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The enzyme dUTPase catalyses the hydrolysis of dUTP to dUMP and pyrophosphate, thereby suppressing incorporation of uracil into DNA and providing a pool of dUMP, the precursor of dTTP. Hydrolysis of other nucleotides similar in structure to dUTP would conceivably be physiologically detrimental and high specificity of the reaction seems to be necessary. In this work, we characterize the substrate s

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Twenty-six patients were operated because of osteo-arthritis of the trapeziometacarpal joint. After excision of the trapezium, they were randomized to receive either a Swanson silicone trapezium implant or a tendon interposition arthroplasty using a strip of the abductor pollicis longus tendon (APL). No infection or clinical silicone synovitis occurred and no major radiographic cyst formation was

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A lectotype for Hieracium diaphanum Fr. (1819) is designated and it is compared with similar species from southern Sweden, i.e. H. pseudodiaphanum (Dahlst.) Johanss., H. jonsbergense T. Tyler, H. hemidiaphanum (Dahlst.) Brenner, H. dalicum Johanss. and H. subglaucovirens Zahn ex Johanss. & Sam. It is concluded that the name H. diaphanum (s. stricto) does belong to a very rare species hitherto

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The effects of non-stoichiometry and isomorphic substitutions on the properties of some apatite-type compounds were investigated. These investigations were performed both in the fields of Portland cement chemistry and apatitic calcium phosphate-based biocements. Apatite compounds were synthesized by solid state methods and by hydrolysis of the reactant α-tricalcium phosphate (α-TCP). The materials

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Popular Abstract in Swedish Gel-dosmätningar för kontroll av strålbehandling av cancertumörer När en patient strålbehandlas avser man att bestråla sjuka områden i kroppen. Det är dock omöjligt att göra detta utan att därmed även till viss del stråla på omkringliggande organ och komplikationer kan då uppstå. För att minimera dessa bieffekter och optimera behandlingen används ofta en så kallad dospGel dosimetry was used together with magnetic resonance imaging (MRI) to measure three-dimensional absorbed dose distributions in radiation therapy. Two different dosimeters were studied: ferrous- and monomer gel, based on the principles of radiation-induced oxidation and polymerisation, respectively. Single clinical electron and photon beams were evaluated and gel dose distributions were mainly w

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The article investigates translation culture in the Swedish dominion Swedish Pomerania during the eighteenth century, with a particular focus on periodicals.

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The purpose of the study was to evaluate patient relevant outcome after total hip replacement (THR) in patients with primary osteoarthritis (OA). 247 patients >50 years of age with primary hip OA, operated on with THR (Sept1995—Oct1998), were investigated consecutively and prospectively. 68 of the THR were made with hybrid technique. A preoperative radiographic classification was made. Evaluation

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Popular Abstract in Swedish Denna avhandling skall främst ses som ett bidrag till diskussionen om en framväxande ny "kulturaliserad" ekonomi. Avhandlingens syfte är att genom att analysera produktion och konsumtion av mejerivaror följa hur en ny ekonomi formas och tar plats i vardagen samt se vilka kulturella värderingar och föreställningar som skapas i denna process. Den teroetiska inspirationen This dissertation is to be regarded as a contribution to the discussion about a "cultural economy". The aim of the study is to gain a perspective as to how a new economy can be shaped and take its place in everyday life, as well as identify the cultural values and ideas created in the process, by analysing the production and consumption of dairy products. Theoretical inspiration is derived from st

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Popular Abstract in Swedish I stort sett alla finrötter hos gran och många andra trädslag är koloniserade av ektomykorrhizasvampar (EM-svampar). Dessa lever i symbios med granen och utbyter mineralnäringsämnen mot sockerarter, som värdträdet bildat i fotosyntesen. EM-svamparna har visats överföra kalcium, kalium, kväve, magnesium och fosfor till sina värdträd. Den svenska skogen ingår i det boreaA method based on ingrowth mesh bags was developed to study the production of EMM. These bags were made of nylon mesh with a mesh size of 50 mu-m, which allows colonisation by fungal mycelia but excludes the tree roots. Using this method, the production of EMM was estimated in forest stands subjected to whole-tree harvesting (WTH) and in forest stands with different nutrient status regarding potas

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Rate-ratio asymptotic analysis is carried out to elucidate the influence of hydrogen on the structure and critical conditions for extinction of nonpremixed methane flames. Steady, axisymmetric, laminar flow of two counterflowing streams toward a stagnation plane is considered. One stream, called the fuel stream is made up of a mixture of methane (CH4) and nitrogen (N-2). The other stream, called t

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The clitoris contributes to the normal female sexual response cycle. A significance of cyclic guanosine monophosphate (GMP) has been assumed in the control of clitoral vascular smooth muscle. As only a few investigations on the physiology of the vascular and non-vascular clitoral tissue have been carried out, knowledge on the mechanisms controlling this particular female genital organ is still vag

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Inferior olivary cells projecting as climbing fibres to the forelimb area of the cerebellar C3 zone were investigated with respect to their cutaneous and muscle afferent input in barbiturate-anaesthetized cats. Climbing fibre responses were recorded from single cerebellar cortical Purkinje cells on natural stimulation of the skin and on electrical stimulation of nerves to m. biceps brachii, m. tri

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The inlet geometry of the combustion chamber of a Helmholtz type pulse combustor was changed by altering the position of a stagnation plate, or flame holder, near the inlet. Three different flame fielder positions were studied. The operating characteristics in terms of time resolved pressure and heat release, time averaged tail pipe temperature and concentrations of O2 and NOx in the outlet decoup

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Changes in soil microbial community structure and development of metal tolerance as a result of past applications of unamended sewage sludge and metal-amended sewage sludge were found in soils of a long-term field experiment at Braunschweig, Germany. Both the rate of sewage sludge application and metal amendment affected the size and activity of the microbial biomass and had caused changes in micr