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Comparison of conventional and Si-photomultiplier-based PET systems for image quality and diagnostic performance

BACKGROUND: A new generation of positron emission tomography with computed tomography (PET-CT) was recently introduced using silicon (Si) photomultiplier (PM)-based technology. Our aim was to compare the image quality and diagnostic performance of a SiPM-based PET-CT (Discovery MI; GE Healthcare, Milwaukee, WI, USA) with a time-of-flight PET-CT scanner with a conventional PM detector (Gemini TF; P

Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia

Chronic autoimmune thrombocytopenic purpura (ATP) is a common hematologic disorder in which platelet-specific autoantibodies bind to platelets and enhance their destruction by the reticuloendothelial system. While there has been considerable investigation of the humoral immune abnormalities in ATP, little work has been performed on the cellular immunoregulatory aspects of this autoimmune disorder.

Interaction with the host : the role of fibronectin and extracellular matrix proteins in the adhesion of Gram-negative bacteria

The capacity of pathogenic microorganisms to adhere to host cells and avoid clearance by the host immune system is the initial and most decisive step leading to infections. Bacteria have developed different strategies to attach to diverse host surface structures. One important strategy is the adhesion to extracellular matrix (ECM) proteins (e.g., collagen, fibronectin, laminin) that are highly abu

Exploring the network of actors contributing to mitigating flood risk in Lomma, Sweden

Urban flood risk is a big and growing concern in Sweden. Although much focus is placed on rainfall, hydrology, and engineering conceptualizations of both consequences and solutions, social research contributes to explaining and understanding risk and how actors perceive, construct, and manage it together. This paper applies social network analysis to investigate the network of actors in Höje river

The Law of Nations

This chapter gives an account of Pufendorf’s discussion and use of the law of nations. It first outlines his distinctive contribution to contemporary discussions of the topic, namely his rejection rejection, against Grotius, of a specific “positive” law of nations distinct from the law of nature. Secondly it explains how this position relied on Pufendorf’s voluntarist conception of law as the comm

TWO THEOLOGIANS AND “WHY I AM NOT A CHRISTIAN”

Bertrand Russell’s speech “Why I Am Not a Christian” (1927) triggered many theologians to defend Christian beliefs. Aside from his rational criticism of the so-called “proofs” of God’s existence, it is his humorous irony as a rhetorical weapon that made many abandon their faith in Christianity and become atheists or at least agnostics. In this article I examine two British theologians’ unsuccessfu