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Gaia Data Release 3: Chemical cartography of the Milky Way

Context. The motion of stars has been used to reveal details of the complex history of the Milky Way, in constant interaction with its environment. Nevertheless, to reconstruct the Galactic history puzzle in its entirety, the chemo-physical characterisation of stars is essential. Previous Gaia data releases were supported by a smaller, heterogeneous, and spatially biased mixture of chemical data f

Expression of Toll-like receptor 9 in nose, peripheral blood and bone marrow during symptomatic allergic rhinitis.

BACKGROUND: Allergic rhinitis is an inflammatory disease of the upper airway mucosa that also affects leukocytes in bone marrow and peripheral blood. Toll-like receptor 9 (TLR9) is a receptor for unmethylated CpG dinucleotides found in bacterial and viral DNA. The present study was designed to examine the expression of TLR9 in the nasal mucosa and in leukocytes derived from different cellular comp

Adaptation of Work Places and Homes for the Disabled Using Computer-aided Design

When adapting environments for the physically disabled, it is important to encourage and activate not only the person concerned, but also other people involved or affected. A computer aided planning tool has been developed to support the participation of all persons involved, as well as supporting the planner’s (e.g. an occupational therapist) design of the environment. The prototype development a

Usability and perception of an architectural VR-model of an office building

It is important that the costs and effort in making a Virtual Reality (VR) model support its purpose in the specific context in which it is used. The present research aims to clarify which properties in VR-models contribute to improved experience of aspects of the model that are relevant in the use context and which therefore improve the models’ usability in the social processes of which they are

Introducing “medarbetarskap” as a concept facilitating work related relationships: Theoretical considerations in an airport change process.

The Swedish Air Navigation Service Provider, Luftfartsverket, together with Stockholm-Arlanda airport are implementing a new socio-technical concept called collaborative decision making. New technology and work procedures in collaborative decision making are directly affecting all organizations in an airplane turn-round process, and indirectly affecting legislators, authorities, suppliers, and pas

Health workers’ perspectives on the quality of maternal and newborn health care around the time of childbirth : Results of the Improving MAternal Newborn carE in the EURO Region (IMAgiNE EURO) project in 12 countries of the World Health Organization European Region

BACKGROUND: Health workers' (HWs') perspectives on the quality of maternal and newborn care (QMNC) are not routinely collected. In this cross-sectional study, we aimed to document HWs' perspectives on QMNC around childbirth in 12 World Health Organization (WHO) European countries.METHODS: HWs involved in maternal/neonatal care for at least one year between March 2020 and March 2023 answered an onl

Studies on signaling pathways induced by FLT3, an important oncogene in AML

Popular Abstract in Swedish Vår kropp består av olika celler som kommunicerar med varandra genom signalering. Cellerna tar emot signaler från omgivningen med hjälp av proteiner som sätter sig fast på deras yta genom mottagare, så kallade receptorer. När receptorerna får signaler skickas de vidare in i cellkärnan där det bestäms hur cellen ska agera. Tyrosinkinasreceptorer är proteiner som sitter pFLT3, a receptor tyrosine kinase, is expressed in hematopoietic progenitor cells. FLT3-ITD (internal tandem duplication) and D835 mutations are found in approximately 30% and 7% of Acute Myeloid Leukemia (AML) patients respectively, and correlate with a poor prognosis, thus making the mutated receptor a potential therapeutic target. FLT3 mutations cause constitutive activation of intrinsic tyrosin

Team climate and safety culture in air traffic control

In a joint project – Human Factors in ANS, HUFA - between the Swedish Civil Aviation Administration and Lund University the aim is to find out how a new team-based organization and the introduction of a new air traffic control system will affect safety culture and psychosocial working environment by changes in organizational climate, team climate and leadership. All in all, four studies will be co

Application of the Essential Facilities Doctrine to data: The doctrine's applicability to data in relation to fundamental rights

Förevarande uppsats analyserar utvecklingen av doktrinen om ’essential facilities’ i EU rättspraxis under Artikel 102 TFEU och vidare, i vilken utsträckning kan leveransvägran, särskilt doktrinen om ’essential facilities’ vara applicerbar på data och hur relaterar de fundamentala rättigheterna (näringsfrihet och rätt till egendom) till sådan tillämpning. Analysen av utvecklingen i rättspraxis, säThe thesis examines the development of essential facilities doctrine in EU case law under Article 102 TFEU and further, to what extent can refusal to supply, in particular the essential facilities doctrine, be applicable to data and how do fundamental rights (the freedom to conduct business and the right to property) relate to such extension. The analysis of the development of the case law, espe

Pyridoxine reduces cholesterol and low-density lipoprotein and increases antithrombin III activity in 80-year-old men with low plasma pyridoxal 5-phosphate

We have previously observed that pyridoxine treatment reduced plasma total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol concentrations and increased antithrombin III (AT III) activity in atherosclerotic patients with subnormal plasma pyridoxal 5-phosphate (PLP) levels. In order to confirm these results, we selected 17 males with low plasma PLP levels from a group of 122 80-year-o

Patient Outcomes after Heart Transplantation in Sweden between 1988 and 2017 : Continuous Improvement in Survival

PURPOSE: To investigate the survival of heart transplant (HTx) recipients during different time periods in Sweden. We hypothesized that the survival for HTx recipients has improved following advancements in the management of these patients. METHODS: Data was obtained through the database of the organ exchange organization Scandiatransplant. All patients who underwent HTx in Sweden between Jan 1988

Worldwide First Successful and Reproducable Long-Term Survival up to Half a Year : Completed Preclinical Study with Life-Supporting Orthotopic Pig-to-Baboon Cardiac Xenotransplantation (oXHTx) Fullfilling the ISHLT Prerequisite for Clinical Cardiac Xenotransplantation

PURPOSE: Major hurdles in oXHTx are the delayed xenograft rejection, the early perioperative cardiac xenograft dysfunction (PCXD) and the pig heart overgrowth, which were solved in this study with a costimulation blockade, a new non-ischemic cold preservation and a growth inhibition by anti-proliferative drugs. Aim was to achieve a 90-days-survival of minimal 60% (6 of 10 baboons) in this life-sup

Cross-borehole electrical monitoring in groundwater remediation projects : understanding the flow path of remediation agents

In-situ remediation of contaminated groundwater often relies on the installation of a treatment zone degrading the pollution plume. In such projects, adequate delivery of remediation agents in the whole target volume is not trivial. Monitoring the spatial distribution of injected reagents is important for engineers and decision-makers, in order to determine the need of more careful injection in so

Samfinansiering av indirekta kostnader för forskningsbidrag från National Institutes of Health I 201

Brevmall Postadress Box 117, 221 00 Lund Besöksadress Kemicentrum, Sölvegatan 39B, Telefon 046-222 9399, 046-222 00 00, E-post Kjell.Josefsson@fs.lu.se Rektor Samfinansiering av indirekta kostnader för forskningsbidrag från National Institutes of Health Bakgrund Universitetet deltar i flera forskningsprojekt finansierade med amerikanska statliga medel, varav den största andelen kommer från Nationa

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/samfinansiering-av-indirekta-kostnader-for-forskningsbidrag-fran-national-institutes-of-health.pdf - 2026-06-03

Implementing Dynamic Travel Time Calculation in EMS Simulations : Impacts on Prehospital Stroke Care and Transportation

Preparing travel time data can be a time-consuming process, which greatly limits the flexibility of transport simulation models. In the current paper, we present an approach to integrate a routing engine locally in an existing modeling framework, hence enabling to dynamically calculate travel times in the constructed emergency medical services (EMS) simulation models. This integration eliminates t