Filtyp
The use of temozolomide (TMZ) for the management of aggressive pituitary tumours (APT) has revolutionised clinical practice in this field with significantly improved clinical outcomes and long-term survival. Its use is now well established however a large number of patients do not respond to treatment and recurrence after cessation of TMZ is common. A number of challenges remain for clinicians suc
Running-in process of low metallic brake pads and cast iron discs are investigated using full scale inertia brake dynamometer designed for particle emission studies. The airborne particles are measured using ELPI+ and collected on filters. The pads and disc contact surfaces are studied using microscopy techniques. It is observed that the particle emissions from the new pads and discs are significa
A key challenge in pilot training and performance assessment is the lack of insight into pilot visual behavior. Without this, it is difficult for an instructor to assess, e.g., whether pilots fail because they did not monitor the instruments or because they did not act on them, and whether pilots comply with monitoring aspects of the Standard Operating Procedures. Eye tracking provides the opportu
The objectives of the thesis were to seek a better understanding of polymorphic RBC surface molecules in the Thai, and to investigate the role of certain blood groups in malarial invasion. MALDI-TOF MS was employed in Study I as an efficient method for genotyping to establish the common blood group and platelet antigen genotypes of 396 blood donors. Investigation of outliers identified variation a
We detail here the convergence properties of a new model-independent imaging method, the Lévy expansion, that seems to play an important role in the analysis of the differential cross section of elastic hadron-hadron scattering. We demonstrate, how our earlier results concerning the Odderon effects in the differential cross-section of elastic proton-proton and proton-antiproton scattering as well
The heat flux method is advantageous for obtaining adiabatic stretch-less flame and measuring laminar burning velocity, SL, with low uncertainty. However, its implementation is sometimes hampered by the instability, manifested as cellularity of the flame stabilized over a flat perforated burner. This paper summarizes the approaches of flame cellularity abatement on the heat flux burner, which are
Crystallographic fragment screening (CFS) provides excellent starting points for projects concerned with drug discovery or biochemical tool compound development. One of the fundamental prerequisites for effective CFS is the availability of a versatile fragment library. Here, we report on the assembly of the 1,103-compound F2X-Universal Library and its 96-compound sub-selection, the F2X-Entry Scree
Employing the heuristic of intersectionality, this study analyzes household effects and responses to water shortage in Gaborone, Botswana, focusing on residents’ adaptive capacity and vulnerability. Using data collected through qualitative interviews, we find that households from all socio-economic backgrounds face various effects from water shortage and use numerous strategies to reduce exposure
Lignin is an abundant cell wall component, and it has been used mainly for generating steam and electricity. Nevertheless, lignin valorization, i.e. the conversion of lignin into high value-added fuels, chemicals, or materials, is crucial for the full implementation of cost-effective lignocellulosic biorefineries. From this perspective, rapid screening methods are crucial for time- and resource-ef
In this study, the photoelectrochemical behavior of electrodeposited FeNiOOH/Fe2O3/graphene nanohybrid electrodes is investigated, which has precisely controlled structure and composition. The photoelectrode assembly is designed in a bioinspired manner where each component has its own function: Fe2O3 is responsible for the absorption of light, the graphene framework for proper charge carrier trans
The FLUXNET2015 dataset provides ecosystem-scale data on CO2, water, and energy exchange between the biosphere and the atmosphere, and other meteorological and biological measurements, from 212 sites around the globe (over 1500 site-years, up to and including year 2014). These sites, independently managed and operated, voluntarily contributed their data to create global datasets. Data were quality
Imprinted genes, giving rise to parent-of-origin effects (POEs), have been hypothesised to affect type 1 diabetes (T1D) and rheumatoid arthritis (RA). However, maternal effects may also play a role. By using a mixed model that is able to simultaneously consider all kinds of POEs, the importance of POEs for the development of T1D and RA was investigated in a variance components analysis. The analys
Due to the multiple benefits of biogas systems, the Chinese Government has made great efforts to promote the development of biogas systems in rural China, especially household biogas plants and medium and large scale biogas plants to treat manure and waste water from intensive livestock and poultry farms. This thesis conducts a comprehensive literature review to understand the current situation of
A lot of money is being spent by the governments all over the world in developing and deploying Government to Citizen (G2C) e-government applications. These applications serve the purpose of providing better civic services to the citizens. The success of such applications is frequently heard and witnessed in the developed countries but there is a prevailing concern about the success and adoption o
The thesis is done for the company Gambro which manufactures dialysis products worldwide. The idea of this thesis is to investigate weaknesses of the communication protocol which is used in one of the Gambro dialysis machines, Prismaflex and thereby investigate opportunities to improve the system by using other protocols. The thesis is divided into three major parts. They are the study of Prismafl
Detta arbete handlar om att utveckla och förbättra en försöksuppställning som kan mäta laserinducerad fosforescens både spektralt och tidsupplöst. Ämnet som emitterar fosforescensen befinner sig i en kalibreringsugn som kan värmas till olika temperaturer vilket möjliggör studier av irreversibla åldringsprocesser i ämnet som funktion av temperatur och tid. Fosforescens är den långa efterglöd som fo
