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A low intake of calcium is widely considered to be a risk factor for future fracture. The aim of this study was to quantify this risk on an international basis and to explore the effect of age, gender and bone mineral density (BMD) on this risk. We studied 39,563 men and women (69% female) from six prospectively studied cohorts comprising EVOS/EPOS, CaMos, DOES, the Rotterdam study, the Sheffield
Popular Abstract in Swedish Sjukdomar som drabbar hjärtats kranskärl och ger upphov till bland annat hjärtinfarkt är den vanligaste dödsorsaken både i Sverige och i resten av världen. Avsikten med denna avhandling är att ge en bild av livskvaliteten hos hjärtpatienter samt att ta upp problem inom medicinsk etik, som berör dessa patienter. Män och kvinnor som vårdats för hjärtinfarkt vid UniversiteOne month and one year after acute myocardial infarction (AMI) (n=296), coronary artery bypass grafting (CABG) (n=99) and percutaneous coronary intervention (PCI) (n=18) patients completed a questionnaire for self-assessment of quality of life (QoL) during the period 1989?1991. Patients differed from age- and sex-matched controls (n=88) in both somatic and emotional dimensions, but less after one
Popular Abstract in Swedish Talarålder är en viktig paralingvistisk egenskap i tal, som bör beaktas vid studiet av fonetisk variation. Kunskap om talarålder kan användas för att förbättra talteknologiska tillämpningar såsom automatisk taligenkänning och talsyntes. Föreliggande doktorsavhandling beskriver sex studier som undersökt ett flertal aspekter av den åldersrelaterade variationen i tal. NärSpeaker age is an important paralinguistic feature in speech which has to be considered in the study of phonetic variation. Knowledge about this feature may be used to improve speech technology applications, e.g. automatic speech recognition and speech synthesis. The present thesis describes six studies of several phonetic aspects of age-related variation in speech. As the speech production mecha
Background: Differentiated thyroid carcinoma (DTC) is occurring three times more frequently in females than in males. However, the underlying biological mechanisms driving this discrepancy remain poorly understood. To investigate the causal role of sex hormones and reproductive factors in the risk of DTC, we implemented a two-sample Mendelian randomization (MR) analysis. Methods: We utilized genom
Externally bonded reinforcement (EBR) was used to increase load bearing capacity of light weight aggregate concrete (LWA) masonry walls subjected to eccentric axial compression. Ladder type masonry reinforcement, high strength steel wire strips and glass fiber mesh were used for strengthening of eleven, 2.4 m high, 0.5 m long and 0.1 m thick walls. The reinforcement was applied on the dry wall sur
The provision of safe care is complex and difficult to achieve. Awareness of what happens in real time is one of the ways to develop a safe system within a culture of safety. At Great Ormond Street Hospital, we developed and tested a tool specifically designed for patients and families to report harm, with the aim of raising awareness and opportunities for staff to continually improve and provide
Purpose: The study explores how organizational space and situational strength influence bystanders’ intentions to intervene in workplace bullying within the healthcare sector. Design/methodology/approach: The research employs vignette-based interviews with 24 healthcare professionals from various medical fields in Sweden. The vignettes depict different bullying scenarios occurring in various spati
C4b-binding protein (C4BP) is a multimeric glycoprotein in plasma with important regulatory functions in the complement system. It occurs in two forms, as free protein and in a non-covalent bimolecular complex with the vitamin K-dependent protein S. Protein S is an important anticoagulant and enhances the rate of inactivation by activated protein C of blood coagulation factors, Va and VIIIa. Prote
OBJECTIVES: To describe functional and structural impairments of the pulmonary system in middle-aged people with cervical and upper thoracic spinal cord injuries (SCI), and compare findings to the general population. To determine if the neurological level of injury (NLI) is related to functional and structural impairments, and if age is related to structural impairments.DESIGN: Cross-sectional stu
The built environment is important to achieve a sustainable society. From a sustainability perspective, refurbishment can be preferable to building anew. A significant proportion of the built environment needs to be refurbished. Refurbishment projects also provide the opportunity to proactively upgrade the working environment for users during operation and use.Research concerning the working envir
This thesis applied magnetic resonance imaging (MRI) to investigate to what extent very preterm birth due to early onset fetal growth restriction (FGR) impacts the cardiovascular system and kidneys in adolescence. The thesis further investigated whether FGR exacerbates the organ-specific effects of very preterm birth.Study I validated a widely available non-contrast enhanced MRI method for quantif
In modern society, the consumption of fossil fuels has been increasing drastically, leading to significant emissions of carbondioxide (CO2), air pollution, global warming, and political and economic imbalances. This has increased the interest inrenewable and sustainable energy sources such as wind- and hydropower, solar energy, and in energy conversion by fuel celltechnology, and water electrolyse
• Purpose: To assess whether distal radius fracture (DRF) malunion is associated with greater patient-reported disability. • Methods: We searched PubMed, EMBASE, and Cochrane databases up to 21 May 2023. Two reviewers independently screened retrieved titles/abstracts and assessed the full text of potentially eligible articles to identify cohort studies and randomized controlled trials reporting ou
Emotional communication, especially through social media platforms, has become a contemporary populist threat. While this phenomenon has been studied in for example news media and social movements, we know less about its influence on civil society organizations, despite their pluralism being a centerpiece in a vibrant democracy. More specifically, we do not know if social media make civil society
Popular Abstract in Swedish Kräftors påverkan på födovävar i dammar och sjöarThis thesis examines how freshwater crayfish affect community interactions in benthic food webs. I have mainly studied the influence of the introduced signal crayfish (Pacifastacus leniusculus) on littoral communities, but also the influence of the native noble crayfish (Astacus astacus). Overall, the results show that both crayfish species are omnivores having strong direct and indirect effects o
Popular Abstract in Swedish Forskningsprojektet som rapporteras i denna avhandling har två övergripande mål. Det första målet är att utveckla testinstrument avsett för avancerade svenska inlärare av engelska, som genererar reliabla och valida testpoäng kopplat till receptiv kunskap avseende engelska kollokationer som en specifik förmåga. Med kollokationer avses konventionaliserade och frekvent förThe research reported in this thesis has two main aims. The first aim is to develop tests capable of yielding reliable and valid scores of receptive knowledge of English collocations as a single construct, for use with advanced L2 learners of English. Collocations are seen as conventionalized, recurring combinations of words, and the targeted types are adjective + NP and verb + NP. The second aim
Anaerobic digestion (AD) offers considerable potential in the production of energy from renewable sources, and is being increasingly recognised as a sustainable technology for the treatment of waste. The production of energy from waste such as municipal solid waste (MSW), lipid-rich waste, and agricultural biomass and waste may play an important role in the production of renewable energy given the
Interest in the distinctive features of early Christian manuscripts (e.g. codex format, staurogram, nomina sacra, handwriting, and lectional signs) has increased significantly over the last decade. They are no longer merely identified and compared, but also put into a sociocultural context of early Christian scribal habits and reading culture. Similarly, more attention is constantly being directed
Swedish emigration to America is a topic that does not hold a major position in Swedish historical research anymore. At one time, during the 1960s and 1970s, there were a major research project, Sweden and America after 1860, that focused primarily on the reasons of the migration, the demographics of the migration and to some extent what happened to the emigrants in America. The research project d
