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The intestinal lamina propria (LP) contains a diverse array of mononuclear phagocyte (MNP) subsets, including conventional dendritic cells (cDC), monocytes and tissue-resident macrophages (mÏ †) that collectively play an essential role in mucosal homeostasis, infection and inflammation. In the current review we discuss the function of intestinal cDC and monocyte-derived MNP, highlighting how these

Th2 cytokines like interleukin-4, -5, and -13 are regarded as important drivers of the immunopathology underlying allergic rhinitis (AR) and asthma. The present study explores the capacity of pentosan polysulfate sodium (PPS), a semi-synthetic heparin-like macromolecular carbohydrate, to bind Th2 cytokines and exert biological neutralization in vitro, as well as anti-inflammatory actions in vivo.

This chapters looks at the Swedish financial revolution in a long-term perspective. It begins with the establishment of the first formal financial organization, the Stockholm Banco in 1656, and follows the financial development until the end of the nineteenth century. The development of each part of the financial system is described in relation to the financial, economic, and political development

The adult adaptive immune system is comprised of a wide spectrum of lymphocyte subsets with distinct antigen receptor repertoire profiles, effector functions, turnover times and anatomical locations, acting in concert to provide optimal host protection and self-regulation. While some lymphocyte populations are replenished by bone marrow hematopoietic stem cells (HSCs) through adulthood, others eme

This text sheds light on the delicate practice of including different religious as well as nonreligious expressions in a shared room. The effects of design decisions in a “room of silence” at a Swedish hospital are studied over a transitional period of renovation of the space. We observe the impact of materiality in the room’s establishment, renovation, and usage, and show how the room’s interior

A probabilistic cellular automaton technique is employed in the simulation of dynamic discontinuous recrystallization (DDRX) in pure copper under hot deformation conditions. Important features of the present model are calibration of grain growth kinetics against the analytical solution and also the description of a misorientation-dependent grain boundary energy, valid in the entire range of misori

This paper presents algorithms for continuous-time quadratic optimization of impedance control. Explicit solutions to the Hamilton-Jacobi equation for optimal control of rigid-body motion are found by solving an algebraic matrix equation. System stability is investigated according to Lyapunov function theory, and it is shown that global asymptotic stability holds. The solution results in design pa

Abstract submitted to ISEE 2012 Theme: The Political Economy of Green Development By Rikard Warlenius PhD Candidate Human Ecology Division Lund University, Sweden 2011.11.24 Calculating Climate Debt. A Comparison and a Proposal The notion of climate debt has invoked widespread interest in the last few years. First conceptualized in 1999 within the Millennium movement for (financial) debt cancella