balloons (DCB) might improve the results of below the knee (BTK) angioplasty, but sufficient randomized data comparing DCB and conventional angioplasty in treating patients with chronic limb threatening ischemia (CLTI) are lacking. This study aimed to perform a randomized comparison between a paclitaxel-coated angioplasty balloon catheter and a conventional balloon angioplas

Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer

More than three-quarters of primary breast cancers are positive for estrogen receptor alpha (ER; encoded by the gene ESR1), the most important factor for directing anti-estrogenic endocrine therapy (ET). Recently, mutations in ESR1 were identified as acquired mechanisms of resistance to ET, found in 12% to 55% of metastatic breast cancers treated previously with ET. We analyzed 3217 population-bas

Central nervous system monoaminergic activity in hip osteoarthritis patients with disabling pain : associations with pain severity and central sensitization

Introduction: Monoaminergic activity modulates nociceptive transmission in the central nervous system (CNS). Although pain is the most disabling symptom of osteoarthritis (OA), limited knowledge exists regarding the CNS mechanisms that amplify pain and drive sensitization processes in humans.Objectives:The main objective of this study was to evaluate associations between cerebrospinal fluid (CSF)

Oleogels as controlled delivery systems for probiotics

A new encapsulation strategy for probiotics is highly needed to tackle the challenge of significant viability loss of bacteria during storage and passage through the gastrointestinal system. A new controlled delivery system for probiotics based on EC oleogels is proposed in this thesis. A relatively non-complicated in vitro lipolysis model was established to evaluate the relative conversion from t

Association between habitual dietary taurine intake and the risk of metabolic dysfunction-associated steatotic liver disease : a prospective cohort study

Taurine, an amino sulfonic acid abundant in seafood and meat, has been proposed to have a potential role in the prevention of metabolic dysfunction-associated steatotic liver disease (MASLD) due to its antioxidant and anti-inflammatory properties. However, the association between dietary taurine intake and MASLD remains unclear in human populations. Also, data on dietary taurine intake among adult

Adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colon cancer at high risk of peritoneal carcinomatosis; the COLOPEC randomized multicentre trial

BACKGROUND: The peritoneum is the second most common site of recurrence in colorectal cancer. Early detection of peritoneal carcinomatosis (PC) by imaging is difficult. Patients eventually presenting with clinically apparent PC have a poor prognosis. Median survival is only about five months if untreated and the benefit of palliative systemic chemotherapy is limited. Only a quarter of patients are

Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants.

Capsazepine is known as a transient receptor potential channel vanilloid subfamily 1 (TRPV1) antagonist that inhibits bronchoconstriction evoked in animals by TRPV1 agonists. In this study, effects of capsazepine and chemically related analogues, so called capsazepinoids, were examined in vitro on contractile effects in human small airway preparations. Repeated cycles with 1 h of LTD4-free physiol

Long-term follow-up of the randomized, prospective Scandinavian heart transplant everolimus de novo study with early calcineurin inhibitors avoidance (SCHEDULE) trial

Background: Early substitution of calcineurin inhibitor (CNI) with mammalian target of rapamycin inhibitors has been shown to improve kidney function and reduce intimal hyperplasia in heart transplant (HTx) recipients but data on long-term outcome of such a regime are still sparse. Methods: In the SCHEDULE trial, 115 de novo HTx recipients were randomized to (1) everolimus with reduced exposure of

Analysis of heparan-sulphate chains and oligosaccharides from proliferating and quiescent fibroblasts. A proposed model for endoheparanase activity

Human skin fibroblasts in different growth states were incubated with [3H]glucosamine and/or Na(2)35SO4 and extracted with Triton X-100 for various periods of time. Free heparan-sulphate oligosaccharides and protein-bound heparan-sulphate chains were separated by chromatography on octyl-Sepharose and analyzed. A pool of endogenously produced oligosaccharides, present in the cultured cells and isol

The impact of CCD radiation damage on Gaia astrometry - I. Image location estimation in the presence of radiation damage

The Gaia mission has been designed to perform absolute astrometric measurements with unprecedented accuracy; the end-of-mission parallax standard error is required to be of the order of 10 mu as for the brightest stars (V= 10) and 30 mu as for a G2V-type star of magnitude 15. These requirements set a stringent constraint on the accuracy of the estimation of the location of the stellar image on the

Highly sensitive, stable and selective hydrogen peroxide amperometric biosensors based on peroxidases from different sources wired by Os-polymer : A comparative study

A comparison was made between two plant peroxidases, cationic horseradish peroxidase (HRP) and anionic tobacco peroxidase (TOP), combined with a highly cationic osmium polymer [Os(4,4'-dimethyl-2,2'-bipyridine)2poly(N-vinylimidazole)10Cl]+2/+ ([Os(dmp)PVI]+/2+) to develop highly sensitive, stable and selective hydrogen peroxide biosensors. The two different plant peroxidases were individually immo

Hur påverkas och korrelerar maximal taluppfattning med dead regions?

