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Photoprotection in a purple phototrophic bacterium mediated by oxygen-dependent alteration of carotenoid excited-state properties

Carotenoids are known to offer protection against the potentially damaging combination of light and oxygen encountered by purple phototrophic bacteria, but the efficiency of such protection depends on the type of carotenoid. Rhodobacter sphaeroides synthesizes spheroidene as the main carotenoid under anaerobic conditions whereas, in the presence of oxygen, the enzyme spheroidene monooxygenase cata

Electrochemical Investigation of Nickel Pattern Electrodes in H-2/H2O and CO/CO2 Atmospheres

In this study, nickel pattern electrodes were electrochemically investigated in a three-electrode setup, operating both with H-2/H2O and CO/CO2 atmospheres. Heating introduced structural differences in the nickel layer among the pattern electrodes, which appear to affect the electrode performance. Both dense and porous nickel pattern electrodes were formed by heating. Holes appeared in the nickel

Late Ordovician-Early Silurian delta C-13 chemostratigraphy in the Upper Mississippi Valley: implications for chronostratigraphy and depositional interpretations

A pioneer study of the previously unknown delta C-13 chemostratigraphy in the Ordovician/Silurian boundary interval in eastern Iowa and northeastern Illinois resulted in the discovery of the Hirnantian Isotope Carbon Excursion (HICE). The presence of this major isotope excursion in the Mosalem Formation in Iowa and the Wilhelmi Formation in Illinois, which indicates that the excursion interval in

Mortality results from the Goteborg randomised population-based prostate-cancer screening trial

Background Prostate cancer is one of the leading causes of death from malignant disease among men in the developed world. One strategy to decrease the risk of death from this disease is screening with prostate-specific antigen (PSA); however, the extent of benefit and harm with such screening is under continuous debate. Methods In December, 1994, 20 000 men born between 1930 and 1944, randomly sam

The Phantasmatic in romantic subjective experience and aesthetics

The goal of this research is to asses the reach and characteristics of the Phantasmatic as a proposed concept, useful to understand fundamental aspects of the romantic subjective experience in artists, aesthetes and writers. This experiential level has been exemplified in artists that had been living or intermittently residing in Dresden during the first half of 19th century. Caspar David Friedric

European Union's Gas Supply Issue. To Securitize or not to Securitize?

This study examines the European Union (EU) gas supplies, particularly those coming from the Russian Federation. The increasing EU dependency upon Russian gas and recent gas disruptions make European leaders think about securitizing gas supplies issue. The aim of the thesis is to analyse consequences of securitization of the gas supplies in the EU through scrutinizing Russian foreign policy in th

Climate change, relocation and the distribution of responsibility : in search for Kiribati's strongest connection

This essay addresses the needs of so called ‘climate migrants’. It focuses exclusively on the relocation of the population of Kiribati, a small island nation in the Pacific Ocean whose very existence is threatened by the effects of climate change. With the principles of causality, morality, capacity and community, Miller’s Connection Theory provides the study with a framework for discussing the di

Yersinia pestis Ail recruitment of C4b-binding protein leads to factor I- mediated inactivation of covalently and noncovalently bound C4b

The outer membrane protein Ail of Yersinia pestis mediates several virulence functions, including serum resistance. Here, we demonstrate that Ail binds C4b-binding protein (C4BP), the primary fluid-phase regulator of the classical and lectin pathways. Non-covalent binding of C4 and C4b to Ail was also observed. C4BP bound to Ail can act as a cofactor to the serine protease factor I (fI) in the cle

Muscle mass and plasma myostatin after exercise training : a substudy of Renal Exercise (RENEXC)-a randomized controlled trial

BACKGROUND: Sarcopenia increases as renal function declines and is associated with higher morbidity and mortality. Myostatin is a negative regulator of muscle growth. Its expression in response to exercise is unclear. In this prespecified substudy of the Renal Exercise (RENEXC) trial, we investigated the effects of 12 months of exercise training on sarcopenia, muscle mass and plasma myostatin and

Implementation framework for bim-based risk management

There is currently an imbalance with regards to the way that risks are treated in construction projects. Risks associated with structural failures as well as construction safety risks are often in focus while building performance risks (e.g. related to moisture or energy performance) receive less attention. These types of risks often disproportionately affect the end users/owners and can in many c

Non-small cell lung cancer cells produce a functional set of complement factor I and its soluble cofactors

The complement system is important for protection from invading pathogens, removal of waste products and guidance of the immune response. Furthermore, complement can be also targeted to cancer cells. However, membrane-bound inhibitors over-expressed by certain types of tumor cells restrict the cytotoxic activity of complement. Herein we report that non-small cell lung cancer (NSCLC) cells produce

Membrane protein identification: N-terminal labeling of nontryptic membrane protein peptides facilitates database searching

Membrane proteins are fairly refractory to digestion especially by trypsin, and less specific proteases, such as elastase and pepsin, are much more effective. However, database searching using nontryptic peptides is much less effective because of the lack of charge localization at the N and C termini and the absence of sequence specificity. We describe a method for N-terminal-specific labeling of

A Practical Example Using VR in the Assessment of Brain Injury

Virtual Reality (VR) as a complementary tool for medical practitioners in the assessment and rehabilitation of people who have suffered a traumatic brain injury (TBI) is discussed. A pilot-study has been undertaken on a prototype VR assessment tool. The design involved nine occupational therapists with expertise in the care of traumatic brain injured patients and one (computer experienced) patient