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Estimating and analyzing savannah phenology with a lagged time series model
Savannah regions are predicted to undergo changes in precipitation patterns according to current climate change projections. This change will affect leaf phenology, which controls net primary productivity. It is of importance to study this since savannahs play an important role in the global carbon cycle due to their areal coverage and can have an effect on the food security in regions that depend
A first-in-human, double-blind, randomised, placebo-controlled, dose ascending study of intra-articular rhFGF18 (sprifermin) in patients with advanced knee osteoarthritis
OBJECTIVES: To evaluate the safety of intra-articular sprifermin (primary), and to evaluate systemic exposure, biomarkers, histology, and other cartilage parameters in patients with advanced osteoarthritis (OA).METHODS: This was a first-in-human, double-blind, randomised, placebo-controlled trial of single and multiple ascending doses of sprifermin from 3-300 μg in knee OA patients scheduled for t
Primary midwives' experiences of collegial midwifery assistance during the active second stage of labor : Data from the Oneplus trial
Background: Collegial midwifery assistance during the active second stage of labor that involves a second midwife being present has been shown to reduce severe perineal trauma (SPT) by 30%. The aim of this study was to investigate primary midwives' experiences of collegial midwifery assistance with the purpose of preventing SPT during the active second stage of labor. Methods: This study uses an o
The development of blood protein profiles in extremely preterm infants follows a stereotypic evolution pattern
BACKGROUND: Preterm birth is the leading cause of neonatal mortality and morbidity. Early diagnosis and interventions are critical to improving the clinical outcomes of extremely premature infants. Blood protein profiling during the first months of life in preterm infants can shed light on the role of early extrauterine development and provide an increased understanding of maturation after extreme
Performance Evaluation of QUIC vs TCP for Cloud Control Systems
QUIC is a UDP-based transport layer protocol developed by Google that boasts lower latency performance than TCP. However, different conclusions have been reported regarding its performance due to variations in targeted applications and experimental setups. This leads to our conclusion that protocol performance evaluation should be heavily dependent on the QoS requirements of the target application
Professionalization in welfare-oriented civil society organizations : Comparison of board chairs and executive directors concerning motives for engagement and leadership ideals
The implications of professionalization of civil society organizations have seldom been explored in relation to the governance structure of organizations’ and leaders’ different terms of engagement. This study draws on a survey targeting leaders of Swedish welfare-oriented civil society organizations (N. 140) and compares the motives for engagement and leadership ideals of two groups of leaders: b
Living in Two Worlds – Children's Experiences After Their Parents' Divorce – A Qualitative Study
Purpose: The aim of this study was to gain a deeper understanding of how children living in two homes after parents' separation experience their everyday lives. Design and Methods: An inductive qualitative design was chosen for the study using a hermeneutic phenomenological approach. Twelve children aged 10–13 years, and living in two homes, were interviewed. The data analysis used the four fundam
Effects of a multifaceted intervention QI program to improve ICU performance
Background To benefit from the increasing clinical evidence, organisational changes have been among the main drivers behind the reduction of ICU mortality during the last decade. Increasing demand, costs and complexity, amplifies the need for optimisation of clinical processes and resource utilisation. Thus, multidisciplinary teamwork and critical care processes needs to be adapted to profit from
Fungal extracellular polymeric substance matrices – Highly specialized microenvironments that allow fungi to control soil organic matter decomposition reactions
Filamentous fungi play a key role in the terrestrial carbon cycle as they are the primary decomposers of lignocellulose in soil organic matter (SOM). Fungi secrete a wide range of oxidative and hydrolytic enzymes, and generate radicals through extracellular secondary metabolites to decompose SOM. To study fungal decomposition of SOM, the activities of isolated enzymes are typically studied as prox
Prevention of posttraumatic osteoarthritis at the time of injury : Where are we now, and where are we going?
