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This article considers state estimation of rigid-body dynamics where the positions q are available to measurement but where the angular velocities ̇or accelerations are not available to measurement. Using a stability-oriented approach to model-based design of state estimation for Euler–Lagrange systems and rigid-body dynamics, state estimation based on position measurement is shown to guarantee se
Repair and replacement strategies using cell replacement or viral gene transfer for neurologic diseases are becoming increasingly efficacious with clinically meaningful benefits in several conditions. An increased understanding of disease processes opens up opportunities for genetic therapies and precision medicine methods aiming at disease modification or repair of lesioned neurologic structures.
A 2015 review of external examining in the UK assessed the effectiveness of the external examining system in safeguarding academic and quality standards in higher education. The development of the Professional Development Course for External Examiners was a key response to the recommendations from this review. This chapter contains an overview of the structure of the course, the key messages commu
Much research aimed at developing measures for normative criteria to guide the assessment of healthcare resource allocation decisions has focused on health maximization, equity concerns and more recently approaches based on health capabilities. However, a widely embraced idea is that health resources should be allocated to meet health needs. Little attention has been given to the principle of need
Alzheimer’s disease can be treated by targeting amyloid-β plaques and diagnosed in vivo by biomarkers, prompting the revision of criteria for the diagnosis and staging of this disease.
Buildings of all types are increasingly becoming complex ‘systems of systems.’ They are subject to evolving societal objectives, new and innovative materials, and in many countries, regulatory ecosystems are having difficulty keeping pace with rapidly changing societal, environmental and technological changes. Two evolving objectives that are stimulating changes to buildings and communities are th
In this work, we consider the problem of localizing multiple signal sources based on time-difference of arrival (TDOA) measurements. In the blind setting, in which the source signals are not known, the localization task is challenging due to the data association problem. That is, it is not known which of the TDOA measurements correspond to the same source. Herein, we propose to perform joint local
Externally bonded reinforcement (EBR) was used to increase load bearing capacity of light weight aggregate concrete (LWA) masonry walls subjected to eccentric axial compression. Ladder type masonry reinforcement, high strength steel wire strips and glass fiber mesh were used for strengthening of eleven, 2.4 m high, 0.5 m long and 0.1 m thick walls. The reinforcement was applied on the dry wall sur
The ability to generate and control movement is essential for human interactions and overall well-being. Neuromuscular impairment caused by neurological injuries and diseases, such as stroke or limb amputation, severely limits the ability of affected individuals to interact with the surrounding environment, necessitating advanced strategies for rehabilitation and restoration of motor function. Vol
Mirrorless optical parametric oscillators (MOPOs) are very attractive parametric devices that rely on the nonlinear interaction of counter-propagating photons to inherently establish distributed feedback, without the use of external mirrors or surface coatings. These devices offer unique spectral and coherence properties that will benefit a large variety of applications ranging from spectroscopy t
Cardiac magnetic resonance (CMR) is the gold standard noninvasive imaging modality to assess tissue characteristics in vivo which gives it a unique advantage in discriminating benign cardiac masses from malignant tumors. CMR also provides visualization of tumor invasion, hemodynamic effects, and location relative to surrounding cardiac and extracardiac structures. These features make CMR an essent
Fire has the potential to create significant impacts on the built environment. Managing this impact is sometimes pursued without consideration of the interface between the natural and technological worlds. However, as society has recognized the impacts of technological development on environmental sustainability, the need for sustainable and resilient development has emerged. To facilitate sustain
Background: Most strokes and cardiovascular diseases (CVDs) are potentially preventable if their risk factors are identified and well controlled. Digital platforms, such as the PreventS-MD web app (PreventS-MD) may aid health care professionals (HCPs) in assessing and managing risk factors and promoting lifestyle changes for their patients. Methods: This is a mixed-methods cross-sectional two-phas
Lifetimes of high-spin states have been measured for 142Gd and 134Nd with EU-ROBALL IV and AFRODITE, respectively, using DSAM. From calculations in the cranked Nilsson-Strutinsky model it was concluded that at the high-spin states of the (+,0)1 band, 142Gd represents a triaxial nucleus rotating around the longest principal axis.
Background: Atopic dermatitis (AD) is a common inflammatory skin disease while the economic burden of AD by severity is not adequately understood. Objective: To estimate the societal economic burden and to identify cost determinants of AD. Methods: In this population-based, controlled cohort study in Sweden, patients with AD were identified through diagnosis codes in primary or secondary care or b
This paper aims to give a short description of Swedish healthcare provision for persons with intellectual and developmental disabilities (IDD). Swedish persons with IDD should have access to the general healthcare system on the same terms as the general population, and thereby enjoy equal opportunities for healthcare of good quality. Reports from government agencies and interest groups, however, d
