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Knowledge as a source of power in real estate organisations

Purpose: The purpose of the paper is to explore how knowledge contributes to value adding activities within real estate organisations. More specifically, the study aims to investigate; (1) how knowledge sharing activities are perceived in real estate organisations, (2) what motivates individuals to share knowledge and what incentives are used to support them, and (3) if employees in these organisa

Saudi Arabia

Comparable country profile that describes the evolution and practice of corporate Sustainability and Responsibility (CSR) in Saudi Arabia.

On the use of Titration Calorimetry to Study the Association of Surfactants in Aqueous Solutions

Isothermal titration calorimetry is increasingly becoming a common tool for the investigation of surfactant association processes. This can be associated with the development of new, sensitive and easy-to-operate commercial equipment, allied with the advantage of producing simultaneous information on the main thermodynamic parameters associated with the process under investigation. However, a sign

Uneven distribution of repetitive trinucleotide motifs in human immunoglobulin heavy variable genes

Insertions and deletions of entire codons have recently been discovered as a mechanism by which B cells, in addition to conventional base substitution, evolve the antibodies produced by their immunoglobulin genes. These events frequently seem to involve repetitive sequence motifs in the antibody-encoding genes, and it has been suggested that they occur through polymerase slippage. In order to bett

S100A9 as a pharmacological target molecule in inflammation and cancer.

Upon tissue injury and infection both stressed and dying cells can release proteins that normally reside inside the cells. Some of the released proteins become ligands of various cell surface receptors expressed by local cells and such proteins are denoted damage associated molecular patterns (DAMPs). Binding of some DAMPs to certain cell surface receptors induces signals emanating in the producti

The unique structure of Haemophilus influenzae protein E reveals multiple binding sites for host factors.

Haemophilus influenzae protein E (PE) is a multifunctional adhesin, involved in direct interactions with lung epithelial cells and host proteins, including plasminogen and the extracellular matrix proteins vitronectin and laminin. We recently crystallized PE and successfully collected X-ray diffraction data to 1.8 Å. Here we solved the structure of a recombinant version of PE and analyzed differen

Asymmetric waves in wave energy systems analysed by the stochastic Gauss-Lagrange wave model

The Gauss-Lagrange stochastic wave model is known to produce irregular waves with realistic degrees of asymmetry. We present the basic structure of the model and illustrate three of its characteristic properties: front-back asymmetry, particle orbits, and average horseshoe pattern. We also study the effect of a linear filter in a wave energy converting (WEC) system on asymmetry and on average powe

Approximate Optimal Periodogram Smoothing for Cepstrum Estimation using a Penalty Term

The cepstrum of a random process is useful in many applications. The cepstrum is usually estimated from the periodogram. To reduce the mean square error (MSE) of the estimator, the periodogram may be smoothed with a kernel function. We present an explicit expression for a kernel function which is approximatively MSE optimal for cepstrum estimation. A penalty term has to be added to the minimizatio

Maximizing leave-one-out likelihood for the location parameter of unbounded densities

We propose simple estimation of the location parameter for a density that is unbounded at the mode. The estimator maximizes a modified likelihood in which the singular term in the full likelihood is left out, whenever the parameter value approaches a neighborhood of the singularity location. The consistency and super-efficiency of this maximum leave-one-out likelihood estimator is shown through a

Prediction of Activation Energies for Aromatic Oxidation by Cytochrome P450

We have estimated the activation energy for aromatic oxidation by compound I in cytochrome P450 for a diverse set of 17 substrates using state-of-the-art density functional theory (B3LYP) with large basis sets. The activation energies vary from 60 to 87 kJ/mol. We then test if these results can be reproduced by computationally less demanding methods. The best methods (a B3LYP calculation of the ac

Artifacts in Absorption Measurements of Organometal Halide Perovskite Materials: What Are the Real Spectra?

Organometal halide (OMH) perovskites have attracted lots of attention over the last several years due to their very promising performance as the materials for solar cells and light-emitting devices. Photophysical processes in these hybrid organic inorganic semiconductors are still heavily debated. To know precise absorption spectra is absolutely necessary for quantitative understanding of the fund

Specific (CD2CD2SCHD2)-C-12-D-beta-C-12-D-gamma-C-13-H-epsilon Isotopomer Labeling of Methionine To Characterize Protein Dynamics by H-1 and C-13 NMR Relaxation Dispersion

Protein dynamics on the micro- to millisecond time scale is increasingly found to be critical for biological function, as demonstrated by numerous NMR relaxation dispersion studies. Methyl groups are excellent probes of protein interactions and dynamics because of their favorable NMR relaxation properties, which lead to sharp signals in the H-1 and C-13 NMR spectra. Out of the six different methyl