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The skin provides an attractive alternative to the conventional drug administration routes. Still, it comes with challenges as the upper layer of the skin, the stratum corneum (SC), provides an efficient barrier against permeation of most compounds. One way to overcome the skin barrier is to apply chemical permeation enhancers, which can modify the SC structure. In this paper, we investigated the

This research report was prepared in the framework of the EU-funded project “Central Asian Law: Legal Cultures and Business Environments in Central Asia” (project number 870647 H2020 MSCA-RISE 2019-2023), which runs from 01/03/2020 through 28/02/2024. The project is coordinated by Lund University, and the project consortium includes European universities (University of Zurich, Charles University P

Supply chain visibility is a concept that is gaining increasing attention. Increasing levels of visibility in the supply chain is considered beneficial in many respects. A systematic literature review identified 47 empirical research papers from international scientific journals. Two main findings emerged from the content analysis. First, the perspectives provided in the extant literature can be g

This commentary elaborates on different methodological aspects complicating the interpretation of epidemiological data related to the current COVID-19 pandemic, thus preventing reliable within and across-country estimates. Firstly, an inaccuracy of epidemiological data maybe arguably be attributed to passive surveillance, a relatively long incubation period during which infected individuals can st

We use a case of intact cord resuscitation to argue for the beneficial effects of an enhanced blood volume from placental transfusion for newborns needing resuscitation. We propose that intact cord resuscitation supports the process of physiologic neonatal transition, especially for many of those newborns appearing moribund. Transfer of the residual blood in the placenta provides the neonate with

The book identifies the key analytical issues that need to be considered in determining whether a State is responsible under the ECHR for omissions. The focal question is whether and how omissions by the State can be conceptualised into failures to fulfil positive obligations. In addition to this technical analytical question, the book also reflects upon what is at stake for the political communit

This paper analyses the inherent competence conflict between the economic and the monetary policies under EU law. The particular policy areas have come under scrutiny with regards to the financial rescue packages issued in the course of the financial crisis (PSPP) as well as the Covid-19 pandemic (PEPP). Both crises have exposed some of the Union’s core morbidities: a lack of competence at EU leve

The structures of two fungal norsesquiterpenes containing a diepoxide functionality, isolated from cultures of the basidiomycete Resupinatus leightonii, were elucidated by a combination of X-ray analysis, NMR spectroscopy and molecular mechanics calculations.

First-generation migrants tend to have better health than those of native ancestry, while second-generation migrants often are affected by negative health assimilation. Less is known about immigrants arriving before their teens, the 1.5 generation, or those with one native and one immigrant parent, the 2.5 generation. We apply logistic regression models to study physical and mental health outcomes

This paper contributes to the literature on long-term changes in intergenerational persistence of equality of opportunity. Social origin is measured comprehensively both as social class background, and estate-based surname status origin – both from mothers and fathers. The paper aims to link an expanding literature on surname mobility to the conventional field of intergenerational mobility researc

Hizbullah, or the Islamic Resistance in Lebanon, is considered a key actor in Lebanon and theMiddle East. Its importance is often attributed to its commitment to an armed struggle against Israel, its ties with the Islamic Republic in Iran and, more recently, to its military engagementin regional conflicts. Much less attention is given to the relationship between Hizbullah and its constituents in L

As global migration alters the demography of Swedish cities in the postwelfare era, socio-spatial polarisation and discrimination present acute challenges. In recent decades, Malmö has transformed from an industrial into a postindustrial, service economy-oriented city. The neoliberal urban planning and regeneration policies guiding such processes carry detrimental social and economic effects for u

Synthesis of diketopiperazines has been of long-standing interest in both natural product synthesis and medicinal chemistry. Here, we present an operationally convenient and efficient approach to the fused indoline-diketopiperazine tricyclic core of glionitrin A/B and related structures using a Pd-catalyzed C-H activation reaction to form the indoline five-membered ring. Exploratory work aimed at

Cancer research has transformed our view on cellular mechanisms for oxygen sensing. It has been documented that these mechanisms are important for maintaining animal tissues and life in environments where oxygen (O2) concentrations fluctuate. In adult animals, oxygen sensing is governed by the Hypoxia Inducible Factors (HIFs) that are stabilized at low oxygen concentrations (hypoxia). However, the

BACKGROUND: Individuals are exposed to air pollution and ionizing radiation from natural sources through inhalation of particles. This study investigates the association between cardiac arrhythmias and short-term exposures to fine particulate matter (particulate matter ≤2.5 µm aerodynamic diameter; PM2.5) and particle radioactivity.METHODS: Ventricular arrhythmic events were identified among 176 p

This article analyses how Sweden has adapted to the worsened security situation in its vicinity following Russia’s illegal annexation of Crimea and war in Eastern Ukraine. The paper builds on security policy research focused on neoclassic realism and small state strategies in order to explore how the, broadly unknown, security policy from 2009 has been implemented in practice since 2014, through w

The study investigates the development of defmiteness in two groups of Russian-speaking learners of Swedish, one beginner group and one more advanced group. While Russian does not have articles, Swedish expresses defmiteness through a complex noun-phrase (NP) structure. Using an oral elicitation task, the study examines the learners' ability to produce morphemes that encode (in)defmiteness, their