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Accurate species identifications are the essential first step in understanding the medical, economic, and ecological importance of black flies. The utility of DNA barcoding based on cytochrome c oxidase subunit 1 (COI) sequences was evaluated for identifying six common species of Palearctic black flies in the subgenus Wilhelmia, including several that are virulent pests. Chromosomally identified l
Context/Objective: The variant rs13266634 in SLC30A8, encoding a beta-cell-specific zinc transporter, is associated with type 2 diabetes. We aimed to identify other variants in SLC30A8 that increase diabetes risk and impair beta-cell function, and test whether zinc intake modifies this risk. Design/Outcome: We sequenced exons in SLC30A8 in 380 Diabetes Prevention Program (DPP) participants and ide
Popular Abstract in Swedish För att förstå tillväxten av den kontinentala jordskorpan är det nödvändigt att kunna uppskatta balansen mellan juvenilt bidrag från manteln, infra-krustal omarbetning av jordskorpa och transport av krustalt material tillbaka till manteln. Sedan början av seklet har användandet av in situ U–Pb, Lu–Hf och O-isotop analyser av mineralet zirkon som ett verktyg för att adreTo understand the growth of continental crust, the balance between juvenile mantle derived extraction, infracrustal reworking and crustal recycling, needs to be estimated. Since the beginning of the century, the use of coupled in situ zircon U–Pb, Lu–Hf and O isotope analyses as a tool to address these questions have increased exponentially. Numerous compilations of ever growing datasets have been
What determines the seasonal and interannual variation of growth rates in trees in a tropical forest? We explore this question with a novel four-year high-temporal-resolution data set of carbon allocation from two forest plots in the Bolivian Amazon. The forests show strong seasonal variation in tree wood growth rates, which are largely explained by shifts in carbon allocation, and not by shifts i
Type 1 diabetes (T1D) is an autoimmune disease that results in the destruction of insulin producing pancreatic β-cells. One of the genes associated with T1D is TYK2, which encodes a Janus kinase with critical roles in type-Ι interferon (IFN-Ι) mediated intracellular signalling. To study the role of TYK2 in β-cell development and response to IFNα, we generated TYK2 knockout human iPSCs and directed
Women tend to have lower interest in engineering as compared to men, which previous research has shown is partly explained by gender differences in self-efficacy, social belongingness and communal career goals. Therefore, to attract more women to engineering, effective interventions are needed that target these factors. In this study, we evaluated an industry-designed intervention for high school
Over the past decade, our understanding of brain-waste clearance underwent a revolution after the discovery of the so-called glymphatic system. The glia-lymphatic (abbreviated, glymphatic) system was first described in 2012 as a paravascular macrosystem involved in the distribution of nutrients and clearance of metabolic waste from the brain parenchyma. The main actor of the system is the cerebros
We are developing techniques for studying the Rayleigh-Taylor (RT) and Richtmyer-Meshkov (RM) instabilities in a planar geometry at high-energy-densities at the National Ignition Facility (NIF). In particular, through the improvement of experimental imaging quality, we are progressing toward the study of the turbulent regime of the mixing regions in capsule implosion experiments for inertial confi
Abstract in TurkishHazreti Muhammed’in ailesi (Ehl-i Beyt), Şii mezhebi inancında merkezi bir konuma sahiptir. Bu dünyada şefaat edebilecek gayri maddi varlıklar olarak, Müslümanların hayatlarına tanık oldukları ve onlarla birlikte bulundukları söylenir. Ne yazık ki antropolojide, bu gibi gayri maddi ve insan-ötesi varlıklarla ilişkiler ihmal edilmektedir. Bu makale, insan-ötesi varlıkları sadece The Family of the Prophet Muhammad holds a central position in Shiʿi Muslim religiosity. As immaterial beings able to intercede in this world, they are said to be witnessing and co-present in the lives of Muslims. Anthropology has neglected relations with immaterial more-than-human beings like these. Instead of regarding them merely as symbols or moral exemplars, this essay focuses on the cultivat
Research shows that much of the blame for waste and lost resources can be traced to the design phase. The implementation of Circular Economy (CE) has the potential to reduce waste by encouraging reuse of resources in a closed loop. Given that designers are involved in the design process, this paper investigates whether they are properly equipped to take responsibility for the shift toward CE. A gr
Building materials account for a high percentage of the non-land cost of self-help housing. Few studies, however, have examined the use of building materials by self-help builders and the practicalities of producing and distributing the materials in an alternative manner. This paper discusses the nature of construction by self-help in the intermediate-sized Colombian city of Pereira, focusing in p
Thermal performance curves (TPCs) capture how population growth depends on temperature. When temperatures increase, such as during global change, TPCs may evolve to match new environmental temperatures. While previous studies mostly focus on population growth rate TPCs, evolution can also be strongly trait-dependent and require a multi-trait analysis. Here, we empirically tested how TPCs and multi
Drawing on fine-grained ethnographies from Bissau, Chile, China, Egypt, Ecuador and Nepal, this volume explores how politically, religiously and (sub-)culturally inspired Utopias motivate youth in the Global South to imagine, enact and embody what was missing in the past and present. As a fluid age cohort and a social category between childhood and adulthood – and hence with tenuous links to the s
Streptococcus pneumoniae resists host defenses through multiple surface factors, yet their specific contribution to protection against antimicrobial peptides remains incompletely understood. We examined the role of pneumococcal surface protein A (PspA) and the polysaccharide capsule in protection against the human defensin HNP-1. PspA conferred increased resistance to HNP-1-induced killing, show
Soft power and public diplomacy compose the new reality shaping the dynamics of contemporary international relations. Strategic narratives represent an essential means for political actors to extend their influence, gain the public opinion’s support for their actions and fulfill their foreign policy goals. The thesis focused on the Chinese Party state’s construction of strategic narratives targete
