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Leader-follower perspectives

This entry provides a presentation of different leader-follower perspectives. Traditional leadership research has a psychological orientation and focuses on leaders as persons. Leaders are conceptualized as active communicators and subordinates/followers as more or less passive recipients, which implies a monologic, transmission-oriented view of communication. In recent years, there has been a tur

The anti-angiogenic peptide anginex greatly enhances Galectin-1 binding affinity for glycoproteins

Angiogenesis is a key event in cancer progression and therefore a promising target in cancer treatment. Galectin-1, a β-galactoside binding lectin, is up-regulated in the endothelium of tumors of different origin and has been shown to be the target for anginex, a powerful anti-angiogenic peptide with anti-tumor activity. Here we show that when bound to anginex, galectin-1 binds various glycoprotei

Clinicopathological concordance in dementia diagnostics.

OBJECTIVE: Accurate distinction between dementia subtypes is important for patient care and pharmacological treatment. Continuing systematic comparisons of clinical and neuropathological dementia diagnoses may provide a basis for further improvement of the diagnostic procedure. The purpose of this study was to investigate concordance between clinical dementia diagnosis and neuropathological findin

Speech tempo

This article presents an overview of the literature on speech tempo and the topics dealt with. Tempo is not one of the more frequently explored areas of speech research, and any possible consequences of tempo variation for other phonetic phenomena have all too often been taken for granted. Unfortunately, this field is complicated by pitfalls of definition and hazards of numerical treatment. A gla

Insulin secretion is highly sensitive to desorption of plasma membrane cholesterol.

Cholesterol-rich clusters of SNARE (soluble NSF attachment protein receptor) proteins have been implicated as being important for exocytosis. Here we demonstrate the significance of cholesterol for normal biphasic insulin secretion in mouse beta cells by removal of cholesterol from the plasma membrane using methyl-beta-cyclodextrin (MBCD). Maximal inhibition of insulin secretion in static incubati

Critical perspectives on leadership

This chapter reviews the emerging body of literature on critical theories of leadership. It begins by putting critical approaches to leadership in the context of broader debates about leadership. It notes that most existing work builds on either functional or interpretive assumptions. After noting some of the shortcomings with these directions, this chapter offers an alternative set of ideas based