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Background: During the COVID-19 pandemic, the majority of patients received ambulatory treatment, highlighting the importance of primary health care (PHC). However, there is limited knowledge regarding PHC workload in Europe during this period. The utilization of COVID-19 PHC indicators could facilitate the efficient monitoring and coordination of the pandemic response. The objective of this study
Over the last 50 years, there has been significant development of qualitative research and related methods in healthcare. Theoretical frameworks support researchers in selecting appropriate research approaches, procedures and analytical tools. However, the implications of the choice of theory are sparsely elucidated. Based on a text excerpt from a public debate article, the study aimed to show how
Bidirectional Low Temperature Networks (BLTNs) are an innovative technology of district heating and cooling systems. Because of their intrinsic feature of supplying simultaneous heating and cooling either directly from an energy source/sink or through distributed heat pumps and chillers, circulation pumps installed at each building extract water from the network and a distinct pressure cone is sub
Older adults have multiple medical and social care needs, requiring a shift toward an integrated person-centered model of care. Our objective was to describe and summarize Swedish experiences of integrated person-centered care by reviewing studies published between 2000 and 2023, and to identify the main challenges and scientific gaps through expert discussions. Seventy-three publications were ide
Alternative fuels, such as natural and bio-gas, are attractive options for reducing greenhouse gas emissions from combustion engines. However, the naturally occurring variation in gas composition poses a challenge and may significantly impact engine performance. The gas composition affects fundamental fuel properties such as flame propagation speed and heat release rate. Deviations from the gas co
Overuse of antibiotics is accelerating the antimicrobial resistance among pathogenic microbes which is a growing public health challenge at the global level. Higher resistance causes severe infections, high complications, longer stays at hospitals and even increased mortality rates. Antimicrobial resistance (AMR) has a significant impact on national economies and their health systems, as it affect
We have previously described a new series of selective and orally available galectin-1 inhibitors resulting in the thiazole-containing glycomimetic GB1490. Here, we show that the introduction of polar substituents to the thiazole ring results in galectin-1-specific compounds with low nM affinities. X-ray structural analysis of a new ligand-galectin-1 complex shows changes in the binding mode and l
Frontotemporal dementia (FTD) is the second most common cause of early-onset dementia after Alzheimer disease (AD). Efforts in the field mainly focus on familial forms of disease (fFTDs), while studies of the genetic etiology of sporadic FTD (sFTD) have been less common. In the current work, we analyzed 4,685 sFTD cases and 15,308 controls looking for common genetic determinants for sFTD. We found
Citizens have increasingly diversified their use of social media platforms, raising questions about which platforms are adopted and for what purposes. We use survey data from four countries (Canada, France, the United States, and the United Kingdom) gathered in 2019 and 2021 (n = 12,302) about Facebook, YouTube, Instagram, Twitter, Reddit, Snapchat, and WhatsApp. Political ideology predicts the ad
Identification of novel biomarkers for early diagnosis, prognosis, and treatment decision will be instrumental for improving disease outcome for patients suffering from complex diseases, such as cancer and autoimmune disorders. Within personalized medicine, the use of circulating biomarkers will allow clinicians to tailor medical treatment based on individual characteristics of each patient, using
Taking as the starting point the increasing interest for utilizing public procurement as a means to stimulate innovation, this paper explores some considerations for curriculum development for teaching public procurement of innovation. A basic understanding of what is a curriculum was used as a foundation for the development of a master level course in public procurement of innovation in a univers
In this paper, we propose a new methodology for optimal memory mapping of data and instructions to Scratch-Pad Memories (SPM). In the mapping process, we optimize, as the main priority, the number of memory accesses to minimize power consumption. Minimization of external memory accesses lowers switching activity and therefore power consumption. The optimization is done by finding Pareto-points, us
The Swedish HE Ordinance requires all supervisors of doctoral students to undergo introductory training. The content, goals, learning outcomes and duration is not specified by the Ordinance and thus practices vary between institutions. In 2009/2010, a new study program for doctoral supervisors was launched at Lund University. The program was designed to:- provide research-based support for doctora
The traditional sheet metal forming process, including cast steel die tool and conventional work materials, is fairly well established and analysed. Developments of new alternative materials make great demands upon new forming processes and manufacturing methods. A general goal for the manufacturing industries is to reduce the weight of metal parts, reduce batch sizes and reduce the lead-time of n
