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The glycosphingolipid (GSL) antigens in the clinically important P1PK and GLOB blood group systems are present on erythrocytes as well as other tissues and are so-called histo-blood group antigens. Blood group antigens of carbohydrate nature are products of enzymes, so-called glycosyltransferases, adding sugars in a step-wise manner to an acceptor substrate. Presence or absence of the P1PK and GLO
Objective. The first successful pregnancy after heart transplantation was reported in 1988. Worldwide experience with heart and heart/lung transplanted (H-HLTx) pregnant women is limited. To expand this knowledge the collaborating Nordic thoracic transplant centers wanted to collect information on all such pregnancies from their centers. Design. Information was retrospectively collected on all H-H
In this paper railway accident investigation reports issued by the national accident investigation boards in three Scandinavian countries during a 2-year period have been systematically studied. Content analysis of attributed causes in these reports reveals a considerable emphasis on physical processes, actor activities and equipment (the microlevel). Much less attention is paid to organisational
Two acid deposition scenarios were simulated for six European forest sites situated in Germany, Denmark, Russia, Switzerland, Spain and Ireland. Three models were used in combination; the RAINS (Regional Acidification INformations and Simulation) model, the SAFE (Simulating Acidification in Forest Ecosystems) model and the MakeDep model. The scenarios used were based on results from international
Salvage hypospadias surgery is performed after failed primary reconstruction. Several treatment strategies have been suggested, all with pros and cons. The aim of this study was to evaluate our treatment algorithm for primary hypospadias repair applied to secondary cases in which a salvage procedure is indicated and, most importantly, local tissue is present. The algorithm was applied to 36 consec
Professor Contact details Email: markku [dot] rummukainen [at] mgeo [dot] lu [dot] se Mobile: +46 70 818 68 89Organisation Department of Earth and Environmental Sciences (MGeo) Visiting address: Sölvegatan 12, Lund Room number: 522 Service point: 16 WebpageMarkku Rummukainens profile in Lund University research portalOther affiliations Member of Strategic Research Area MERGE: ModElling the Regiona
https://www.nateko.lu.se/markku-rummukainen - 2026-06-16
The number of CT examinations giving a relatively high patient exposure is increasing. It is therefore important to optimize the imaging conditions at these investigations. Many steps have been taken to reduce the radiation doses in CT examinations. Currently much work is related to iterative image reconstruction methods as alternative to the filtered back projection method. The aim of this work w
Salt-inducible kinase (SIK) 3 is a virtually unstudied, ubiquitously expressed serine/threonine kinase, belonging to the AMP-activated protein kinase (AMPK)-related family of kinases, all of which are regulated by LKB1 phosphorylation of a threonine residue in their activation (T)-loops. Findings in adrenal cells have revealed a role for cAMP in the regulation of SIK1, and recent findings suggest
Popular Abstract in Swedish Prostatacancer är idag den vanligaste sjukdomen hos män, och är den cancer form som leder till flest dödsfall bland män i Sverige (av de män som får diagnosen avlider 35% på grund av sjukdomen). Det har visats att risken att utveckla prostatacancer påverkas av ålder, etnicitet och diet (bla asiatisk mat och tomater verkar ha skyddande effekt), men också av genetiska fakProstate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. Lately, the family has been expanded to contain 12 new genes, KLK4–KLK15, that are situated at the same locus
Popular Abstract in Swedish Denna avhandling handlar om hjälpande och framförallt om givande till välgörenhet. De två centrala frågorna som ställs handlar om när vi hjälper (i vilka situationer hjälper vi mer eller mindre?) och om varför vi hjälper i dessa situationer (vilka sorters känslor och tankar gör oss mer motiverade att hjälpa?) Hjälpeffekter: När hjälper vi? Frågan om när vi hjälper hanThe overarching purpose of this thesis was to investigate if different helping effects can be specifically linked to different psychological mechanisms. Helping effects (i.e. the when of helping) refer to situational differences that can increase or decrease the probability of helping. The three helping effects in focus in this thesis, were (1) the identifiable victim effect (the tendency to be
In this paper we show that several metals, elements and energy resources are about to run into scarcity within the next decades, and most elements within some centuries. A new global systems model was assembled to analyse this scarcity as a continuation of the model used in the Limits-to-Growth World3 model. We show that this scarcity will lead to “peak wealth”, “peak population”, “peak costs”, “p
Summary: Reduction of the cerebral perfusion pressure caused by vessel occlusion or stenosis is a cause of neurological symptoms and border-zone infarctions. The aim of this article is to describe perfusion patterns in hemodynamic stroke, to give a practical approach for the assessment of colour encoded CT- and MR-perfusion maps and to demonstrate the clinical use of comprehensive imaging in the w
Permutational Grammar, PG, is a grammar inspired by the Free Word Order grammar, FOG, presented in Vladimir Pericliev & Alexander Grigorov 1992. Some languages, notably Latin, are said to have free word order, see e.g. Siewierska 1988. The name Permutational Grammar is derived from the use of permutations in order to generate order variation. The general problem to be solved by FOG and PG is t
Tensins are large intracellular proteins believed to link the extracellular matrix to the cytoskeleton via integrins. Tensins are multidomain proteins consisting of homologous C1, PTPase, C2, SH2 and PTB domains. Full-length Tensin proteins can undergo cleavage inside cells, thus yielding domains in isolation that may have discrete subcellular localisations and downstream effects. We expressed dif
BACKGROUND: Child Abuse and Neglect (CAN) is a severe threat to children's health and well-being worldwide. Since oral and dental health are indicators of general health, dentists and dental hygienists are in a favorable position to identify potential cases of CAN.OBJECTIVE: This study aims to investigate the caries experience in primary and permanent dentition in children where physical abuse was
ObjectivesResearch on personality seeks to understand what makes people similar or distinct from another. However, there is still a limited understanding of processes that underpin an individual’s personality, such as interactions with other psychological dispositions such as trait mindfulness. Elucidating the unique relationships between mindfulness and personality traits with network analysis ca
OBJECTIVE: Our study aims to evaluate hypertensive case management in South Africa's public health sector using simulated patients.METHOD: Our study describes interactions between hypertensive simulated patients and primary healthcare workers at 39 public sector healthcare facilities in two metropolitan centres in the Eastern and Western Cape Provinces of South Africa. Our analysis focus on 97 int
Clonal hematopoiesis of indeterminate potential (CHIP) is a common form of age-related somatic mosaicism that is associated with significant morbidity and mortality. CHIP mutations can be identified in peripheral blood samples that are sequenced using approaches that cover the whole genome, the whole exome, or targeted genetic regions; however, differentiating true CHIP mutations from sequencing a
Despite laws, policies, and political visions to create cities and societies for all, barriers still exclude people from using buildings and public places. The commitments made in global agreements such as the Convention on Rights for Persons with Disabilities (CRPD) and the 2030 Agenda for Sustainable Development require significant changes in urban planning to meet the variety of needs and condi
