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Severity of mild cognitive impairment in early Parkinson's disease contributes to poorer quality of life

BACKGROUND: Poor quality of life (QoL) is a feature of people with Parkinson's disease (PD) who develop dementia. The relationship between mild cognitive impairment in PD (PD-MCI) and QoL is less clear. To address this, we studied the impact of varying severities of cognitive impairment on QoL in a cohort of non-demented patients with early PD.METHOD: Patients with newly diagnosed PD (n = 219) and

Do socio-technical systems cognise?

The view that an agent’s cognitive processes sometimes include proper parts found outside the skin and skull of the agent is gaining increasing acceptance in philosophy of mind. One main empirical touchstone for this so-called active externalism is Edwin Hutchins’ theory of distributed cognition (DCog). However, the connection between DCog and active externalism is far from clear. While active ext

Identity, Social Media and Politics: How Young Emirati Women Make Sense of Female Politicians in the UAE

Social media offered new opportunities for politicians to engage withpublic. However, little research explored public perceptions of womenpoliticians, and their role in women empowerment, especially in nonWesterncontexts. This study used the qualitative methodology toexplore how young Emirati women made sense of women politicians andtheir social media posts. Drawing from the intersectionality theo

Analysis of the vascular sounds of the arteriovenous fistula's anastomosis

In this paper, the vascular sounds of the arteriovenous fistula at the anastomosis and five centimeters downstream the anastomosis were analyzed. The analysis of the sounds was based on features extracted from the power spectral density (PSD) and wavelet decomposition. The database consists of 15 recordings at the anastomosis and 15 reference recordings obtained from 15 patients. The results showe

Evaluation of the Sialidase Inhibitor Oseltamivir in GNE-associated Thrombocytopenia

Background: GNE encodes UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase, the rate limiting enzyme of sialic acid biosynthesis. Biallelic variants in GNE have recently been associated with severe isolated macrothrombocytopenia, attributed to an increased clearance of desialylated platelets. Interestingly, treatment with the sialidase inhibitor oseltamivir has been reported to increa

Are My Employees Able to and Do They Want to Work? : The Baseline Investigation in a Follow up Study Regarding Managers’ Attitudes and Measures to Increase Employees’ Employability in an Extended Working Life

Background: The demographic change affects the retirement age, which has been postponed in many countries. Therefore, the number of senior employees is increasing in the world. However, managers’ attitudes towards their employees’ employability affect the employees’ possibilities regarding whether they can and want to work. Objective: The aim of this study was to evaluate managers’ attitudes towar

Management, Measures and Maintenance: : Success and Setbacks in Interventions Promoting a Healthy and Sustainable Employability and Working Life for All Ages

Background: The labour force is ageing due to the demographic change and the postponement of old-age retirement in many countries. Objective: In order to increase the possibility for employees to maintain their employability and to keep working in an extended working life this intervention project tested a distance education as a technique to integrate a theoretical model for a sustainable working

Empowered or Protected? : The ‘problem’ of complainants’ rights in Danish and Norwegian preparatory works on criminal procedure

In the mid-2000s, Danish and Norwegian criminal procedural law underwent legislative amendments to strengthen the rights of complainants in cases of sexual violence and other cases of serious violations. While in Norway complainants were afforded participatory rights and stronger legal representation in court, this was largely not the case in Denmark. The aim of this chapter is to identify how the