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Background: Bone Scan Index (BSI) derived from 2D whole-body bone scans is considered an imaging biomarker of bone metastases burden carrying prognostic information. Sodium fluoride (NaF) PET/CT is more sensitive than bone scan in detecting bone changes due to metastases. We aimed to develop a semi-quantitative PET index similar to the BSI for NaF PET/CT imaging and to study its relationship to BS

Introduction: Minimally invasive methods to reduce menorrhagia were introduced in the 1980s and 1990s. Transcervical endometrial resection (TCRE) and endometrial ablation (EA) are two of the most frequently used methods. As none of them can guarantee a complete removal of the endometrium, there are concerns that the remaining endometrium may develop to endometrial cancer (EC) later in life. The pr

BACKGROUND: The management of diverticular disease and its complications are an increasing burden to the health system. The natural history of conservatively managed diverticular abscesses (Hinchey I and II) is poorly described and it remains open to debate whether subsequent sigmoid resection is indicated after conservative management. This observational study compares outcomes of patients treate

The length of the growing season for deciduous trees in temperate and boreal forests is determined by the timing of bud burst and autumn senescence. It is generally assumed that a warmer climate leads to a longer growing season due to earlier bud burst and delayed autumn senescence and thereby increased gross primary production (GPP) of forests. In this study, we analysed past (1873–1951) and curr

Anthropogenic nitrogen deposition is widely considered to increase CO2 sequestration by land plants on a global scale. Here, we demonstrate that bedrock nitrogen weathering contributes significantly more to nitrogen-carbon interactions than anthropogenic nitrogen deposition. This working hypothesis is based on the introduction of empirical results into a global biogeochemical simulation model over

Vad hände med innebörden av ordet "otrygghet", ett ord med gamla svenska rötter och en tidigare etablerad innebörd, när det amerikanska forskningsfältet "Fear of Crime" introducerade i Sverige och översattes till "Otrygghet"? Syftet med denna avhandling är att beskriva trygghetsforskningens uppkomst, etablering och expansion i Sverige, i syfte att besvara frågor om forskningsdiskursens funktion, sThe purpose of this dissertation is to construct an historical account of the emergence, establishment, and expansion of fear of crime research in Sweden. This dissertation aims to answer questions about the function, spread, and high level of institutional engagement of fear of crime research by analyzing the literature and examining the methodological, theoretical, and epistemological origins of

Transcatheter aortic valve replacement (TAVR) is a rapidly growing field. Short-term safety and efficacy of these procedures have been studied extensively. However, little is known about the safety of these devices over time. Stroke is one feared long-term complication, and an increased stroke rate could affect guidelines for treating both the aortic stenosis and choosing antithrombotic therapy af

Research into repair within the circular economy (CE) typically focuses on technical aspects of design, policy, and markets, and often assumes or implies simplified conditions for the user/owner and the product-system to explain the barriers to scaling repair activities. By integrating life cycle and temporal dimensions (time-sequence) into a broad System of Repairability framework, we demonstrate

Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. In gardens, vitality is often regarded as an asset and a reason to cultivate certain plants. Many varieties that have spread over centuries are today regarded as ‘belonging’, as more or less ‘natural’, and even as heritage plants. Gardeners have always used plants of different origins, moving them around to new environments, working hard to make the plants survive and thrive under new conditions. In gardens, vitality is often regarded as an asset and a reason to cultivate certain plants. Many varieties that have spread over centuries are today regarded as ‘belonging’, as more or less ‘natural’, and even as heritage plants.

Here we discuss the current state of knowledge of terrestrial planet formation from the aspects of different planet formation models and isotopic data from 182Hf-182W, U-Pb, lithophile-siderophile elements, 48Ca/44Ca isotope samples from planetary building blocks, recent reproduction attempts from 36Ar/38Ar, 20Ne/22Ne, 36Ar/22Ne isotope ratios in Venus’ and Earth’s atmospheres, the expected solar

Corynebacterium is a genus that can contaminate blood cultures and also cause severe infections like infective endocarditis (IE). Our purpose was to investigate microbiological and clinical features associated with contamination and true infection. A retrospective population-based study of Corynebacterium bacteremia 2012–2017 in southern Sweden was performed. Corynebacterium isolates were species

Cardiovascular diseases (CVDs) remain a leading cause of death globally. According to the American Heart Association, approximately 19.1 million deaths were attributed to CVDs in 2020, in particular, ischemic heart disease and stroke. Several known risk factors for CVDs include smoking, alcohol consumption, lack of regular physical activity, and diabetes. The last decade has been characterized by

Gaze following refers to the ability to co-orient with others’ gaze directions. Ontogenetic studies on gaze following in animals have predominantly used human experimenters as demonstrators. It is, however, likely that developing animals are initially more attuned to individuals from their own species, which might result in differences in the ontogenetic onset of gaze following with human and cons

Saving peak powers in the heating systems have been in focus for some years now. Sweden has more and more cooling systems with an increase in cooling also in residential buildings. The cooling power is much more expensive than the heating power and the cost of cooling is largely driven by installed power. Therefore, there is a relative advantage of reducing the cooling power instead of heating pow

Cognitive behavioral therapy (CBT) is an efficacious therapy for youth anxiety disorders. Caregivers are key stakeholders in youth therapy, and their feedback on treatment can help to inform intervention personalization. This mixed-methods study applied a systematic inductive thematic analysis to identify themes among most- and least-liked CBT features reported by caregivers using open-ended respo

Objectives To investigate factors associated with severe COVID-19 in people with psoriasis (PsO), psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA). Methods Demographic data, clinical characteristics and COVID-19 outcome severity of adults with PsO, PsA and axSpA were obtained from two international physician-reported registries. A three-point ordinal COVID-19 severity scale was define

The Vimmerby Moraine is the only significant ice-marginal moraine on the eastern side of southern Sweden, but no detailed studies exist on its formation during the final deglaciation of the Fennoscandian Ice Sheet. Through ground-penetrating radar surveys and detailed sediment logging, we provide evidence for an active, oscillating ice margin during the formation of the Vimmerby Moraine, suggestin

Modeling of riverine dissolved organic carbon (DOC) dynamics is of great importance for the global carbon budget. Impoundment interception changes the travel time of water and DOC from upslope contributing areas, exerting substantial influence on riverine DOC dynamics in the catchments with many impoundments. However, the impact of impoundment interception representation on riverine DOC modeling h

This study analyzes the relationship between drought processes and crop yields in Moldova, together with the effects of possible future climate change on crops. The severity of drought is analyzed over time in Moldova using the Standard Precipitation Index, the Standardized Precipitation Evapotranspiration Index, and their relationship with crop yields. In addition, rainfall variability and its re

Chronic breathlessness is a common and distressing symptom, negatively impacting physical function and quality of life. Many individuals presenting with chronic breathlessness wait years for an explanatory diagnosis, leading to delays in accessing effective treatments and worse individual outcomes including premature mortality. In addition, delays to diagnosis are associated with increased healthc