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The HELLP (Hemolysis, Elevated Liver enzyme, and Low Platelet) syndrome requires close monitoring of rapid changes in hemostasis. A bedside viscoelastic test--Sonoclot--was used together with coagulation, liver and hemolysis laboratory analyses in three parturients with the HELLP syndrome up to 10 days postpartum. Principal component analysis (PCA) was used to reduce the dimensionality of this mul
Adsorption of 0.2 ML Na on Al(1 0 0) at room temperature yields a disordered Al(1 0 0)-(1 x 1)-Na phase, which transforms reversibly to a well-ordered Al(1 0 0)-(root5 x root5)R27degrees-Na phase on cooling below 250 K. Based on low energy electron diffraction (LEED) and high resolution core-level spectroscopy (HRCLS) measurements, and on ab initio calculations, it is concluded that the structure
Calcitonin gene-related peptide (CGRP) and related peptides may be involved in migraine pathogenesis. To understand their vasomotor role in the cerebral circulation, we performed two studies, a pressurized arteriography study of the middle cerebral artery (MCA) and a genuine closed cranial window (gCCW) in vivo study. Using the pressurized arteriography model rat MCAs were mounted on micropipettes
Differential gene expression analysis, using high-density microarray chips, demonstrated 300-400 genes to be deregulated in mantle cell lymphomas (MCLs) compared with normal B-cell populations. To investigate the significance of this genetic signature in lymphoma etiology and diagnostics, we selected 90 annotated genes involved in a number of cellular functions for further analysis. Our findings d
Popular Abstract in Swedish Med ett historiskt perspektiv analyserar denna avhandling erfarenheter och identitetsskapande processer hos en grupp kvinnliga arbetare, cashewarbeterskor, i den sydindiska delstaten Kerala-välkänd för dess radikala befolkning och höga sociala indikatorer för invånarna. Cashewarbeterskorna utmanar den stereotypa bilden av kvinnor i ?Tredje Världen?, genom att de sedan 1Since the 1930s female cashew workers have constituted a majority of the registered workers in the South Indian State of Kerala and today number some 200,000. This group challenged the stereotypical view of Third World women because they were organized into unions, worked in the formal sector, and were literate. The background for this thesis has been the ?Kerala Model?, i.e., the political contex
Context:There is little information on the potential impact of serum 1,25-dihydroxyvitamin D [1,25(OH)(2)D] on bone health including turnover.Objective:The objective of the study was to determine the influence of 1,25(OH)(2)D and 25-hydroxyvitamin D [25(OH)D] on bone health in middle-aged and older European men.Design, Setting, and Participants:Men aged 40-79 years were recruited from population r
Calcitonin gene related peptide (CGRP) has a key role in migraine and recently CGRP receptor antagonists have demonstrated clinical efficacy in the treatment of migraine. However, it remains unclear where the CGRP receptors are located within the CGRP signaling pathway in the human trigeminal system and hence the potential antagonist sites of action remain unknown. Therefore we designed a study to
This paper presents a study of supported lipid bilayer (SIB) formation and subsequent protein binding using a sensor that combines localized surface plasmon resonance (LSPR) and quartz crystal microbalance with dissipation (QCM-D) monitoring. The LSPR activity arises from silicon oxide (SiOx) coated nanometric apertures in a thin gold film, which also serves as the active electrode of a QCM-D crys
In a recent population-based study, an elevated risk of the Metabolic syndrome (MetS) and type 2 diabetes was found in childless men compared to those who have fathered one or more children. Therefore, by using a larger cohort of more than 22 000 men from the Malmo Preventive Project (MPP) we aimed to expand our observations in order to evaluate the metabolic profile of childless men and to evalua
Hyperimmune mouse antisera against syngeneic adenovirus type 12 induced tumors and their 7 S and 19 S fractions of immunoglobulins obtained after combined diethylaminoethyl cellulose and Sephadex G-200 separation were tested against a rat adenovirus type 12 induced tumor by 51 Cr release technique. The same sera and their fractions were investigated with the colony inhibition technique for ability
How are people’s lives shaped by what they experience during infancy, childhood, and adolescence? How are their adult lives impacted by a sudden improvement or worsening in their early-life conditions?This dissertation aims at providing some insights about how specific changes in early-life conditions can affect individuals’ lives in the long-term. It focuses on three very different shocks to earl
We studied ice-nucleating abilities of particulate emissions from a modern heavy-duty diesel engine using three different types of fuel. The polydisperse particle emissions were sampled during engine operation and introduced to a continuous-flow diffusion chamber (CFDC) instrument at a constant relative humidity RHwater=110 %, while the temperature was ramped between −43 and −32 ∘C (T scan). The t
Climate denial takes many forms, ranging from outright denial of facts (literal denial), over distortion of facts (interpretive denial, e.g., denial of personal and global outcome severity), to the acknowledgement of facts but denial of their implications (implicatory denial, e.g., avoidance, denial of guilt, rationalization of own involvement). This study aimed at furthering the understanding of
This research set out to identify pathways from vulnerability and stressors to depression in a global population of young athletes. Retrospective data were collected at age 18–19 years from Athletics athletes (n = 1322) originating from Africa, Asia, Europe, Oceania, and the Americas. We hypothesised that sports-related and non-sports-related stressors in interaction with structural vulnerability
Hydrothermal processes are an attractive clean technology and cost-effective engineering platform for biorefineries based in the conversion of biomass to biofuels and high-value bioproducts under the basis of sustainability and circular bioeconomy. The deep and detailed knowledge of the structural changes by the severity of biomasses hydrothermal fractionation is scientifically and technological n
Objective: Detailed analysis of hematological manifestations (HM) in systemic lupus erythematosus (SLE) are limited and their clinical impact on disease remain obscure. Here, we aimed to decipher factors associated with different hematological abnormalities in SLE patients and to assess their impact on disease related outcomes. Methods: A dataset (GIPT) originating from SLE patients of six Europea
