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Immunity to Rotavirus infection across ages

Rotavirus (RV) is a double-stranded RNA virus that mainly affects young children under the age of five years. It is one of the leading causes of dehydrating gastroenteritis. Every year, about 200,000 child deaths occur due to RVinfection. Vaccines exist and are in use worldwide. However, these vaccines' efficacy is relatively low in countries where deaths due to the virus are high.The aim of the w

Predicting the survival of patients with peritoneal carcinomatosis of colorectal origin treated by aggressive cytoreduction and hyperthermic intraperitoneal chemotherapy

BACKGROUND: Peritoneal carcinomatosis in the absence of distant metastasis occurs in approximately 8 per cent of patients with colorectal cancer. Cytoreduction followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a new treatment option. Patient selection is crucial to outcome.METHODS: Cytoreduction followed by HIPEC was performed in 102 patients with peritoneal carcinomatosis. The foll

IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage

Conventional dendritic cells (cDCs) consist of two major functionally and phenotypically distinct subsets, cDC1 and cDC2, whose development is dependent on distinct sets of transcription factors. Interferon regulatory factor 8 (IRF8) is required at multiple stages of cDC1 development, but its role in committed cDC1 remains unclear. Here, we used Xcr1-cre to delete Irf8 in committed cDC1 and demons

Impact of amoxicillin therapy on resistance selection in patients with community-acquired lower respiratory tract infections : A randomized, placebo-controlled study

Objectives: To determine the effect of amoxicillin treatment on resistance selection in patients with community-acquired lower respiratory tract infections in a randomized, placebo-controlled trial. Methods: Patients were prescribed amoxicillin 1 g, three times daily (n = 52) or placebo (n = 50) for 7 days. Oropharyngeal swabs obtained before, within 48 h post-treatment and at 28-35 days were asse

A prospective cohort study identifying radiologic and tumor related factors of importance for breast conserving surgery after neoadjuvant chemotherapy

Introduction: Neoadjuvant chemotherapy (NAC) is an established treatment option for early breast cancer, potentially downstaging the tumor and increasing the eligibility for breast-conserving surgery (BCS). The primary aim of this study was to assess the rate of BCS after NAC, and the secondary aim was to identify predictors of application of BCS after NAC. Materials and methods: This was an obser

IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies

The important bacterial pathogen Streptococcus pyogenes secretes IdeS (immunoglobulin G-degrading enzyme of S. pyogenes), a proteinase that cleaves human immunoglobulin G (IgG) antibodies in the hinge region resulting in Fc (fragment crystallizable) and F(ab')2 (fragment antigen-binding) fragments and protects the bacteria against phagocytic killing. Experiments with radiolabeled IdeS and flow cyt

Label-FreeHigh-ResolutionPhotothermalOpticalInfraredSpectroscopyfor Spatiotemporal Chemica lAnalysis in Fresh, Hydrated Living Tissues and Embryos

Label-free chemical imaging of living and functioning systems is the holy grail of biochemical research. However, existing techniques often require extensive sample preparation to remove interfering molecules such as water, rendering many molecular imaging techniques unsuitable for in situ structural studies. Here, we examined freshly extracted tissue biopsies and living small vertebrates at submi

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

CD40-stimulating immunotherapy can elicit potent anti-tumor responses by activating dendritic cells and enhancing T-cell priming. Tumor vessels orchestrate T-cell recruitment during immune response, but the effect of CD40-stimulating immunotherapy on tumor endothelial cells has not been evaluated. Here, we have investigated how tumor endothelial cells transcriptionally respond to CD40-stimulating

A recurring dominant negative mutation causes autosomal dominant growth hormone deficiency--a clinical research center study

Familial isolated GH deficiency type II (IGHD-II) is an autosomal dominant disorder that has been previously shown in some patients to be caused by heterogeneous GH gene defects that affect GH messenger RNA (mRNA) splicing. We report here our finding of multiple G-->A transitions of the first base of the donor splice site of IVS 3 (+ 1G-->A) in IGHD II subjects from three nonrelated kindreds from

Profiling the nasopharyngeal Microbiome in patients with community-acquired pneumonia caused by Streptococcus pneumoniae : diagnostic challenges and ecological insights

Community-acquired pneumonia (CAP) is a significant health threat for adults. Although conjugate vaccines have reduced pneumococcal CAP incidence in children, Streptococcus pneumoniae-related CAP remains prevalent among older adults. The nasopharynx acts as a reservoir for S. pneumoniae, yet the interplay between this pathogen and the nasopharyngeal microbiome during and after pneumonia remains po

Polarization position angle standard stars : a reassessment of θ and its variability for seventeen stars based on a decade of observations

Observations of polarization position angle (θ) standards made from 2014 to 2023 with the High Precision Polarimetric Instrument (HIPPI) and other HIPPI-class polarimeters in both hemispheres are used to investigate their variability. Multiband data were first used to thoroughly recalibrate the instrument performance by bench-marking against carefully selected literature data. A novel co-ordinate