This overview of progress made in preventing post-traumatic osteoarthritis (PTOA) was delivered in a workshop at the Orthopaedics Research Society Annual Conference in 2019. As joint trauma is a major risk factor for OA, defining the molecular changes within the joint at the time of injury may enable the targeting of biological processes to prevent later disease. Animal models have been used to te
Microalbuminuria and retinopathy in adolescents and young adults with type 1 and type 2 diabetes
Aim: To estimate the occurrence of complications related to early-onset type 2 diabetes compared with type 1 diabetes. Methods: All individuals registered in the Swedish Pediatric Quality Diabetes Register and the Swedish National Diabetes Register with type 2 diabetes diagnosis at 10 to 25 years of age between 1996 and 2014 (n = 1413) were included. As controls, individuals with type 1 diabetes w
Invasive heritage: Risks and values in cultivation
Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. Certain plant varieties have proved to be particularly vital, have a long history as cultivars, and are today understood as heritage plants. Many have spread over centuries and are today regarded as ‘belonging’ and as more or less Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. Certain plant varieties have proved to be particularly vital, have a long history as cultivars, and are today understood as heritage plants. Many have spread over centuries and are today regarded as ‘belonging’ and as more or less
Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia : Results from the HEAT-AML trial
Background: Treatment of newly diagnosed acute myeloid leukaemia (AML) is based on combination chemotherapy with cytarabine (ara-C) and anthracyclines. Five-year overall survival is below 30%, which has partly been attributed to cytarabine resistance. Preclinical data suggest that the addition of hydroxyurea potentiates cytarabine efficacy by increasing ara-C triphosphate (ara-CTP) levels through
Test-retest reliability of physical activity questionnaires in Parkinson’s disease
Background: People with Parkinson’s disease are less physically active than controls. It is important to promote physical activity, which can be assessed using different methods. Subjective measures include physical activity questionnaires, which are easy and cheap to administer in clinical practice. Knowledge of the psychometric properties of physical activity questionnaires for people with Parki
Avbrott i kritiska flöden – Invånares tolerans- och acceptansnivåer
Nyckelaktörer i samhället tror att invånare är dåligt förberedda inför avbrott i el, värme, vatten och telekom, något som en enkätstudie riktad mot Helsingborgs invånare bekräftar. Framför allt sårbara är invånare för avbrott i el och vattentillförsel, vilket majoriteten vill ska prioriteras vid avbrott som inträffar samtidigt. Samhällsaktörers bedömning av hur väl invånare kan hantera avbrotten s
Informellt ministerstyre - Hur informella kontakter mellan regeringen och dess underlydande myndigheter förhåller sig till regeringsformen
Sverige är ett tämligen unikt land när det kommer till den offentliga förvaltningen. Regeringens underlydande myndigheter har lydnadsplikt, samtidigt som myndigheterna ska vara självständiga. Sverige har inget ministerstyre, utan det är regeringen som kollektivt kan ge direktiv till sina myndigheter. Uppsatsen ämne berör i vilken mån regeringen kan använda sig av så kallade informella kontakter, ”Sweden is a rather unique country when it comes to public administration. The government agencies must show obedience towards the government, but the government agencies are at the same time independent from the government. Sweden does not allow ministerial rule, instead the governmet is forced to give directives collectively. The main subject of the essay is to ascertain in what way the governmen
Investigation of Physical Stability of Baobab Pulp Emulsion – for Food Application
Background and objectives Baonaise is a novel plant-based savoury sauce. Baonaise sauce base (BSB) is produced from baobab fruit pulp. Creaming and phase separation were observed in Baonasie from previous studies at the company. In this study, concentration, temperature and type of oil, speed and time of mixing were studied to investigate the factors influencing the physical stability of baobab p
Investigation of Physical Stability of Baobab Pulp Emulsion – for Food Application
Background and objectives Baonaise is a novel plant-based savoury sauce. Baonaise sauce base (BSB) is produced from baobab fruit pulp. Creaming and phase separation were observed in Baonasie from previous studies at the company. In this study, concentration, temperature and type of oil, speed and time of mixing were studied to investigate the factors influencing the physical stability of baobab p
Media Path to Identity : The Journey of Vietnamese Young Generation Making Sense of Their Identity in the Media Space
Recent research has noticed that the picture of the second-generation immigrants negotiating their identity in media space is different and far more complex than the first generation. With their emergence in the new age of digitalisation, the second-generation immigrant is offered more media choices and freedom of access to the two most important cultural sets of host and homeland country to make