Syftet med denna studie var att se på prevalensen av dead regions, frekvensområden i cochlea där det inte finns fungerande inre hårceller (lliC), hos en grupp hörselskadade personer. De hörselskadade personerna har undersökts med det nya testet "Diagnosis for de ad regions" utvecklat av Brian Moore et al. (2000). Försökspersonernas resultat av Dead regionstest har sedan korrelerats med r

Nya 5 a § LAS - klar efter många års förhandlingar, men håller den i praktiken?

30 juni 2022 trädde en omfattande ändring av lag (1982:80) om anställ-ningsskydd i kraft. Ändringarna syftade dels till att göra det lättare för ar-betstagare att komma in samt få en trygg anställning på arbetsmarknaden, dels att göra det enklare och mer flexibelt för arbetsgivare att anställa och avsluta anställningar och därmed minska riskerna med att anställa. Bland annat bytte allmän visstidOn June 30, 2022, a comprehensive amendment to the Employment Protec-tion Act (1982:80) came into effect. The changes aimed to make it easier for employees to enter and secure employment in the labor market, as well as to simplify and provide more flexibility for employers in hiring and terminating employment, thereby reducing the risks associated with hiring. Amongst other changes "general f

Direct load control for electricity supply and demand matching - Increasing reliability of wind energy?

In Sweden as well as in The Netherlands energy policy is increasingly aiming at extending the use of renewable sources. In accordance with the targets of the European Union, both countries have formulated national targets for the year 2020. For wind energy these targets are 30.0 TWh of electricity in Sweden and a total installed capacity of 10.0 GW in The Netherlands. Wind is an inflexible, variab

Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation

PURPOSE: Clinical relapse is the major threat for patients with myelodysplastic syndrome (MDS) undergoing hematopoietic stem-cell transplantation (HSCT). Early detection of measurable residual disease (MRD) would enable preemptive treatment and potentially reduced relapse risk.METHODSPatients with MDS planned for HSCT were enrolled in a prospective, observational study evaluating the association b

Unfpa internship vacancy for co ros spring 2021

NOTES FROM 28 JUNE MEETING ON POPULATION & WOMEN AND CHILD HEALTH WITH UNF/UNFIP 1 Internships with UNFPA Country / Regional Offices In Africa and Asia Position: Intern Duration: 1 February – 28 May 2021 Time: The internship will be full time with an expected workload of 40 hours per week Where: UNFPA Country and Regional Offices in Africa and Asia Conditions: The intern will not receive a salary,

https://www.keg.lu.se/sites/keg.lu.se/files/unfpa_internship_vacancy_for_co_ros_spring_2021.pdf - 2026-05-14

11602.full

pnas201006568 11602..11607 Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors Rohit Sachdevaa, Marie E. Jönssona, Jenny Nelandera, Agnete Kirkebya, Carolina Guibentifa, Bernhard Gentnerb, Luigi Naldinib, Anders Björklunda, Malin Parmara, and Johan Jakobssona,1 aDepartment of Experimental Medical Sciences, Wallenberg Neuroscience Center,

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/11602.full_.pdf - 2026-05-14

Sachdeva et al pnas 2010

pnas201006568 1..6 Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors Rohit Sachdevaa, Marie E. Jönssona, Jenny Nelandera, Agnete Kirkebya, Carolina Guibentifa, Bernhard Gentnerb, Luigi Naldinib, Anders Björklunda, Malin Parmara, and Johan Jakobssona,1 aDepartment of Experimental Medical Sciences, Wallenberg Neuroscience Center, Lund Uni

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/sachdeva_et_al_pnas_2010.pdf - 2026-05-14

Nano tsunami.com - nano medicine in depth

...read the wave™ Nano Medicine...Nano Medizin... Nano Geneeskunde...Nano Medicína www.nanoTsunami.com High-powered living DNA cannon We all know that a viral infection can be developed extremely quickly, but in fact it's even more dramatic than that - the process is literally explosive. The pressure inside a virus is 40 atmospheres, and it is just waiting for an opportunity to blow up. The virus

https://www.virus-biophysics.lu.se/sites/virus-biophysics.lu.se/files/nano_tsunami.com_-_nano_medicine_in_depth.pdf - 2026-05-14