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Popular Abstract in Swedish En magnetkamera kan med hjälp av diffusionsviktad bildtagning användas för att avbilda hjärnans nervsystem. Denna teknik kan utnyttjas för studier av hur hjärnans delar är sammankopplade, men även för att indirekt mäta egenskaper hos hjärnans mikrostruktur. Detta avhandlingsarbete vidareutvecklar de biofysikaliska modeller och mätmetoder som används för denna indirekta Diffusion MRI is widely used to study brain structure in vivo. While this technique is often applied to investigations of brain connectivity, it can also be used to infer specific information about the tissue microstructure; for example, to estimate the axon diameter. In the present work, the role of tissue microstructure and water exchange in biophysical models employed in diffusion MRI was inves

Popular Abstract in Swedish I cellen styrs allt av biomolekylernas förmåga till igenkänning och växelverkan med varandra. Molekylernas speciella egenskaper bygger upp kroppens alla komplicerade funktioner, till exempel immunförsvar, celldelning och muskelarbete. Interaktionerna mellan biomolekylerna kan vara av olika karaktär; de beskrivs som starka eller svaga (affinitet), långsamma eller snabba Molecular recognition and interaction is fundamental for the function of biological systems. The properties of the interacting biomolecules dictate the type of forces involved and the strength and dynamics of the interaction. Many interactions are very strong whereas others exhibit weak affinity. Typically, weak interactions work in concert to trigger a biological response. The advantage with thi

Higher plants and algae use oxygenic photosynthesis to convert solar energy to reducing equivalents and chemical energy. The ultimate electron donor to oxygenic photosynthesis is water. Oxidation of water to oxygen occurs in the oxygen-evolving complex (OEC) in Photosystem II (PSII). The OEC is composed of four Mn atoms, Ca2+ and Cl-. The OEC cycles through five states (S0 - S4) during oxidation o

Popular Abstract in Swedish Njurens funktion är avgörande för att reglera extracellulärvätskans volym och sammansättning. Varje människonjure består av ca en miljon nefron, vilka utgör den minsta funktionella enheten. Via den afferenta arteriolen når blodet ett kapillärnät i nefronet. På grund av ett högt tryck i kapillärnätet filtreras vätska ut och samlas upp i en rund struktur, Bowman´s kapsel,Studies were performed to investigate the influence of the vasoconstrictors angiotensin II (AII) and norepinephrine (NE) on calcium metabolism in smooth muscle cells of afferent arterioles. Fura-2 and image analysis techniques were used to evaluate calcium responses in the proximal and distal parts of afferent arterioles with attached glomeruli. AII and NE increase intracellular calcium concentrat

Popular Abstract in Swedish Omkring hälften av alla kvinnor kommer någon gång efter 50 års ålder att drabbas av ett benbrott. Ett benbrott ger upphov till smärta, en risk för långvarig invaliditet och förtida död. Det är viktigt att försöka hitta dem som riskerar att drabbas, eftersom det möjliggör förebyggande behandling. Hur stor risken är att man drabbas av ett benbrott på äldre dagar beror fraApproximately half of all women will sustain a fracture after the age of 50. Fractures may cause long-term disability and excess mortality. Identifying individuals at high risk of sustaining a fracture is important in the development of primary and secondary prevention strategies. In this study, initiated to identify factors associated with a high risk of future fractures, 1 044 women, all 75 yea

The period from 1910 to 1930 was a time when a number of theoretical systems saw the light of the day in Central Europe: psychoanalysis, neopositivism, phenomenology, the Warsaw School of logic, Gestalt-psychology and the structuralism of the Prague School of Linguistics. The Prague School arose in the liberal-minded Prague of the 1920s and came to have an enormous influence on multiple fields wit

In making capacity estimates and cost calculations in the manufacturing industry, many products and production systems are often involved, making the data in their totality difficult to grasp. Introducing the concept of the characteristic part, which is a fabricated part seen as representative of all parts produced in terms of demand, setup time, cycle time, average batch size and total number of

Recently, Burger et al. (2011) developed a new 1-D SST model which allows for more realistic predictions of the sludge settling behaviour than traditional 1-D models used to date. However, the addition of a compression function in this new 1-D model complicates the model calibration. This study aims to report advances in the calibration of this novel 1-D model. Data of the evolution of the sludge

A priori calculations of phonon broadening of core levels in metals are presented. The effects of nonlinear screening and higher-order couplings are taken into account for the first time. The nonlinear screening effects are very important for Li and must be accounted for in order to obtain agreement with experiment.

This paper discusses whether the Western democracy promotion project of exporting civil society to the Balkans is a form of colonialism. In particular, it deals with they system of project life, and project culture which has structured Western development interventions. Examples come from the author's own work as consultant in Bosnia, Albania and Romania in the field of civil society/NGO developme