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T-cell recognition of lipid peroxidation products breaks tolerance to self proteins

Peroxidation of polyunsaturated fatty acids in lipoproteins and cell membrane phospholipids occurs in many situations in the body, both under normal and pathological conditions. Low-density lipoprotein is particularly prone to oxidation and is believed to be a pathogenetic component in atherogenesis. Both antibody responses and T-cell responses to oxidatively modified lipoproteins have been demons

Parallel gene expression profiling of mantle cell lymphoma - How do we transform 'omics data into clinical practice

DNA microarray technology has been a valuable tool to provide a global view of the changes in gene expression that characterize different types of B cell lymphomas, both in relation to clinical parameters but also in comparison with the non-malignant counterparts. The number of transcripts that can be analyzed on an array has dramatically increased, and now most commercially available arrays cover

Struggling to Make Ends Meet : Lone Mothers and Intergenerational Support in Sweden

Economic divisions have deepened in Sweden in recent years, and lone mothers are one group where the poverty rate has increased most (Salonen 2014). At the same time, di erences between the situations of lone mothers have also increased (Lundqvist 2014). As a consequence, intergenerational support from grandparents in terms of care and nancial transfers are important (see also Halleröd 2008). Thi

Sven Nilsson and the postglacial fauna of Scania

The Lund professor Sven Nilsson achieved international fame in the nineteenth century in such diverse subjects as geology, zoology, and archaeology. This man of contrasts is described as brilliant but temperamental and touchy, assertive, with a fondness for sensation but simultaneously highly sensitive to criticism. His research on faunal history was pioneering, and many of the results are still v

Inverted cultures in the pictorial ceremonial of the suicide bomber: The case of Reem Raiyshi

On the 24th of January in 2004 a portrait of Reem Raiyshi and her son was published in the Swedish newspaper Aftonbladet. In a short notice the reader was informed that on the 14th of January Reem Raiyshi had killed herself in a terrorist attack at a border crossing between Israel and Gaza. The picture, a still frame from a video, was bought by Aftonbladet from AFP, but has also circulated on the

Blastocystis ratti induces contact-independent apoptosis, F-actin rearrangement, and barrier function disruption in IEC-6 cells

Blastocystis is an enteric protozoan purportedly associated with numerous clinical cases of diarrhea, flatulence, vomiting, and other gastrointestinal symptoms. Despite new knowledge of Blastocystis cell biology, genetic diversity, and epidemiology, its pathogenic potential remains controversial. Numerous clinical and epidemiological studies either implicate or exonerate the parasite as a cause of

Eco-modernity nordic style : The challenge of aligning ecological and socio-economic sustainability

This chapter explores the Nordic countries’ attempts to reconcile their environmental front-runner ambitions with their high productivity as advanced welfare states. On the one hand, the Nordics have taken leading positions in promoting environmental issues on the international stage. On the other hand, however, their high productivity, which is needed to support their welfare aspirations, has mad

Structured Laser Illumination Planar Imaging: New horizons for the study of spray dynamics, thermometry and droplet sizing

Thefirst reported applications of laser sheet imaging for the study of atomizing sprays date from the mid 1980th.Since those early tries, blurring effects from the light being scattered multiple times by the surrounding dropletswere already observed and reported. While s trategies in suppressing part of this multiple light scatteringcontribution, were known for transmission imaging (e. spatial Fou

Spatial Planning and Sociology of Law: Sustainable development issues in constructing infrastructure for the third generation mobile telephone system in Sweden

The infrastructure for the third generation of mobile telephony, UMTS, is under construction in Sweden. Within three years four operators were to build competing systems to cover 99,98 % of the population. The case of the 3G infrastructure illustrates how sustainability issues are handled in planning and environmental management, with conflicting goals between institutional levels and contradict