Grounding Embodied Multimodal Interaction : Towards Behaviourally Established Semantic Foundations for Human-Centered AI : The 1st International Workshop on Knowledge Representation for Hybrid Intelligence (KR4HI 2022), part of International Conference on Hybrid Human-Artificial Intelligence (HHAI 2022), Amsterdam, The Netherlands, June 13-17, 2022

We position recent and emerging research in cognitive vision and perception addressing three key questions: (1) What kind of relational abstraction mechanisms are needed to perform (explainable) grounded inference --e.g., question-answering, qualitative generalisation, hypothetical reasoning-- relevant to embodied multimodal interaction? (2) How can such abstraction mechanisms be founded on behavi

Netquant2 : automated web-based quantification of neutrophil extracellular traps from fluorescence microscopy

Neutrophil extracellular traps (NETs) are structures that neutrophils form in response to various stimuli, including invading pathogens. NETs are increasingly studied, and their importance has been demonstrated in autoimmunity and infection. However, no consensus has emerged on their quantification, with many studies resorting to manually counting NETs in microscopy images. NETQUANT is a free soft

Residual Stroke Risk Among Patients With Atrial Fibrillation Prescribed Oral Anticoagulants : A Patient-Level Meta-Analysis From COMBINE AF

BACKGROUND: Despite oral anticoagulation, patients with atrial fibrillation (AF) remain at risk of ischemic stroke and systemic embolism (SE) events. For patients whose residual risk is sufficiently high, additional therapies might be useful to mitigate stroke risk. METHODS AND RESULTS: Individual patient data from 5 landmark trials testing oral anticoagulation in AF were pooled in A Collaboration

Kalix Bridge Digital Twin—Structural Loads from Future Extreme Climate Events

Environmental loads, such as wind and river flow, play an essential role in the structural design and structural assessment of long-span bridges. Climate change and extreme climatic events are threats to the reliability and safety of the transport network. This has led to a growing demand for digital twin models to investigate the resilience of bridges under extreme climate conditions. Kalix bridg

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THE DECODING CHINA DICTIONARY EDITED BY MALIN OUD AND KATJA DRINHAUSEN The Decoding China Dictionary Edited by Malin Oud and Katja Drinhausen With contributions by David Bandurski, Katja Drinhausen, Jerker Hellström, Malin Oud and Marina Rudyak Design concept and typesetting by Tommaso Facchin Illustrations by Anna Formilan Layout by Eve Rogers Contact Malin Oud malin.oud@decodingchina.eu Copyrigh

https://rwi.lu.se/wp-content/uploads/2021/03/Decoding-China-Publication_FINAL.pdf - 2025-11-17

Uppsatsriktlinjer

Uppsatsriktlinjer Historiska institutionen Riktlinjer för uppsatsarbete på kandidatkursen Uppdaterad HT 2020 - 2 - Innehåll ALLMÄNNA RIKTLINJER .................................................................................................. 3 UPPSATSKURSENS FUNKTION OCH MÅL ................................................................................... 3 ATT SKRIVA OCH VENTILERA EN KANDIDATU

https://www.hist.lu.se/fileadmin/user_upload/historiska/hist/Historia/dokument_utb_Hist/UppsatsriktlinjerKandidat.pdf - 2025-11-17

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LuNns UNIVERSITET Husstyrelsen för SOL-husen HUMANISTISKA OCH TEOLOGISKA FAKULTETERNA PROTOKOLL 2019-09-03 kl 13:15-15:00 HTDR KOM HTS HT-biblioteken SOL Sektion 3 SOL Driftsenhet HT, ordförande sekreterare huvudsþddsombud ekonom husintendent ekonomichef Sektion 4 SOL Kansli HT 1(4) tom$ 100 Närvarande ledamöter Övriga Frånvarande ledamöter Sandra Cronhamn Mia-Marie Hammarlin Marina Hansson Viktor

https://www.ht.lu.se/fileadmin/user_upload/driftsenhet_ht/SOL-husen_intranaet/protokoll_SOL-husen_190903__justerat.pdf - 2025-11-17

Protokoll

Protokoll Besöksadress LUX, Lunds universitet, Helgonavägen 3, Lund, Postadress Box 192, 221 00 Lund Telefon 046-222 95 89, Fax 046-222 32 28 E-post Martin.Lembke@ctr.lu.se, Internet http://www.teol.lu.se/person/MartinLembke Husstyrelsen LUX Närvarande ledamöter Lotta Flink HTS Viktoria Hörnlund HT-biblioteken Martin Jönsson Filosofiska institutionen Gabriella Nilsson Institutionen för kulturveten

https://www.ht.lu.se/fileadmin/user_upload/driftsenhet_ht/LUX_intranaet/Protokoll_husstyrelsen_LUX_2023-05-09.pdf - 2025-11-17

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BOOK OF ABSTRACTS 25-27 September 2014 · CCS · Lund University The First Conference of the International Association for Cognitive Semiotics © Line Brandt http://konferens.ht.lu.se/en/iacs-2014 IACS-2014 1 Book of Abstracts The First Conference of the International Association for Cognitive Semiotics (IACS-2014) September 25-27, 2014 Lund University 2 Cover art by Line Brandt Copyright © Local Org

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/IACS_Book_of_Abstracts-6.pdf - 2025-11-17