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Speech tempo

This article presents an overview of the literature on speech tempo and the topics dealt with. Tempo is not one of the more frequently explored areas of speech research, and any possible consequences of tempo variation for other phonetic phenomena have all too often been taken for granted. Unfortunately, this field is complicated by pitfalls of definition and hazards of numerical treatment. A gla

SGX-Bundler: speeding up enclave transitions for IO-intensive applications

Process-based confidential computing enclaves such as Intel SGX can be used to protect the confidentiality and integrity of workloads, without the overhead of virtualisation. However, they introduce a notable performance overhead, especially when it comes to transitions in and out of the enclave context. Such overhead makes the use of enclaves impractical for running IO-intensive applications, suc

Increased ventilatory response to carbon dioxide after dive training

Introduction: Divers are reported to have a lower ventilatory response to elevated levels of carbon dioxide (CO₂) than non-divers. Hypoventilation with CO₂ retention during diving is potentially dangerous. It is unknown if CO₂ retention is largely inherited or develops during diving training. We aimed to investigate if a military dive training course would influence the ventilatory response to CO₂

Hydration gradients drive lipid self-segregation

Evaporation from a multicomponent aqueous mixture not only establishes a hydration gradient but may also lead to composition gradients in the other components. Here, we show that such a gradient induces a strong segregation between two phospholipids that differ only in the saturation of their acyl chains. Using high-resolution confocal Raman microscopy combined with small- and wide-angle X-ray sca

Cytokines and Neutrophils in the Urinary Tract Mucosa

This study investigated the urinary tract cytokine reponse to infection and the role of chemokines for neutrophil recruitment to the urinary tract. The results suggest that 1) IL-8 and TGFb are consitutively produced by uroepithelial cells in vivo, and that uroepithelial cells are stimulated to produce IL-1b and IL-6 by uropathogenic Escherichia coli. 2) MIP-2 (mouse IL-8 homologue) plays an impor

Certain humans, certain animals : attitudes in the long term

Do certain humans and animals have greater value than other humans and animals? The question will be discussed using some examples from pre-Christian burial practices and other depositions of human and animal bones in Scandinavia. During the pre-Christian period it seems that certain humans and certain animals were buried in graves made for the purpose, while other humans and animals were deposite

Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists

A collection of iminocoumarylmethyl glycoside derivatives have been prepared by copper-catalyzed multi-component reaction of carbohydrate propargyl derivatives, sulfonyl azides, and salicylaldehyde or o-hydroxy acetophenone. The method is simple, versatile to all three components, and exceptionally high yielding. The carbohydrate N-sulfonyl iminocoumarine hybrid molecules were evaluated for bindin

Association between the use of fondaparinux vs low-molecular-weight heparin and clinical outcomes in patients with non-ST-segment elevation myocardial infarction.

Fondaparinux was associated with reduced major bleeding events and improved survival compared with low-molecular-weight heparin (LMWH) in a large randomized clinical trial involving patients with non-ST-segment elevation myocardial infarction (NSTEMI). Large-scale experience of the use of fondaparinux vs LMWH in a nontrial setting is lacking.

Mining as an underground space producing activity: A financial point of view

Urbanization has resulted in a gigantism of urban complexes and in many environmental and social problems. The situation on the surface and the principles of sustainable development compel urban planners to utilize the urban underground space, which for centuries has been almost exclusively the application field of mining. More often than not spatial planning in urban areas allocates various land-