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Climate extremes – a study of vulnerability, adaptation, and loss & damage in relation to the 2018 drought, focusing on Southern Sweden

The extreme weather in terms of drought and heat, which prevailed in Northern Europe during the growing season 2018, had serious consequences for agriculture and farmers in Sweden. Many questions regarding farm production came to a head as drought struck directly against farmers land, economy and wellbeing. This paper argues that it is essential to deeper investigate farmer’s and other land user’s

Altered Acylcarnitine Metabolism Is Associated With an Increased Risk of Atrial Fibrillation

Background Atrial fibrillation (AF) is the most common cardiac arrhythmia, but the pathogenesis is not completely understood. The application of metabolomics could help in discovering new metabolic pathways involved in the development of the disease. Methods and Results We measured 112 baseline fasting metabolites of 3770 participants in the Malmö Diet and Cancer Study; these participants were fre

Influence of the number of injections on piston heat rejection under low temperature combustion conditions in an optical compression-ignition engine

New combustion concepts are being investigated to develop cleaner engines. One of the most promising is partially premixed combustion. The mechanisms of this combustion mode and its impact on performance and emissions have been studied in the previous years. Nevertheless, little research has been done from the point of view of heat transfer. In particular, the influence of the injection strategy o

"Elöverkänslighet" : En förklaringsmodell, några karakteristika hos drabbade och effekten av psykologisk behandling med kognitiv-beteendeterapeutiska metoder

The thesis examines various aspects of "electricity hypersensitivity" (EH). An empirical investigation of a group of persons suffering from EH was carried out, a part of the group being treated psychologically according to cognitive- behavioural principles in a controlled outcome study. The major findings concern an explanatory-model of EH, the the assessment of characteristics of EH-sufferers and

Risk of second cancer in Hodgkin lymphoma survivors and influence of family history

Purpose: Although advances in Hodgkin lymphoma (HL) treatment have led to improved disease-free survival, this has been accompanied by an increased risk of second cancers. We sought to quantify the second cancer risks and to investigate the impact of family history. Patients and Methods: Using the Swedish Family-Cancer Project Database, we identified 9,522 individuals with primary HL diagnosed bet

A future for the past of spectacular desert vernacular

Desert vernacular architecture is a product of a sustainable building cycle. Desert local inhabitants inherited the traditional way of building from their ancestors developed and then transferred knowledge from one generation to another. This building and cultural cycle is about to disappear in many desert vernacular settlements of the world. Global ambitions and socio-economic developments are so

Causes and consequences of mesenteric embolization after endovascular aorto-iliac intervention - a nested case control study

Background: Causes and consequences of mesenteric embolization after endovascular aorto-iliac procedures have not been studied adequately. Methods: Consecutive patients with mesenteric embolization after endovascular aorto-iliac intervention between 2011 and 2015 (case-group, n = 9) were investigated and compared with age, gender and procedure-matched random controls (n = 36). Results: Compared to

Subcritical water extraction of nutraceuticals with antioxidant activity from oregano. Chemical and functional characterization

In the present work, oregano leaves (Origanum vulgare L.) are explored as natural source of nutraceuticals with antioxidant activity. To do this, subcritical water extraction (SWE), a new environmentally friendly technique, is employed as extraction procedure and HPLC coupled to DAD is used for the chemical characterization of the extracts. Moreover, the radical scavenging 1,1-diphenyl-2-picrylhyd

Preference-based valuation of treatment attributes in haemophilia A using web survey

Introduction: Clinical trials have shown promising results for extended half-life factor VIII concentrates but little is known about individuals' valuation of haemophilia treatment attributes. Aim: To assess patient/caregiver and population valuation of treatment attributes of prophylactic regimens for people with severe haemophilia A. Methods: Members ≥16 years of the Swedish Haemophilia Society

Kynurenine metabolites predict survival in pulmonary arterial hypertension : A role for IL-6/IL-6Rα

Activation of the kynurenine pathway (KP) has been reported in patients with pulmonary arterial hypertension (PAH) undergoing PAH therapy. We aimed to determine KP-metabolism in treatment-naïve PAH patients, investigate its prognostic values, evaluate the effect of PAH therapy on KP-metabolites and identify cytokines responsible for altered KP-metabolism. KP-metabolite levels were determined in pl

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The present population based cohort study investigates the association between alcohol intake and cancer of the upper digestive tract. The design was prospective with baseline assessment of intake of beer, wine and spirits, smoking habits, educational level and 2-19 years' follow up on risk of upper digestive tract cancer (oropharyngeal and oesophageal). During a mean follow up of 13.5 years, 156

Experimental and numerical study of flow and ignition and lean blowout characteristics of jet-cooled wall flameholder in a dual-mode combustor

The wall flameholder is one of the credible alternatives to realize pilot ignition in augmented/ramjet combustors. To overcome the ablation for a long-term operation, two types of jet cooling, external-inhaled air and pressure-driven jet cooling, are proposed for the wall flameholder. In this work, the flow and combustion process in a laboratory scale rig is studied for different cooling schemes a

Phenotypic plasticity in floral scent in response to nutrient, but not water, availability in the perennial plant Arabis alpina

Floral scent is an important mediator of plant–pollinator interactions. Multiple recent studies report ample intraspecific scent variation among populations and individuals. Yet, few studies have eastimated effects of phenotypic plasticity on floral scent in response to differing environmental factors. In this study, we investigated the effects of nutrient and water availability on floral scent in

Variation in technical properties of granitic rocks with metamorphic conditions

Granitic rocks constitute a global raw material key asset for aggregate production. Their technical performance is, however, highly variable and knowledge on the aggregate functionality of granites in different geological settings is incomplete. This study investigates systematic variations in resistance to fragmentation (Los Angeles value) and wear (Micro-Deval value) for granitic rocks along a 1

Cross-country differences in preferences for leisure

The starting point of this paper is to document considerable cross-country variation in the “labor wedge”, a common measure of labor market frictions. Its variation is theoretically isomorphic to differences in a preference-for-leisure parameter. The paper proceeds to investigate what might explain the variation. It presents three separate empirical exercises supportive of the view that, to a subs

Time-dependent dephasing and quantum transport

The investigation of the phenomenon of dephasing assisted quantum transport, which happens when the presence of dephasing benefits the efficiency of this process, has been mainly focused on Markovian scenarios associated with constant and positive dephasing rates in their respective Lindblad master equations. What happens if we consider a more general framework, where time-dependent dephasing rate

Single-cell transcriptional profiling informs efficient reprogramming of human somatic cells to cross-presenting dendritic cells

Type 1 conventional dendritic cells (cDC1s) are rare immune cells critical for the induction of antigen-specific cytotoxic CD8+ T cells, although the genetic program driving human cDC1 specification remains largely unexplored. We previously identified PU.1, IRF8, and BATF3 transcription factors as sufficient to induce cDC1 fate in mouse fibroblasts, but reprogramming of human somatic cells was lim