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Although adenoviruses (AdVs) possess advantageous features as vectors, several challenges remain. These include a high prevalence of neutralizing antibodies against certain AdV types and the inability to efficiently transduce CAR-deficient cells and tissues. We showed previously that lactoferricin (Lfcin) enhances CAR-independent HAdV-C5 infection of epithelial and T-cells. Here, we assessed the a
Ischemic stroke causes transient increase of neural stem and progenitor cell (NSPC) proliferation in the subventricular zone (SVZ), and migration of newly formed neuroblasts toward the damaged area where they mature to striatal neurons. The molecular mechanisms regulating this plastic response, probably involved in structural reorganization and functional recovery, are poorly understood. The adapt
Abstract Itch accompanies most inflammatory skin diseases but may occur as a solitary sensation in otherwise normal skin. Chronic itch often requires combined treatments but some cases remain therapy resistant. Complementary medicine is becoming increasingly popular among patients. Acupuncture is the oldest and most well-studied alternative option with evidence-based effect on pain. This article s
The S.T.A.R. Design Studio (Space and Terrestrial Architectural Research) studies pre-industrial habitats in i.a. Tanzania, and develops design concepts for future habitats in space in cooperation with Johnson Space Centre, Houston, Texas. In both cases our studies focus on "extreme" circumstances. Perhaps studying the conditions of a crew sealed in a capsule can better prepare us for the problems
In this chapter two examples are presented were the Swedish legislator built market mecanisms into the unemployment insurance system and the pension system. The two market mecanisms were designed to make trade unions with high unemployment show restraint in collective wage bargaining and to make elderly people chose two postpone retirement. The aim of the legislation was to make the opposite choic
Innovation and industrial dynamics have grown in importance over the last 40-50 years as we have moved towards a more knowledge intensive society. In an effort to understand these developments in society new research fields have emerged such as innovation and entrepreneurship studies. In general, these two research fields are regarded as rather closely interlinked. In this study we elaborate on th
In this paper we examine the ambiguities between extrinsic and intrinsic parameters in the uncalibrated structure and motion problem. The Jacobian J of the reprojection error is considered, treating each camera separately. Ambiguities correspond to linear dependencies in the column space of J and we thus detect and quantify these by using the condition number of selected combinations of columns of
Abstract in UndeterminedThis paper presents a qualitative thematic analysis of reader comments posted in connection to a series of articles published after Encyclopaedia Britannica’s announcement to forego its print edition. It shows how ideas of what information is, are entangled with ideas of what a certain medium is and does. Two research questions guide the analysis: 1) How are encyclopedias a
