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Popular Abstract in Swedish Hur börjar en infektion och vad avgör vem som drabbas? Hur ser den sjukdomsframkallande bakterien ut, och hur försvarar vi oss mot dess angrepp? Vi studerar dessa frågor med urinvägsinfektioner som modell. De flesta urinvägsinfektioner orsakas av E. coli bakterier med speciella ytstrukturer som de använder för att angripa slemhinnan i urinvägarna. Genom sin starka förmUrinary tract infections (UTI) are among the most common infections in man. Despite their prevalence, information on the molecular mechanisms defects that explain the increased susceptibility to disease are lacking. This study focused on mucosal inflammation and the molecular mechanisms by which uropathogenic Escherichia coli activate this response. P fimbriae are expressed by most E. coli strain

In a joint research project – Human Factors in Air Navigation Services, HUFA – between the Swedish Civil Aviation Administration and Lund University the focus is on human and organizational factors and safety in air traffic control. The Swedish Air Navigation Services (ANS) are undergoing major organizational changes in order to adapt to changing demands on efficiency and technical development in

We derive [Cu/Fe] for 117 giant stars in 10 globular clusters (M3, M4, M5, M10, M13, M15, M71, NGC 7006, NCG 288, and NGC 362) and find that globular cluster Cu abundances appear to follow [Cu/Fe] trends found in the field. This result is interesting in light of recent work, which indicates that the globular cluster ω Centauri shows no trend in [Cu/Fe] with [Fe/H] over the abundance range -2.0<[Fe

To measure organizational climate for creativity and innovation Ekvall’s 10-dimension model is widely used both in research and in practice. The model consists of the 10 dimensions; challenge, freedom, idea support, trust, dynamism, playfulness, debate, conflicts risk-taking, and idea time. Outgoing from these dimensions Ekvall (1996) developed the Creative Climate Questionnaire (CCQ), shown to di

The paper looks at the development philosophy behind the establishment of the Lukzum Samdrupling, the first Tibetan refugee settlement in India and how it was received by the refugees. After reviewing Chinese development concepts in the 1950’s and 1960’s with an emphasis on Tibet, the paper explores the central concepts of Indian development philosophy at that time, such as cooperative, scientific

Popular Abstract in Swedish De allra flesta mikrobiella infektioner börjar på slemhinnan och en gemensam nämnare för patogena mikroberna är deras förmåga att stimulera ett immunsvar på just den plats som de infekterat. De patogena bakteriernas kommer först i kontakt med epitelcellerna, som bildar kroppens barriär mot omgivningen. Interaktionen mellan patogener och dessa celler leder till ett inflaMicrobial attachment to host cells plays a central role in the induction of inflammatory responses and the production of the disease. Uropathogenic Gram negative bacteria carry surface lectins that specifically recognize oligosaccharide receptor epitopes expressed on glycolipids or glycoproteins. The resulting attachment may facilitate the action of other virulence factors, but may also activate t

Popular Abstract in Swedish Bröstcancer är den mest frekventa cancerformen bland kvinnor, 1 av 8 drabbas någon gång under sin livstid av sjukdomen. Införandet av mammografi har gjort att cancern upptäcks tidigare och detta, tillsammans med effektivare behandlingsformer, har bidragit till att dödligheten i bröstcancer sjunkit de senaste decennierna. Antalet fall av bröstcancer ökar dock ständigt, fBreast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide. Breast tumours are extremely heterogeneous, and each patient’s disease has different causes, prognosis and appropriate treatments associated with it. To enable a more individualised therapy, there is a substantial need for better characterisation of tumours and a deeper understanding o

Ergonomics are, in most cases, focusing on the human being when evaluating assembly system designs. This results in the human performance being expressed isolated from the technical environment. On the other hand, technicians are prone to concentrate on the hardware. These conditions underline the need to pursue a more integrated evaluation and design procedure in order to avoid the drawbacks of t