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One of the hallmarks of type 1 but also type 2 diabetes is pancreatic islet inflammation, associated with altered pancreatic islet function and structure, if unresolved. IL-1β is a proinflammatory cytokine which detrimentally affects β-cell function. In the course of diabetes, complement components, including the central complement protein C3, are deregulated. Previously, we reported high C3 expre

Anonymisation of assessments has been discussed for decades. It stems from a concern about unduly bias in assessment and grading. In Sweden, anonymised assessments were introduced in many universities a decade ago. It was rarely preceded by discussions on potential pedagogical consequences. Recent research on the effects of anonymisation does not confirm the hypothesis of reduced bias in grading.

Paediatric prospective studies of coeliac disease with longitudinal collection of biological samples and clinical data offer a unique perspective on disease risk. This Review highlights the information now available from international paediatric prospective studies on genetic and environmental risk factors for coeliac disease. In addition, recent omics studies have made it possible to study comple

This project investigates the empirical realities of shifting norms and practices around young children’s education in urban East Asia. In particular, it examines how parenting strategies are entangled with aspirations for human capital accumulation and upward social mobility, as well as the best interest of the child, and how these notions are reconciled and enacted differently along gender, gene

Before curation, there is collection. Before visitors engage with objects in an exhibition, collection managers engage with the objects and, in some cases, also the donors. It makes sense that especially when difficult pasts are involved, collection managers have affective encounters with the materiality before visitors do. So why has the affective turn focused mainly on engaging visitors’ emotion

This chapter examines a population of third language (L3) learners that has received little attention, namely heritage speaker (HS) L3 learners, who grow up speaking two languages in early childhood. Unlike traditionally studied L3 learners, who acquired their L2 as older children, HSs have two naturalistically acquired languages to draw from, which has been suggested to have implications for L3 a

In this interview, Prince Sisowath Thomico, a cousin of Cambodian King Sihamoni who has been politically active in a range of political movements and parties, discusses the role of the monarchy and what royalism might mean in Cambodia today, three decades after the Cambodian monarchy was reintroduced. He reflects on the historical trajectory of the Cambodian monarchy and royalism, and analyses how

BACKGROUND: Currently, there are no therapies targeting specific pathogenic pathways in myocarditis. IL (interleukin)-1 blockade has shown promise in preclinical studies and case reports. We hypothesized that blockade of IL1RAP (IL-1 receptor accessory protein), a shared subunit of the IL-1, IL-33, and IL-36 receptors, could be more efficient than IL-1 blockade alone. METHODS: We induced coxsackie

Organ-on-a-chip devices are predominately made of the polymer polymethylsiloxane (PDMS), exhibiting several attractive properties e.g., transparency, gas permeability, and biocompatibility. However, the attachment of cells to this polymer has proven challenging, especially for delicate primary cells e.g., small intestinal organoid-derived epithelial cells. Hence, a need to functionalize and coat t

The aim of the study is to research upper secondary teachers’ attitudes towards, and use of, critical perspectives in teaching literature in the subject of English in Sweden. This is done in relation to the inequality issues identified in the Swedish school context, the Swedish National Curriculum for the Upper Secondary School and the syllabi for English, along with a theoretical framework based

The following study compares Carlos Fuentes’ “Chac Mool” (1954) with Elena Poniatowska’s “Coatlicue” (2003). Both literary works are short stories that belong to a literary genre known as the Fantastic, which is, in turn, a genre in which a reader will be met with a credible setting, not too different from their own, but in which various supernatural elements manifest themselves and disturb the st

The Church of Sweden is marginalized in society and the membership of the Church is decreasing, which means that the church's economy is on the decline, but the demands on the Church by its members have not decreased. This is a comparative study that deals with the roles of deacons and priests and their contribution to the Church. The aim is to get an overview of similarities and differences i

The 1st of April 2018 an aviation tax was implemented in Sweden. With an event study approach this paper aims to provide an understanding of the outcome of the new policy. This by investigating if the tax causes significant effects on the stock returns of concerned flight carriers and whether the policy causes a significant change in the number of air passengers travelling from Sweden. By calculat

Since the CJEU’s creation, it has been significant to solidify and review European Law. However, rather than merely being the dispute arbiter of the European Union, it is also seen to be a driver for political change and integration. The involvement of the CJEU in political matters has often been associated with judicial activism. An area especially prone to this phenomenon has been fundamental ri

Tunisia is where all hope and rebellion started. After the self-immolation of Mohamed Bouazizi in 2010, the Jasmine Revolution spread to other Arab countries leading to the famous Arab Spring. Tunisia is depicted as the model of democratic transition in the Arab region and in the West. Transitional justice mechanisms have been implemented in the country, notably a Truth and Dignity Commission aimi