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Performance audit at the Swedish Supreme Audit Institution (SAI)

Supreme Audit Institutions (SAIs) constitute important democratic institutions, providing citizens with an independent analysis on how the Governmental Offices and the central public administration function. This paper reports on findings from a survey, submitted to all performance auditors at the Swedish SAI, on 3 May, 2011. The response rate was 70 per cent (65 out of 93 respondents). The survey

Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.

Anti-neutrophil cytoplasmic antibodies (ANCA) are thought to be pathogenic in ANCA associated vasculitis (AAV) by stimulating polymorphonuclear leukocytes (PMNs) to degranulate and produce reactive oxygen species (ROS). The aim of this study was to investigate if PMNs from AAV patients are more readily stimulated by ANCA compared with PMNs from healthy controls (HCs). Differences in ANCA character

Cryptochromes-a potential magnetoreceptor: what do we know and what do we want to know?

Cryptochromes have been suggested to be the primary magnetoreceptor molecules underlying light-dependent magnetic compass detection in migratory birds. Here we review and evaluate (i) what is known about these candidate magnetoreceptor molecules, (ii) what characteristics cryptochrome molecules must fulfil to possibly underlie light-dependent, radical pair based magnetoreception, (iii) what eviden

Exploring spontaneous-event marking though parallel corpora: Translating English ergative intransitive constructions into Norwegian and Swedish

English ergative verbs in one-participant constructions such as ‘The door opens’ often correspond to reflexive verbs or -S forms in Norwegian and Swedish. Following Kemmer (1993) such constructions profile spontaneous event meaning and belong to the middle domain. This study uses corpus methodology to explore spontaneous-event marking in Norwegian and Swedish from the point of view of Kemmer’s sug

Elevated Plasma Levels of Antimicrobial Polypeptides in Patients with Severe Sepsis.

We wanted to investigate if plasma levels of antimicrobial polypeptides (AMPs) are increased in severe sepsis and if they correlate with severity and mortality. Samples were collected from 31 sepsis patients at the intensive care unit. The Sequential Organ Failure Assessment (SOFA) score and 90-day mortality were registered, and inflammatory markers and AMP levels were measured by ELISA. A median

Vaccine for Atherosclerosis.

Atherosclerosis is an immune-mediated inflammatory disease of the arterial wall, with both the innate and adaptive immune systems responding to many endogenous and exogenous antigens. Both proatherogenic as well as atheroprotective roles have been identified for the immune system in atherosclerosis. Hence, it is conceivable that an immunomodulatory strategy via active immunization against many of

Sustaining innovation and improvement in the treatment of childhood cancer: lessons from high-income countries

Cancer in children and adolescents is rare and biologically very different from cancer in adults. It accounts for 1.4% of all cancers worldwide, although this proportion ranges from 0.5% in Europe to 4.8% in Africa, largely because of differences in age composition and life expectancy. In high-income countries, survival from childhood cancer has reached 80% through a continuous focus on the integr

Molecular methods for identification and characterization of novel papillomaviruses.

Papillomaviruses (PV) are a remarkably heterogeneous family of small DNA viruses that infect a wide variety of vertebrate species and are etiologically linked with the development of various neoplastic changes of the skin and mucosal epithelia. Based on nucleotide similarity, PVs are hierarchically classified into genera, species and types. Novel human PV (HPV) types are given a unique number only

Literature, ICT and Globalization – Using Glogster in Teaching Francophone Literature

I detta konferensbidrag beskriver jag ett exempel på hur IKT (Informations- och kommunikationsteknik) kan användas i litteraturundervisning på gymnasiet i Sverige på ett sätt som gör det möjligt för eleverna att bli mer aktiva producenter av kunskap i en flexibel inlärningsmiljö samtidigt som man främjar en globaliserad litteratursyn, särskilt vad gäller fransk litteratur, som går bortom nationensIn this paper I describe an example of how ICT (Information and communication technologies) can be used in teaching literature at upper secondary level in Sweden in a way that lets the pupils become more active producers of knowledge in a flexible learning environment and promotes a globalized view of literature, especially of French literature, which goes beyond the nation’s borders.

Professional judgements in collaboration

Although intimate partner violence is far from a new problem in society, it has lately gained increased attention both by governments and by the research community. In 2007, the Swedish government issued an action plan for “combating men’s violence against women, violence and oppression in the name of honour and violence in same-sex relationships” (2007/08:39), which included a call for increased

The state of water in non-ionic surfactant solutions and lyotropic phases : Oxygen-17 magnetic relaxation study

Water 17O longitudinal and transverse relaxation rates have been measured in aqueous solutions and mesophases of the non-ionic alkyl oligo(ethylene oxide) surfactants C12En (n = 4, 5, 8) over wide ranges of temperature and concentration. In addition, two reference systems have been investigated: high molecular weight poly(ethylene oxide) and the dimer 1,2-dimethoxy ethane. The relaxation data are

Bacterial attachment to uro-epithelial cells : mechanisms and consequences.

Microbial attachment to mucosal surfaces is a first step in mucosal infection. Specific interactions between microbial surface ligands and host receptors influence the distribution of microbes in their sites of infection. Adhesion has often been regarded as a sufficient end point, explaining tissue tropism and bacterial persistence at mucosal sites. Adherence, however, is also a virulence factor t

High-order harmonic generation in xenon : Intensity and propagation effects

We present experimental results on high-order harmonic generation in xenon, using a Nd:YAG laser (1064 nm). The harmonic generation efficiency is studied as a function of the laser intensity in the 1013 W/cm2 range. The harmonic conversion rates show a significant change of behavior when the medium becomes ionized (∼1013 W/cm2). This effect can be understood as the change of the nonlinear response