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Parkinson's disease (PD) is characterized by rigidity, akinesia, postural instability and tremor. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) reduces tremor but the effects on postural instability are inconsistent. Another component of postural control is the postural strategy, traditionally referred to as the ankle or hip strategy, which is determined by the coupling between the
Background: The characteristics of Parkinson's disease (PD) include postural instability and resting tremor. However, reductions of tremor amplitude do not always improve postural stability. Research question: What is the effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) on spectral analysis of body movement in patients with PD when tested without anti-PD medication? The effe
Taxes and subsidies on foods and nutrients have the potential to promote healthier diets and thereby reduce mortality. In this study, we examine the effects of such policy instruments on Swedish public health. Specifically, we estimate the effects of food and nutrient taxes and subsidies on mortality averted and postponed in Sweden, using both demand system estimations and simulation models. We ev
Here we discuss the current state of knowledge of terrestrial planet formation from the aspects of different planet formation models and isotopic data from 182Hf-182W, U-Pb, lithophile-siderophile elements, 48Ca/44Ca isotope samples from planetary building blocks, recent reproduction attempts from 36Ar/38Ar, 20Ne/22Ne, 36Ar/22Ne isotope ratios in Venus’ and Earth’s atmospheres, the expected solar
BACKGROUND: Tremor is a cardinal symptom of Parkinson's disease (PD) that may cause severe disability. As such, objective methods to determine the exact characteristics of the tremor may improve the evaluation of therapy. This methodology study aims to validate the utility of two objective technical methods of recording Parkinsonian tremor and evaluate their ability to determine the effects of Dee
Purpose: In early 2000s Six Sigma and Lean were combined into Lean Six Sigma (LSS), which has been one of the major strategic quality initiatives all over the world. Now, we are in the era of the 4th Industrial Revolution (IR), which changes almost everything including LSS and quality management (QM) in the companies. We need new paradigm of LSS to boost LSS activities in this 4th IR era. In this
The standard approach to the evaluation of tremor in medical practice is subjective scoring. The objective of this study was to show that signal processing of physiological data, that are known to be altered by tremor in Parkinson's disease (PD), can quantify the postural dynamics and the effects of DBS. We measured postural control and its capacity to adapt to balance perturbations with a force p
Background: Management of schizophrenia is sub-optimal in many patients. Targeting negative symptoms, among the most debilitating aspects of schizophrenia, together with positive symptoms, can result in significant functional benefits and dramatically improve quality of life for patients and their carers. Cariprazine, a partial agonist of the dopamine receptors D2/D3 has demonstrated effectiveness
Assessment of bilingual children in only one language fails to acknowledge their distributed linguistic competence and has been shown to overidentify language disorder in bilingual populations. However, other factors, sometimes associated with bilingualism, may also contribute to low results in language assessments. Our aim was to examine the impact of these factors on language abilities. We used
Autoimmunity associated with tumor cell development seems an important mechanism by which to prevent progression to clinical cancer. In this brief review, tumor autoantigens associated with paraneoplastic syndrome, non-HLA- associated organ-specific autoimmune diseases, and the highly cell-specific autoimmune eradication of the islet beta cells in type I diabetes are compared and discussed. It is
We investigate the enrichment patterns of several delivery scenarios of the volatiles to the atmospheres of ice giants, having in mind that the only well constrained determination made remotely, namely the carbon abundance measurement, suggests that their envelopes possess highly supersolar metallicities, i.e., close to two orders of magnitude above that of the protosolar nebula. In the framework
This dissertation investigates the relation between aesthetics and politics by interpreting three experimental novels by Virginia Woolf, Djuna Barnes and Gertrude Stein. By theorizing the relation between language, subject, voice and ideology it questions the autonomous subject as a ground for political action and criticality. This is done by challenging language as a vehicle for individual expres
Oxidative degradation is a serious threat to long-term use and recyclability of polymers. Successful recycling of polymeric quality products requires characterization of the polymer material after reprocessing and use. Lately, a growing awareness of the heterogeneous nature of degradation has developed in terms of physical spreading, non-uniform distribution of stabilizer, physical loss of stabili
The reaction between galena powder and ethylxanthate ions has been studied in aqueous solution. Qualitative analysis of the compounds present on the galena surfaces before and after treatment with potassium ethylxanthate has been performed by means of diffuse reflectance infrared Fourier transform (DRIFT) spectroscopy. Atomic absorption spectrophotometry has been used to determine the total lead c
This book has come out of the work of the European ‘ATHENA’ Thematic Network, which is a network of higher education institutions involved in feminist research and in delivering Women’s Studies and Gender Studies programmes. Women’s Studies have developed a particular pedagogic focus that values both recognition of the ‘personal’ and critical reflective thinking in learning communities. Feminist
With the exponential growth of the World Wide Web, automated subject classification of Web pages has become a major research issue in information and computer sciences. Organizing Web pages into a hierarchical structure for subject browsing is gaining more recognition as an important tool in information-seeking processes. In this thesis, different automated classification approaches, focusing on
The effect of various deposition techniques, electrode materials and posttreatment with tetrabutylammonium and tetrabutylphosphonium salts on the electrochemical behavior and stability of various Prussian blue (PB) modified electrodes, namely PB modified glassy carbon electrodes, silicate-film supported PB modified glassy carbon electrodes, PB-doped silicate glassy carbon electrodes, PB modified c
Popular Abstract in Swedish Denna avhandling utgör den första delen i en planerad serie på tre rapporter med utgångspunkt i data insamlade läsåret 1993/94 i årskurs 9 vid en grundskola, där det lokala skolprojektet Tonåringens livssituation och livstolkning genomförts i ämnet religionskunskap. Det övergripande syftet med studien är att undersöka vilka centrala livsvärden eleverna ger uttryck för iThis dissertation makes up the first report based on data collected during the project "Teenagers: aspects of their life style and attitudes" (Tonåringens livssituation och livstolkning) in the subject Religious Studies taken by pupils attending Year 9 during the 1993/94 school year. The general aim of the study is to discover the central values of life which pupils hold, as expressed in an essay
This study is ultimately concerned with the attainment of stable peace in international affairs. The notion of stable peace-understood as military conflict resolution being unthinkable, no matter the severity of a conflict-rivals traditional accounts of the logic of international relations. Confidence-certainty as to the intentions of another actor-are at the heart of stable peace relationships. I
OBJECTIVE: To use self-reported disability (Roland-Morris Disability Questionnaire [RMDQ]) to assess the criterion validity of straight leg raising (SLR) test and flexion range of motion (ROM) (fingertip-to-floor test) before and after stratification by sex and presence/absence of radicular pain. DESIGN: Cross-sectional study. SETTING: Outpatient physical therapy clinic. PARTICIPANTS: Subjects wit
